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Denthol
Last reviewed: 23.04.2024
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Denthol is a gum treatment gel. Included in the group of local anesthetics.
Indications Denthol
Gel 7.5% is shown:
- for the immediate removal of pain in infants aged 4 months (during the appearance of milk teeth);
- as a quick effect of a temporary remedy for relieving young children from dental pain;
- as an anesthetic during dental procedures, and in addition, with minor damage to the oral mucosa;
- in the complex treatment of aphthous form of stomatitis.
Gel 10% are prescribed:
- for the prompt elimination of dental pain in children older than 6 years, as well as adults;
- in the form of a temporary analgesic for small lesions of the oral mucosa, as well as for pain in the gums;
- in the form of an anesthetic with short dental interventions.
Release form
Produced in gel form (7.5, and also 10%) in tubes of 15 g.
Dentol is 7.5%. In 1 g of the drug contains 75 mg of the active ingredient - benzocaine. Among the auxiliary elements: glycerin, PEG-75, PEG-8, E954 (sodium saccharinate), vitamin C, water, as well as red dye with cherry flavor.
Denthol 10%. In 1 g of the drug contains 100 mg of active substance - benzocaine. The excipients are the same as in Dentol 7.5%, but without the dye.
[1]
Pharmacodynamics
Benzocaine, which is an active component of the drug, is a local anesthetic. It prevents the passage of nerve impulses, and at the same time strengthens the stability of cell membranes under the influence of sodium ions - this allows complete anesthesia of mucous membranes and skin.
Pharmacokinetics
The effect of the gel begins already after 1 minute after its application. Duration of drug exposure is 20 minutes. Absorbed gel is quickly cleaved by hydrolysis (with the participation of blood plasma cholinesterases, and, less significantly, liver cholinesterases) to the state of decay products containing vitamin H1. Excretion of the drug is carried out by the kidneys, usually in the form of decay products.
Dosing and administration
Before starting the procedure, you need to wash your hands. After this, it is required to unscrew the lid of the tube and cut off the soldering on the hole. Gel on the gums is applied in a small amount - you need to process the area where the teeth are cut.
When used for the elimination of toothache, the medicine treats the area around the problem tooth.
The procedure is allowed to be performed 3-4 times a day. It is not recommended to use the medicine for more than a week.
[8]
Use Denthol during pregnancy
Pregnant women are prescribed only on the basis of the probability that the benefit to the mother will exceed the risk of developing negative effects in the fetus.
Side effects Denthol
Medicines containing benzocaine (2-10%) are generally well tolerated. They have no irritating effect, and are also non-toxic.
In general, the adverse reaction is due to the patient's hypersensitivity to the drug, or exceeding the permissible dose of drugs. If the patient has swelling, itching or hyperemia in the gel treatment area, it is necessary to cancel the use of the drug.
[7]
Overdose
The use of drugs in the required quantities eliminates the possibility of overdose. But if there are multiple mucosal lesions in the mouth, and the dose of the drug has been greatly exceeded, its absorption may increase, so that the concentration of the active substance in the blood serum will increase. As a result, edema may appear on the site of treatment, itching or hyperemia may begin. There is a single suppression or stimulation of the central nervous system, the suppression of the cardiovascular system, and in addition the development of methemoglobinemia.
If the patient has such symptoms, you should rinse your mouth with a solution of soda (warm), and then consult a doctor.
Interactions with other drugs
Dentol is not allowed to combine with sulfonamides, as well as with inhibitors of ChE. The latter can inhibit the metabolism of benzocaine, thereby increasing the likelihood of systemic intoxication. At the same time, benzocaine itself has the ability to inhibit the antibacterial activity of sulfanilamide drugs.
Storage conditions
It is necessary to keep medicines under standard conditions, but also beyond the reach of small children. The temperature should be in the range of 15-30 ° C.
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Shelf life
Dentol is allowed to be used for 4 years after the release of the gel.
Attention!
To simplify the perception of information, this instruction for use of the drug "Denthol" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.