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Cetrimide
Last reviewed: 03.07.2025

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Pharmacodynamics
A solution containing up to 10% of the substance cetrimide can be converted into a detergent. This circumstance allows the use of this medicine to eliminate the seborrheic form of dermatitis caused by Pityrosporum spp.
The shampoo has antimycotic properties (relative to Malassezia furfur), and at the same time antibacterial effect relative to gram-positive microbes. In case of increase of the concentration index of the drug, it is capable of affecting individual viruses and individual gram-negative microorganisms.
Cetrimide can act in a slightly alkaline or neutral environment. Bactericidal properties are weakened by the influence of an acidic environment, but significantly increased when combined with alcohol. As a result, the solution is used in the form of shampoo. In this dosage form, it is also used as a detergent that cleanses the skin.
All these characteristics allow us to consider Cetrimide as a first-line drug that eliminates dandruff, because it removes scales and cleanses the scalp. The antibacterial action helps eliminate viruses with microbes and bacteria.
Pharmacokinetics
Cetrimide is a 4-ammonium antiseptic drug with characteristics seen in cationic sufractants. Within an aqueous solution, the sufractants are converted into a bioactive cation, whose function is surface action, and into an anion with weaker activity.
The substance is synthesized for a long time with ketarin, as well as collagen, thus forming cetrimide protein complexes. That is why solutions with a low level of cetrimide used to treat dermatological diseases do not have significant absorption. In addition, the active properties of the drug have a very narrow scope of influence of side effects.
Use Cetrimide during pregnancy
The shampoo should not be used during lactation or by pregnant women in the first trimester.
Contraindications
Contraindications: hypersensitivity, as well as children under 1 year of age.
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Storage conditions
The shampoo should not be stored together with other medicines. Keep it out of reach of children at a low temperature.
Shelf life
Cetrimide can be used for a period of 3 years from the date of manufacture of the shampoo.
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Attention!
To simplify the perception of information, this instruction for use of the drug "Cetrimide" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.