The best vitamins for women in the menopause: the names

When the period of gradual extinction of the reproductive function of the female body begins, in addition to stopping menstruation, the hormonal background changes dramatically, resulting in many unpleasant symptoms. This period can last for a long time - from 1 year to 8 years, so a woman needs to take special medications, including vitamins in menopause, which improve health and well-being.

Indications of the vitamins in menopause

Among the indications for use: a deficiency of vitamins, as well as the hormone estrogen in the body, "hot flashes" of heat, an unstable psycho-emotional state.

[1], [2]

Release form

Pyridoxine is available in the form of tablets, 10 pcs. Each. On the blister. The package contains 5 blister plates.

Tocopherol is released in capsules with a volume of 0.5 g. One glass jar contains 15 pcs.

What vitamins are needed for menopause? Names of vitamins

To stabilize the condition during the period of decline in the activity of the reproductive system, a woman needs to consume such vitamins:

• Vitamin A (or retinol) - this substance has antioxidant properties, which allows it to prevent the occurrence of tumors in the intestines and mammary glands, as well as the uterus. Retinol allows you to slow down aging, moisturize the skin, thereby preventing wrinkles;
• Vitamin C is a natural antioxidant, and in addition it acts as a preventive agent, which is necessary at a time when there is a high risk of tumors;
• Vitamin D group promotes rapid absorption of calcium (this is very important in the period when metabolic processes begin to slow down) and prevents the occurrence of osteoporosis due to a rapid decrease in the level of estrogen;
• Vitamins B6 (or pyridoxine), as well as B1 (or thiamine) are the means to help normalize the function of the nervous system - they stabilize the mood with sleep, and also ensure good performance.

[3],

Vitamin E with menopause

Vitamin E is also called tocopherol. It prolongs the period of functioning of the ovaries, prolonging their vital functions. Vitamin E in menopause helps regulate the production of estrogen along with progesterone. In addition, it reduces blood pressure and strengthens the vascular walls.

American vitamins from menopause

The drug Herbal Female Complex from the American company Solgar is a vitamin complex on herbs that allows you to maintain good health and good health in women after 40 years. It stabilizes the hormonal background, as a result of which it is used during the menopause. It is required to drink 1-3 capsules / day. Reception of medication course.

[4], [5], [6], [7]

Complex of vitamins in menopause

In each multivitamin complex in the required amount contain substances that are necessary for the female body with menopause. Since now a huge number of such drugs are produced, it is necessary to carefully approach their selection. Among the most popular following complexes of vitamins:

• Russian drug Extrovel containing vitamins of groups B6 and E, as well as therapeutic extracts (wild yam, nettle, and in addition tsimitsifugi riccimosa and soy), and along with them amino acids with folic acid, as well as boron;
• German Climadinon Uno, which includes the cimisifugi of the racemose;
• Croatian vitamins Feminal, including red clover;
• Finnish Femikaps, containing vitamins of groups E and B6, as well as passionflower, fruits of vitex, soy lecithin, and in addition magnesium with an evening primrose.

The properties of vitamins in menopause are considered on the example of pyridoxine.

[8], [9]

Pharmacodynamics

Pyridoxine is a water-soluble vitamin from the B6 group, which helps to fill the lack of this substance in the body, and also regulates the effect on neurotransmitters and amino acid metabolism. This substance is coenzyme decarboxylase with transaminases.

Pyridoxine promotes the process of decomposition of the glycogen in the musculature (including the myocardium), and also stabilizes the energy exchange in muscles under hypoxia. Synthesized vitamin PP (or nicotinic acid) from the substance tryptophan, and also stabilizes the processes of cysteine exchange, 2-aminopentanedioic acid and methionine.

In addition, this element synthesizes neurotransmitters - dopamine and norepinephrine, and in addition glycine with serotonin and GABA. Together with this, he shifts the balance of the above conductors toward the predominance of slowing (this is glycine, and also GABA with serotonin). Pyridoxine controls the processes of excitability in the central nervous system and activates the activity of the antinociceptive system.

The substance promotes the process of heme synthesis inside hemoglobin, increases the synthesis of siderophilin, and besides it stabilizes the processes of metabolism of folic acid, as well as vitamin B12. On the surface of fibrinogen and platelets, pyridoxine binds to 2,6-diaminohexanoic acid, which leads to a decrease in blood clotting, as well as aggregation of thrombocytes. As a result, the fluidity of the blood increases, its viscosity decreases and the blood supply of cells and tissues improves.

Pyridoxine changes the effect of steroid hormones (such as androgens, glucocorticoids, estrogens, gestagens), thereby modifying the process of interaction of the cell nucleus with the hormone-receptor complex.

[10], [11], [12],

Pharmacokinetics

After ingestion, pyridoxine is rapidly absorbed (in the small intestine this occurs by passive diffusion, so this pathway is not considered saturated). The concentration of the substance in the blood plasma is 3-18 mg / ml.

The substance is transported through the circulatory system in a state associated with hemoglobin in erythrocytes, and also with albumins. In the liver, it undergoes a metabolic process, resulting in vitamers (pyridoxal with pyridoxine, as well as pyridoxamine). Vitamin B6 is mainly found in the muscles of the skeleton (about 80-90% of the total substance present in the body).

The substance is excreted in the urine under the guise of inactive pyridoxic acid. Half-life is about 25-33 days.

[13], [14], [15], [16], [17],

Dosing and administration

Extrovel should be consumed on 1-2 tablets with food. The course lasts 2 months.

Climadinone Uno is prescribed in a dosage of 2 times / day for 1 tablet and washed down with water.

Feminal is used in a dose of 1 capsule 1 time / day, it is advisable to take a reception before noon.

Femikaps need to drink twice a day for 2 capsules for 3 months.

Tocopherol must be taken in a dosage of 100-200 mg for 10-15 days. This course should be repeated 4-5 times a year. It should be alternated the use of pure vitamin E with the reception of multivitamin complexes.

The drug Hypotrilon is required to drink 2 r.az / day for 1 capsule with or after eating for 1 month.

"Doppelgerz active Menopause" should drink 1 table. Together with food, washing down with water. Duration of treatment course - 1 month.

"Woman 40+" - this complex of vitamins is required to be taken within 1 month, 1 tablet / day.

Orthomol Femin is required to take 2 capsules every day. Duration of the course is 1 month.

Vitamins "Tsi-Klim" should be drunk for at least 2 months, daily, at a dosage of 1 table / day.

[26], [27], [28], [29]

Contraindications

Pyridoxine can not be administered in the presence of hypersensitivity to this substance, as well as with liver failure in the terminal stage.

Tocopherol is not recommended for use in cases of cardiosclerosis in severe form, but also for thromboembolism or myocardial infarction.

Retinol is contraindicated in the chronic form of pancreatitis, as well as cholelithiasis.

[18], [19], [20], [21], [22]

Side effects of the vitamins in menopause

Among the adverse reactions after taking pyridoxine - allergy (possible anaphylactic shock), and in addition irritation of the gastric mucosa and pain in the stomach. In the case of prolonged intake of vitamin D at a dosage of 100-200 mg / day. The so-called "pyridoxine-dependence" syndrome may begin. With him, confusion, convulsions, anemia, glossitis, and seborrhea are observed.

Tocopherol in large doses can provoke creatinuria, and in addition diarrhea, as well as a decrease in working capacity.

Retinol can cause hypervitaminosis A, the symptoms of which are vomiting with nausea, headaches, drowsiness, fever, peeling of the epidermis.

[23], [24], [25]

Overdose

When taking pyridoxine, an overdose is possible (if you enter 200-2000 + mg of drug per day). Its manifestations are numbness in the feet and hands (compression is felt).

Elimination of the consequences can be done by canceling the medicine, as well as conducting symptomatic treatment. To do this, galantamine or neostigmine (in small amounts) is introduced to improve neuromuscular activity. There is no special antidote.

[30], [31], [32], [33], [34]

Interactions with other drugs

Pyridoxine reduces the neurotoxic effect of substances such as cycloserine, isoniazid, as well as hydralysin and D-penicillamine. In addition, it reduces the antiparkinsonian action of levodopa, increasing the rate of metabolism of this substance in the liver and gastrointestinal tract, as a result of which it can not enter the central nervous system.

Also, pyridoxine helps the body absorb iron and save it in a restored form. Increases the effect of heparin and anticoagulants of indirect action (such as warfarin, phenindione, and neodicumarin). Increases the analgesic properties of tramadol and metamizole, and in addition to nefopam and aspirin. Pyridoxine has no pharmaceutical compatibility with the vitamins of groups B12 and B1.

Bioavailability of tocopherol increases in combination with selenium. Tocopherol increases the effect on the body of indirect anticoagulants. It is forbidden to combine it with drugs containing silver or iron, as well as drugs with an alkaline medium.

Tocopherol enhances the properties of anti-inflammatory drugs, reduces the toxicity of substances such as digoxin and digitoxin. Acts as a vitamin K antagonist. Increases the effect on the body of antiepileptic drugs. Absorption of tocopherol slows down when combined with mineral oils.

Retinol can not be combined with other drugs that contain retinoids and vitamin A to prevent the development of hypervitaminosis type A. You can not also combine tetracycline antibiotics. GK with salicylates help to reduce the risk of adverse reactions from taking retinol. The concentration of vitamin A in plasma is increased when combined with estrogen and oral contraception.

When combined with a vitamin D group, the risk of developing hypervitaminosis of both types (A and D) decreases. Absorption of retinol is prevented by substances such as colestipol, nitrites, and in addition neomycin (internal reception) and colestyramine.

[35], [36], [37], [38], [39]

Storage conditions

Most vitamins used in menopause should be kept in places that are closed from light and dry. The temperature should not exceed 25 ° C. They must also be stored in a place that is closed to children.

Retinol is allowed to store in conditions no more than +10 ° С.

[40], [41], [42], [43]

Shelf life

Vitamins in menopause are generally recommended for use within 3-4 years from the date of manufacture.

The best vitamins for menopause

Vitamins in menopause allow us to fill the deficiency of nutrients and microelements. Many of these drugs are balanced complex drugs that have a systemic effect on the body. The best additives are special supplements and medicines that contain extracts and extracts from medicinal herbs, as well as phytoestrogens.