Canizon

Canison has a fungistatic and fungicidal effect (their development depends on the size of the dosages used).

Indications Canizon

The cream is used to treat the following disorders and pathologies:

• mycoses affecting the epidermis, associated with microflora that is sensitive to drugs;
• mycotic lesions affecting the ears;
• fungal infections of the scalp;
• erythrasma;
• lichen of a multi-colored or pityriasis-like nature;
• mycoses, against the background of which pyoderma is diagnosed.

The tablets are used in the following situations:

• vulvovaginitis;
• superinfections in the vaginal area;
• urogenital candidiasis;
• stage of preparation for the birth process (for vaginal sanitation).

During the treatment of urethritis or infections in the genital area, a pronounced effect from the use of drugs is also observed.

The cream is recommended for use in the treatment of dermatomycosis in the area of skin folds and hairy areas of the body.

Canison is used as an adjuvant drug in the treatment of trichomoniasis (an element of general chemotherapy).

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Release form

The drug is available in the form of a cream (a tube with a volume of 20 g), a solution (a bottle with a capacity of 20 ml), and also vaginal tablets (6 pieces per plate, as well as 1 applicator per package).

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Pharmacodynamics

Dimorphic and mold fungi, as well as dermatophytes and blastomycetes with actinomycetes are sensitive to the drug.

The active element of Canison slows down the processes of binding of molecules of the component ergosterol (it is necessary for the formation of membranes of fungal cells). The disruption of the binding of this substance contributes to the destruction of cell membranes and changes in the intracellular structure. As a result, the fungal cells die.

At the same time, clotrimazole has a retarding effect on peroxidases, potentiating the activity of oxidative processes inside cells.

The medicine also has an antibacterial effect on staphylococci with corynebacteria and streptococci. In addition, it effectively affects amoebas with trichomonads.

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Pharmacokinetics

Canison has a high ability to penetrate into various layers of the epidermis. The drug does not have resorptive properties.

After intravaginal use, only a local effect is observed; a minimal amount of the active element of the drug is absorbed through the vaginal mucosa.

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Dosing and administration

Suppositories are inserted into the vagina using a special applicator. A suppository is first inserted into it, after which it is inserted deep into the vagina. After using this device, it must be washed thoroughly. The patient must remain in a lying position until the suppository has completely dissolved.

The procedure is performed 1-2 times a day. In case of a single administration of the drug per day, the procedure is recommended to be performed in the evening, before going to bed. Usually such therapy lasts 6 days; if necessary, this course can be repeated.

When diagnosing a candidal form of balanitis or vulvitis, it is necessary to combine tablets with cream, which is applied to the affected areas 2-3 times a day.

One portion of the drug solution is 10-20 drops. This dosage is applied to the epidermis or mucous membranes in the affected areas.

Scheme of using the cream.

The cream is used externally only. Every day, apply a thin layer to the infected area. Repeat this procedure 2-3 times a day. Before using the cream, clean and dry the areas that were affected by the infection.

Therapy usually lasts for 1 month. People with pityriasis versicolor should use the drug for 21 days, and people with mycosis in the area of the feet should use the cream for 14 days.

The duration of the treatment cycle is selected by the doctor on an individual basis, but it is not recommended to carry out therapy in short courses, because this may lead to a relapse of the disease in the future.

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Use Canizon during pregnancy

Although there is no information about the negative impact of the drug on the body of pregnant women, its use in the 1st and 2nd trimesters is prohibited. Before childbirth, vaginal suppositories can be used, but only with the doctor's prescription.

During breastfeeding, Canison can be used only under constant medical supervision. It is prohibited to treat the breast and nipples with the preparation.

Contraindications

Contraindicated for use in individuals with diagnosed hypersensitivity to clotrimazole or other medicinal components.

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Side effects Canizon

The use of the drug may provoke the occurrence of the following side effects:

• redness of the epidermis;
• headaches;
• a tingling or burning sensation, as well as itching;
• increased vaginal discharge;
• pain occurring in the lower abdomen;
• swelling in the mucous membranes;
• irritation of the genital mucosa after sexual intercourse.

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Interactions with other drugs

Canison weakens the therapeutic effect of amphotericin B, and in addition reduces the effectiveness of polyene antibiotics.

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Storage conditions

Canison tablets must be kept at temperatures between 15-25°C, and the cream must be kept at temperatures not exceeding 20°C.

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Shelf life

Canison can be used within 36 months from the date of manufacture of the medicinal product.

Application for children

The medicine should not be prescribed to children under 2 years of age. In the age group up to 12 years, the medicine is used with caution, strictly following the doctor's instructions.

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Analogues

Analogues of the drug are Candibene, Imidil with Triderm, and also Candid with Clotrimazole and Antifungol.

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Reviews

Canison receives positive feedback from patients who leave their comments on medical forums. They indicate that the drug demonstrates effectiveness in the treatment of dermatomycosis that occurs in the area of skin folds and hairy areas on the body.

It is also noted that the drug copes with pathologies of fungal nature and allergic dermatitis. Negative symptoms during therapy with this drug occur only occasionally.