Best vitamins for women during menopause: names

When the period of gradual fading of the reproductive function of the female body begins, in addition to the cessation of menstruation, the hormonal background changes dramatically, as a result of which many unpleasant symptoms arise. This period can last for a long time - from 1 year to 8 years, so a woman needs to take special drugs, including vitamins during menopause, which improve health and well-being.

Indications menopause vitamins

Indications for use include: vitamin deficiency, as well as estrogen hormone deficiency in the body, hot flashes, unstable psycho-emotional state.

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Release form

Pyridoxine is available in tablet form, 10 tablets per blister. The package contains 5 blister strips.

Tocopherol is available in capsules of 0.5 g. One glass jar contains 15 pcs.

What vitamins are needed during menopause? Vitamin names

To stabilize the condition during the period of decreased activity of the reproductive system, a woman needs to take the following vitamins:

• Vitamin A (or retinol) - this substance has antioxidant properties, which allows it to prevent the occurrence of tumors in the intestines and mammary glands, as well as the uterus. Retinol helps slow down aging, moisturize the skin, thereby preventing the appearance of wrinkles;
• Vitamin C is a natural antioxidant, and in addition, it acts as a preventative measure, which is necessary during the period when there is the greatest risk of tumors;
• Vitamin D promotes rapid absorption of calcium (this is very important during the period when metabolic processes begin to slow down) and prevents the development of osteoporosis due to a rapid decrease in estrogen levels;
• Vitamins of group B6 (or pyridoxine), as well as B1 (or thiamine) are agents that help normalize the function of the nervous system - they stabilize mood along with sleep, and in addition, ensure good performance.

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Vitamin E for menopause

Vitamin E is also called tocopherol. It prolongs the life of the ovaries, prolonging their life. Vitamin E during menopause helps regulate the production of estrogen together with progesterone. In addition, it reduces blood pressure and strengthens the vascular walls.

American vitamins for menopause

The Herbal Female Complex from the American company Solgar is a herbal vitamin complex that helps maintain good health and well-being in women over 40. It stabilizes hormonal levels, which is why it is used during menopause. You need to take 1-3 capsules/day. The medication is taken in courses.

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Vitamin complex for menopause

Each multivitamin complex contains the required amount of substances that are necessary for the female body during menopause. Since a huge number of such drugs are currently being produced, it is necessary to carefully approach their selection. Among the most popular are the following vitamin complexes:

• The Russian drug Extravel contains vitamins of groups B6 and E, as well as medicinal extracts (wild yam, nettle, and in addition, black cohosh and soybeans), and along with them amino acids with folic acid, as well as boron;
• German Klimadinon Uno, which contains black cohosh;
• Croatian vitamins Feminal, including red clover;
• Finnish Femicaps, containing vitamins E and B6, as well as passionflower, vitex fruit, soy lecithin, and in addition magnesium with evening primrose.

The properties of vitamins during menopause are discussed using pyridoxine as an example.

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Pharmacodynamics

Pyridoxine is a water-soluble vitamin from the B6 group, which helps to replenish the deficiency of this substance in the body, and also regulates the effect on neurotransmitters and amino acid metabolism. This substance is a coenzyme of decarboxylases with transaminases.

Pyridoxine promotes the process of glycogen breakdown in muscles (including the myocardium), and also stabilizes energy metabolism in muscles during hypoxia. Vitamin PP (or nicotinic acid) is synthesized from tryptophan, and also stabilizes the processes of cysteine, 2-aminopentanedioic acid, and methionine metabolism.

In addition, this element synthesizes neurotransmitters - dopamine and noradrenaline, as well as glycine with serotonin and GABA. Along with this, it shifts the balance of the above conductors towards the predominance of slowing ones (glycine, as well as GABA with serotonin). Pyridoxine controls excitability processes in the central nervous system and activates the activity of the antinociceptive system.

The substance promotes the process of heme synthesis within hemoglobin, increases the synthesis of siderophilin, and in addition stabilizes the processes of folic acid metabolism, as well as vitamin B12. On the surface of fibrinogen and platelets, pyridoxine binds to 2,6-diaminohexanoic acid, as a result of which blood clotting slows down, as well as platelet aggregation. As a result, blood fluidity increases, its viscosity decreases, and blood supply to cells and tissues improves.

Pyridoxine alters the effects of steroid hormones (such as androgens, glucocorticoids, estrogens, gestagens), thereby modifying the process of interaction of the cell nucleus with the hormone-receptor complex.

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Pharmacokinetics

After oral administration, pyridoxine is rapidly absorbed (in the small intestine, this occurs via passive diffusion, which is why this pathway is not considered saturable). The concentration of the substance in blood plasma is 3-18 mg/ml.

The substance moves through the circulatory system in a state associated with hemoglobin in erythrocytes, as well as albumins. In the liver, it undergoes a metabolic process, eventually turning into vitamers (pyridoxal with pyridoxine, as well as pyridoxamine). Vitamin B6 is mainly contained in skeletal muscles (about 80-90% of the total substance in the body).

The substance is excreted in the urine as inactive pyridoxine acid. The half-life is approximately 25-33 days.

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Dosing and administration

Extravel should be taken 1-2 tablets with food. The course lasts 2 months.

Klimadinon Uno is prescribed in a dosage of 2 times a day, 1 tablet, washed down with water.

Feminal is taken in a dose of 1 capsule 1 time per day, preferably before noon.

Femicaps should be taken twice a day, 2 capsules for 3 months.

Tocopherol should be taken in a dosage of 100-200 mg for 10-15 days. This course should be repeated 4-5 times a year. You should alternate the use of pure vitamin E with taking multivitamin complexes.

The drug Hypotrilon must be taken 2 times a day, 1 capsule with or after food for 1 month.

"Doppelherz Active Menopause" should be taken 1 tablet with food, washed down with water. The duration of the treatment course is 1 month.

“Woman 40+” – this vitamin complex must be taken for 1 month, 1 tablet/day.

Orthomol Femin should be taken every day, 2 capsules. The course duration is 1 month.

Vitamins "Qi-Klim" should be taken for at least 2 months, daily, in a dosage of 1 tablet/day.

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Contraindications

Pyridoxine should not be prescribed in the presence of hypersensitivity to this substance, as well as in case of terminal liver failure.

Tocopherol is not recommended for use in cases of severe cardiosclerosis, as well as in cases of thromboembolism or myocardial infarction.

Retinol is contraindicated in chronic pancreatitis, as well as cholelithiasis.

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Side effects menopause vitamins

Side effects after taking pyridoxine include allergies (anaphylactic shock is possible), as well as irritation of the gastric mucosa and pain in the stomach. In case of prolonged intake of the vitamin in a dosage of 100-200 mg/day, the so-called "pyridoxine dependence" syndrome may begin. It is accompanied by confusion, convulsions, anemia, glossitis, and seborrhea.

Tocopherol in large doses can provoke creatinuria, and in addition, diarrhea, as well as decreased performance.

Retinol can cause hypervitaminosis A, the symptoms of which are vomiting with nausea, headaches, drowsiness, fever, and peeling of the epidermis.

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Overdose

When taking pyridoxine, an overdose is possible (if you take 200-2000+ mg of the drug per day). Its manifestations are numbness in the feet and hands (a feeling of compression).

The consequences can be eliminated by discontinuing the drug, as well as by symptomatic treatment. For this purpose, galantamine or neostigmine (in small quantities) are administered to improve neuromuscular activity. There is no specific antidote.

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Interactions with other drugs

Pyridoxine reduces the neurotoxic effect of substances such as cycloserine, isoniazid, as well as hydralizine and D-penicillamine. In addition, it reduces the antiparkinsonian effect of levodopa, increasing the rate of metabolism of this substance in the liver and gastrointestinal tract, as a result of which it fails to enter the central nervous system.

Pyridoxine also helps the body absorb iron and store it in a reduced form. Increases the effect of heparin and indirect anticoagulants (such as warfarin, phenindione, and neodicumarin). Increases the analgesic properties of tramadol and metamizole, as well as nefopam and aspirin. Pyridoxine has no pharmaceutical compatibility with vitamins of groups B12 and B1.

The bioavailability of tocopherol increases in combination with selenium. Tocopherol increases the effect of indirect anticoagulants on the body. It is prohibited to combine it with drugs containing silver or iron, as well as drugs with an alkaline environment.

Tocopherol enhances the properties of anti-inflammatory drugs, reduces the toxicity of substances such as digoxin and digitoxin. It acts as an antagonist of vitamin K. Increases the effect of antiepileptic drugs on the body. The absorption of tocopherol is slowed down when combined with mineral oils.

Retinol should not be combined with other drugs containing retinoids and vitamin A to avoid the development of hypervitaminosis type A. It should also not be combined with tetracycline antibiotics. GC with salicylates help reduce the risk of side effects from taking retinol. The concentration of vitamin A in plasma increases when combined with estrogens and oral contraception.

When combined with vitamin D, the risk of developing hypervitaminosis of both types (A and D) is reduced. The absorption of retinol is interfered with by substances such as colestipol, nitrites, and in addition neomycin (internal use) and cholestyramine.

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Storage conditions

Most vitamins used during menopause should be stored in dry, dark places. The temperature should not exceed 25 ºС. They should also be stored in a place closed to children.

Retinol may be stored at temperatures no higher than +10 °C.

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Shelf life

Vitamins for menopause are generally recommended to be used within 3-4 years from the date of manufacture.

The best vitamins for menopause

Vitamins during menopause help to replenish the deficiency of useful substances and microelements. Many of these drugs are balanced complex preparations that have a systemic effect on the body. Special supplements and drugs that contain extracts from medicinal herbs, as well as phytoestrogens, are best suited.