Chlorhexidine

Chlorhexidine is a disinfectant antimicrobial drug used to treat gynecological diseases.

[1], [2]

Indications of the chlorhexidine

It is used to prevent the development of venereal pathologies (such as gonorrhea with syphilis, as well as chlamydia with trichomoniasis and ureaplasmosis) and complications of an infectious-inflammatory nature in gynecological and obstetrical practice: before gynecological operations, and also before abortion or childbirth; also before the installation of the spiral in the uterus and after it, and also before the intrauterine examination and before the diathermocoagulation of the uterine neck and after the procedure.

Treatment of erosion of the uterine neck, colpitis, as well as the bacterial form of vaginosis.

[3], [4], [5], [6]

Release form

Produced in pessaries for 5 pieces inside the blister. In a separate pack contains 2 blister plates.

Chlorhexidine-Health

Chlorhexidine-health is a disinfectant medicine, an antiseptic. It is produced in the form of a solution applied externally.

It is used to prevent STDs (gonorrhea, chlamydia, as well as syphilis, ureaplasmosis and trichomoniasis, genital herpes form).

The solution is also used for disinfection of infected surfaces of burns and wounds with pus. In addition, to eliminate infectious processes on the mucous membranes and skin in obstetric, surgical, urological (urethroprostatitis with urethritis), as well as gynecological and dental practices (for irrigation and rinsing with aphtha, alveolitis with gingivitis and periodontitis with stomatitis).

To disinfect small lesions (small burns, scratches and wounds).

Chlorhexidine-cr

Chlorhexidine-kr is produced in a container of 100 ml volume, equipped with a special nozzle. Inside the package - 1 container.

[7], [8], [9], [10], [11], [12]

Pharmacodynamics

Gluconate chlorhexidine has a powerful and rapid effect on such gram-negative with gram-positive microbes: pale treponemia, chlamydia, Ureaplasma spp., Gonococci and vaginal trichomonas.

Weak sensitivity to the drug is found in strains such as pseudomonas and proteas.

Resistance is possessed by bacteria of an acid-like type, fungi, bacterial spores and viruses.

[13], [14], [15], [16], [17]

Pharmacokinetics

After intravaginal administration, the drug is almost not absorbed, so it has no systemic effect.

[18], [19], [20], [21], [22],

Dosing and administration

Enter pessaries need an intravaginal method.

Mode of application: 1 pessary should be administered in the period of 7-10 days 1-2 days per day (the duration of the course depends on the nature of the pathology). If there is a need, the course is extended (maximum - 20 days).

In the prevention of STDs: administer 1 pessary one time after sexual contact (no more than 2 hours later).

During pregnancy. In view of the severity of the infection, the results of bacteriological tests, and the risk of pregnancy disruption, the drug is used on the first dose 1-2 times per day (with monotherapy or with combined treatment). Duration of use is within 5-10 days.

During lactation it is allowed to use medicines in standard recommended dosages.

[34], [35], [36], [37], [38]

Use of the chlorhexidine during pregnancy

It is allowed to use Chlorhexidine during lactation, as well as pregnancy.

Contraindications

Contraindication is intolerance of the components of the drug.

[23], [24], [25], [26], [27], [28]

Side effects of the chlorhexidine

As a result of the drug, side effects such as allergy and itching at the site of drug administration can occur.

[29], [30], [31], [32], [33]

Interactions with other drugs

It is forbidden to combine Chlorhexidine with detergents that contain anions (among them sodium lauryl sulfate with saponins, as well as sodium carboxymethylcellulose), and also combine with soap.

[39], [40]

Storage conditions

Chlorhexidine should be kept out of the reach of children. The temperature at storage ЛС - a maximum 25 ° С.

[41], [42], [43]

Shelf life

Chlorhexidine can be used in the 2 years since the manufacture of the drug.

[44]