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Last reviewed: 01.06.2018

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Benzonal is an anticonvulsant. It is classified as barbiturates and their derivatives.

trusted-source[1], [2], [3], [4], [5], [6], [7]

Indications of the benzonal

It is used for the treatment of epilepsy of various types.

Helps to eliminate epileptic seizures of polymorphic or non-convulsive type (it is used in combination with other anticonvulsants - diphenin, as well as carbamazepine and hexamidine).

In addition, it is an integral component of combined treatment of hemolytic pathology in newborns.

trusted-source[8], [9], [10], [11], [12]

Release form

Release in tablets with a volume of 0.05 or 0.1 g. Within the blister contains 30 tablets with a volume of 0.05 g. In the package there is 1 blister plate. Tablets of 0.1 g are available in 50 pieces inside a blister plate. In a pack - 1 such blister.

trusted-source[13], [14], [15], [16], [17], [18]


The medicine has anticonvulsant properties. Acts as an inducer of enzymes, and also enhances the activity of the monooxygenase liver system of enzymes. The hypnotic effect almost does not turn out.

trusted-source[19], [20], [21], [22], [23], [24]


Benzonal undergoes rapid metabolism inside the body, during which the substance is released phenobarbital, which has an anticonvulsant effect. With plasma protein is synthesized weakly.

The substance is distributed in equal quantities within different tissues and organs. Passes through the hematoparenchymal barrier and penetrates into the mother's milk. The process of releasing the component is rather slow. Metabolism occurs with the help of microsomal enzymes. Has the ability to cumulate inside the body. The half-life is 3-4 days.

Excretion is carried out by the kidneys, the substance is excreted as unchanged, and in the form of decay products.

trusted-source[25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]

Use of the benzonal during pregnancy

The medicine can not be prescribed during pregnancy (at the 1st and 3rd trimester), and also during lactation.


Among the contraindications:

  • the presence of increased sensitivity with respect to the components of drugs;
  • diabetes;
  • parenchymal diseases of the liver in a severe degree;
  • kidney pathologies, in which their functional disorder is observed;
  • decompensation in the work of the heart;
  • state of depression.

trusted-source[36], [37]

Side effects of the benzonal

Use of the medicine can cause such side effects: tolerance to Benzonal, drug dependence, a feeling of drowsiness and lethargy, headaches, problems with speech or gait, worsening of hearing and allergy.

trusted-source[38], [39], [40], [41], [42], [43], [44]

Dosing and administration

Benzonal used orally after eating. The course of therapy begins with a minimal single dose, with a gradual (every 2-3 days) increase until the required size of the daily dosage is reached. If sustained compensation is observed, it is necessary to gradually reduce the dose until a single daily dosage is obtained. If the seizures return, you need to restore the optimal daily dose.

The dosage is prescribed by the doctor, taking into account the patient's health condition: the adult single dose is 0.1-0.2 g and the daily dosage is 0.8 g. The maximum adult doses are: single-dose 0.3 g, daily - no more than 1 The therapeutic course lasts a long time and is continuous.

The daily dose for newborns is 5.9 mg / kg. Prescribe babies medicine with caution. To take children under 3 years old, it is necessary to powder the required number of tablets, then dissolve it in water and use it as a suspension.

Baby dosage:

  • single for 3-6 years - 0.025-0.05 g (for a day it is required to take within the limits of 0.1-0.15 g of the drug);
  • for 7-10 years - 0.05-0.1 g (per day within the limits of 0.15-0.3 g of drugs);
  • for 11-14 years - 0.1 g (per day about 0.3-0.4 g of drugs).

Maximum infantile doses (at the older age): single - 0.15 g, daily - 0.45 g.

trusted-source[45], [46], [47], [48], [49]


Manifestations of an overdose - the development of nystagmus or ataxia, or speech disorder.

To eliminate the violations, you should reduce the dosage of drugs or take caffeine (in a dosage of 0.05-0.075 g for 1 reception).

trusted-source[50], [51], [52], [53]

Interactions with other drugs

Benzobital potentiates the properties of anesthetics, analgesics, neuroleptics with hypnotics, alcoholic beverages, and tranquilizers and medicines for general anesthesia.

The drug also reduces the effects of anticoagulants with griseofulvin, tetracyclines, quinidine and paracetamol, and in addition xanthines with glucocorticoids and calciferol with cardiac glycosides.

trusted-source[54], [55], [56], [57], [58], [59]

Storage conditions

Benzonal is required to contain in a place where sunlight and moisture do not penetrate, and also inaccessible to children. The temperature is between 15-25 ° C.

trusted-source[60], [61], [62], [63], [64], [65]

Shelf life

Benzonal can be used in the period of 4 years from the date of release of the medicine.

trusted-source[66], [67], [68]

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To simplify the perception of information, this instruction for use of the drug "Benzonal" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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