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Deprivitis
Deprivitis is included in the category of antidepressant medications.
Pharmacodynamics
Deprivit is an antidepressant medicine of plant origin. Inside the extract of St. John's wort (a component of the drug) contains substances such as pseudo-hypericin with hypericin, as well as hyperforin. They have a harmonizing effect on the VNS and CNS.
The medicine helps to improve the state with apathy or mood decline, against which there is insomnia, a feeling of malaise and loss of appetite. The drug improves mood, and in addition, positively affects both the physical condition and mental abilities. Together with this, Deprivit positively influences working capacity.
Contraindications
The main contraindications:
- the presence of hypersensitivity to the components of drugs;
- a history of photosensitivity, (also associated with the intake of St. John's Wort medicine);
- Use in combination with MAOI (or in the period of 2 weeks before the start of therapy with DecIvit);
- Depression in severe form, against which there are thoughts of suicide;
- children's age less than 12 years (because there is no information on the effectiveness of drug use and its safety in patients at this age).
Side effects of the deprivitis
Taking medication can provoke the appearance of short-term side effects (but this happens rarely):
- manifestations of the organs of the National Assembly: occasionally there are headaches or dizziness;
- disorders of the function of the digestive tract: occasionally there are disorders in the digestive tract, as well as dryness of the oral mucosa;
- subcutaneous layer reactions and dermatological pathologies: single (in people with intolerance to sun rays), because of exposure to sunlight, burns may appear;
- systemic disorders: occasionally the blood pressure index increases and fatigue is observed;
- Immune disorders: occasionally allergy is noted, including itching and reddening of the skin;
- mental illness: occasionally there is a feeling of anxiety or anxiety. Single (in people with bipolar depression) increases the likelihood of a manic state.
Dosing and administration
Tablets are taken orally with food, washed down with water. The medicine can not be chewed.
Dosage regimen is 1-nu tablet three times a day. A positive drug effect is usually observed after 10-14 days of therapy. To achieve a full result of treatment, you should take Deprivit continuously for several weeks or even months. If the signs of the pathology persist after 4-6 weeks of drug use, it is necessary to cancel the treatment and consult a doctor.
Interactions with other drugs
The combination of St. John's wort medicines with MAOI or the use of the latter directly after the use of Deprivitis can lead to the potentiation of side effects of drugs.
Simultaneous use with other antidepressants (among them citalopram with sertraline, fluoxetine with fluvoxamine, and paroxetine) and derivatives of tryptane (among them naratriptan with sumatriptan and zolmitriptan), can also potentiate side effects (eg, vomiting, a feeling of fear or excitement, and besides this nausea).
In addition to the methods described above, the drug is able to interact with other drugs that are metabolized by enzymes of the hemoprotein system P450. The effect on enzymes can be observed after the use of drugs containing St. John's wort extract. Because of this, Deprivit can interact with other medicines in the period of 2 weeks after its cancellation.
The medicines of St. John's wort can potentiate the activity of many enzymes that are participants in the metabolism of other drugs. As a result of such reactions, a decrease in plasma values and the weakening of the medicinal properties of individual preparations are possible.
The drug weakens the properties of anticoagulants of an indirect type of action (this includes fenprocumone with warfarin), and in addition digoxin with nortriptyline, cyclosporine and theophylline with amitriptyline and indinavir. Therefore, they can be used in combination only with the permission of the doctor (in this case, it is necessary to monitor the indices of PTV and blood at the initial and final stage of therapy).
Simultaneous reception of Deprivitis with oral contraceptives of hormonal type can cause a weakening of their effectiveness, as well as the occurrence of bleeding in periods between menstruations.
Medical expert editor
Portnov Alexey Alexandrovich
Education: Kiev National Medical University. A.A. Bogomolets, Specialty - "General Medicine"
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Attention!
To simplify the perception of information, this instruction for use of the drug "Deprivitis" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.