Calcium-D3 Nycomed

Each adult person in his body contains 1-1.5 kg of calcium, 99% of which is in the skeleton. Calcium exists in free and bound form. If for any reason the stocks of free matter are depleted, it is washed out of the bones to maintain the proper level in the blood. Thanks to this, 20% of bone is renewed annually. The daily requirement for calcium is 0.8-1.2 g. Sources of mineral intake are food products such as dairy, seafood, liver, eggs, vegetables and fruits. A person would have enough calcium in them, provided it is completely absorbed. However, this is prevented by other substances: fiber, oxalic and phytic acid, potassium, magnesium and phosphorus, a deficiency or excess of fats. As a result, only up to 40% of the substance enters the body from the products. Calcium deficiency is replenished with the chemist's drug calcium-d3 nycomed, which also contains cholecalciferol.

[1], [2]

Indications of the calcium-D3 Nycomed

Indications for the use of calcium-d3 nycomed is a lack of a mineral substance that provides important functions in the life of a person or vitamin D3, which organizes its assimilation. In addition, it is used for the prevention of osteoporosis of various nature and in its complex treatment.  

[3], [4]

Release form

Calcium-d3 nycomed is available in the form of biconvex white chewable tablets, which are packed in polymer bottles with a twist cap and a ring for tearing off at the first opening. Are sold in cardboard boxes. There are tablets with two flavors. So, calcium-d3 nycomed with orange flavor in the composition of auxiliary substances contains orange oil, which gives a corresponding note when chewing. Calcium-d3 nycomed with mint flavor with mint additives. Other characteristics do not differ from each other. Packed tablets of 20, 50 and 100 pieces. Calcium d-3 nycomed forte is another packaging, in the bottle there are 30, 60 and 120 tablets. It contains the same amount of calcium as the previous ones, and cholecalciferol is twice as high as 400MM.

Pharmacodynamics

Pharmacodynamics preparation - a function of structural tissue for bones and teeth, muscle contractions, coordination of heartbeat. Calcium is also necessary for the transmission of nerve impulses, regulation of blood pressure. Promotes normal clotting of blood, enhancing the action of prothrombin. It also performs transport functions for nutrients penetrating the cell membranes. Strengthens the immune system, synthesizes and activates hormones and enzymes necessary for digestion of food and other metabolic procedures. At the same time, it reduces the production of parathyroid hormone, the main regulator of calcium metabolism, which promotes the washing out of bone tissue.

[5], [6],

Pharmacokinetics

The pharmacokinetics of calcium-d3 nycomed is determined by the property of vitamin D3, which is part of its composition, to carry out the transport function, to regulate the absorption and distribution of calcium and phosphorus in the body, in other words, to be responsible for metabolic processes. Cholecalciferol absorbed in the small intestine, and calcium - in its proximal part, while about one third of the drug is absorbed. It is excreted from the body through the urinary system, with feces, partly with sweat.  

[7], [8], [9]

Dosing and administration

The way of application and dose depends on the age of the person and the purpose of admission. So, for the prevention of children from 5 to 12 years, 1 tablet twice a day, after 12 years and adults - 3 times is shown. In the treatment of osteoporosis, 1 dose 2-3 times a day is recommended. The medicine is taken orally, regardless of the meal. It is allowed to chew, divide the pill, swallow whole. To drink, a small amount of liquid is needed. The course of treatment is determined individually, the maximum - 1,5 months. It is possible to repeat the therapy again during the year.

[12], [13], [14]

Use of the calcium-D3 Nycomed during pregnancy

Use of the drug during pregnancy is necessary because of the increased need of a woman in calcium, because to form the skeleton of a future baby, you need additional "building material". The demand for mineral matter during this period increases to 1.5 g, and in vitamin D3 - 600 MW. Indications for the appointment is a lack of calcium, manifested in the state of nails, hair: nails break and separate, hair dull, brittle, visited. Teeth deteriorate, caries develop, the calves of the legs reduce strong convulsions. Apply the remedy with the threat of miscarriage, early toxicosis, muscle tone increase. Lack of calcium also affects the fetus. There is a risk of having a physically and mentally retarded child, as well as having a diagnosis of rickets.

Contraindications

Contraindications to the use of the drug exist and concern such diseases as phenylketonuria - hereditary pathology associated with metabolic disorders of individual amino acids, the presence of kidney stones, the inability to purify the blood and excrete urine, sarcoidosis. Do not prescribe calcium-d3 nycomed to children under 5 years old and elderly, as well as with allergies to compound preparations. Contraindicated in patients with elevated levels of calcium in the blood and urine.

[10]

Side effects of the calcium-D3 Nycomed

Side effects were rare and were expressed in the occurrence of pain in the stomach, nausea, lack of appetite, stool. Sometimes there was an allergy in the form of rashes on the skin, itching. There may be hypercalcemia and hypercalciuria. 

[11],

Overdose

Overdose may occur if the recommended dose is exceeded or if the product is used for a long time. This causes weakness, dizziness, pain, malaise, coma may occur. These symptoms indicate an overabundance of the substance. Sometimes even kidney work is disrupted, which is a good reason to immediately stop taking medication, rinse the stomach with plenty of water, go on a diet that minimizes the presence of calcium in foods. A heavier condition requires specialist intervention.

[15], [16],

Interactions with other drugs

Taking calcium-d3 nycomed, one should take into account its various interactions with other drugs. It is necessary to avoid simultaneous use of it with preparations containing calcium and cholecalciferol. Carrying out therapy with antibiotics of a group of tetracyclines it is necessary to breed their reception in time of 3 hours, because their effect is enhanced. Corticosteroids weaken its absorption. In cardiac problems, if treatment is performed with cardiac glycosides, it is necessary to conduct monitoring electrocardiograms. Diuretics are capable of both increasing the calcium content in the blood (thiazide) and lowering it (looping). The therapeutic effect of vitamin D3 decreases with the parallel intake of barbiturates and phenytoin, reduce its absorption and laxatives.

[17], [18], [19], [20],

Storage conditions

Storage conditions - protected from bright sunlight, the optimum temperature range is 15-25 ⁰ C. It is also necessary to ensure unavailability for children.

[21], [22], [23], [24]

Shelf life

3 years.