The medication is administered in / with either the / m method, and in addition, either intrabusally or periarticularly, into the soft tissue or foci of the disease and into the rectum.
Use to obtain systemic effects.
The size of the / m dose depends on the severity of the pathology. To obtain a lasting effect, the size of the weekly dosage is calculated by multiplying the daily oral dosage by 7, and then administered by a single injection.
Dosages are determined individually, depending on the person's reaction to the drug and on the severity of the disease. The total duration of the course should be as short as possible. The patient needs medical care.
For children (also newborns), the recommended dosage should be lowered, but it should be changed first, taking into account the severity of the disease. Following the instructions of proportions relative to the weight and age of the child is secondary.
For people with adrenogenital syndrome, a one-time injection of 40 mg of medication is usually given, which is administered at intervals of 2 weeks.
With maintenance treatment, people with rheumatoid arthritis type receive a drug dose of 40-120 mg once a week.
The standard dosage for people with dermatological lesions is reduced in the case of a systemic course using SCS and is 40-120 mg - is administered intravenously once, at intervals of 1 month between the procedures. With severe dermatitis in acute form (due to ivy intoxication), the patient can be relieved by a single intravenous injection at a rate of 80-120 mg (the effect occurs after 8-12 hours). In the case of the development of a contact form of dermatitis (chronic type), it may be necessary to perform repeated procedures - injections are performed at intervals of 5-10 days. With the seborrheic form of dermatitis, the disease can be controlled with weekly injections of 80 mg.
After injection of the medicine in the amount of 80-120 mg to a person with bronchial asthma, the improvement of the condition is observed after 6-48 hours, and this effect lasts for several days and can go up to 2 weeks.
In people with an allergic rhinitis, intramuscular injection of 80-120 mg of LS can reduce the manifestations of the disease (6 hours after injection). The effect is kept for several days (maximum 3 weeks).
Use in situ for local effects.
In the case of osteoarthritis and rheumatoid arthritis, the dosage size for intravenous injection depends on the degree of severity of the pathology in a person, and also on the size of its joint. In chronic diseases, the administration procedure is allowed to repeat at intervals of 1-5 (and more) weeks, taking into account the degree of improvement that was observed with the 1st injection. The following are the general sizes of standard doses for different sites of administration:
- large joint (in the shoulder, knee or ankle) - the dose limits are 20-80 mg;
- middle joint (radiocarpal or in the region of the elbows) - dosage limits within 10-40 mg mg;
- small joint (in the interphalangeal or metacarpophalangeal region, as well as in the acromioclavicular or sternoclavicular area) -dose sizes are 4-10 mg.
With bursitis. Before injection, the injection site must be completely cleaned, and infiltration should be performed with novocaine (1% solution). Next, take the needle (size 20-24), attach it to a dry syringe, and inject it into the area of the joint bag to perform aspiration of the liquid. After the end of the procedure, the needle is left in place, and the syringe is replaced with the other, the one containing the required dose of drugs. When the injection is completed, you need to get the needle and apply a small bandage to the procedure.
Other diseases: ganglion and epicondylitis with tendinitis. Taking into account the severity of the pathology, the dosage range can be 4-30 mg. In the case of relapse or chronic disease, repeated injection may be necessary.
Injections that have a local effect in dermatological pathologies. First, the area of administration is cleared (use a suitable antiseptic - for example, 70% alcohol), and then a drug injection of 20-60 mg is given. If the affected area is too large, you need to divide the dosage of 20-40 mg into separate parts, and then insert them into different places on the damaged skin. Use the medicine carefully, so as not to introduce it in an amount that can provoke depigmentation - therefore, as a result of this, powerful necrosis can develop. Often, 1-4 injections are performed. Intervals between procedures depend on the duration of improvement observed after the initial injection.
Injection into rectal area.
It was found that addition to the main treatment of Depo-Medrol at dosages equal to 40-120 mg (with the help of microclysters) or by regular instillation of the substance 3-7 times in 7 days in a period of 2+ weeks showed a good result in people with ulcerative colitis. To control the state of health of the majority of patients it is possible with the help of injections of medicines in the amount of 40 mg with water (30-300 ml).
The use of GCS in children, as well as infants and adolescents, can provoke delays in growth processes that can become irreversible. Therefore, it is required to conduct therapy with a short-term course, with the restriction of the dose size to minimally effective parameters.
Newborns, as well as children who are treated with SCS for a long period of time, are at very great risk of increasing ICP rates. The use of drugs in high doses can provoke a child's appearance of pancreatitis.