Apilac

Royal jelly, also known as "apilak", is a highly valuable nutrient produced by bees in special glands in their heads. It serves as food for young bee larvae and is a key nutrient and stimulant for the development and growth of queen bees.

Royal jelly contains many biologically active components, such as proteins, amino acids, vitamins, minerals, hormones and enzymes. Due to its unique composition and high biological activity, royal jelly is widely used in the food and cosmetic industries, as well as in medicine.

In medical practice, royal jelly is often used as a dietary supplement (DS), usually in the form of a liquid extract, capsules or tablets. It is credited with various beneficial properties, such as strengthening the immune system, reducing stress and fatigue, maintaining the health of the female reproductive system and improving the condition of the skin and hair.

Despite its widespread use and popularity, it is important to remember that scientific evidence on the long-term effects and safety of royal jelly is not always clear, and it is recommended to consult a physician before using it for medicinal purposes.

Indications Apilaka

• Strengthening the immune system: Royal jelly may help strengthen the immune system, which can be especially helpful during times of increased risk of illness, such as during flu or cold season.
• Stress and Fatigue: Many people use royal jelly as a natural adaptogen to reduce stress and fatigue, as well as improve overall well-being and stamina.
• Increased Energy and Vitality: Some people take royal jelly to increase energy and vitality, especially during times of physical and mental stress.
• Supports reproductive health: In women, royal jelly may help support reproductive health, including stimulating ovulation and normalizing the menstrual cycle.
• Improvement of skin and hair condition: Royal jelly can be used for cosmetic purposes to improve the condition of skin, hair and nails due to its nutritional properties.
• Maintaining Thyroid Health: Some studies suggest that royal jelly may help maintain healthy thyroid function.
• Supporting General Health and Wellness: Royal Jelly is often taken as a supplement to support general health and wellness.

Release form

Royal jelly is available in capsule or tablet form for ease of administration.

Pharmacodynamics

• Boosting the immune system: Some studies suggest that royal jelly may help strengthen the immune system and protect the body from infections.
• Anti-inflammatory effects: The bioactive compounds in royal jelly may help reduce inflammation in the body.
• Stimulation of growth and development: Some components of royal jelly, particularly growth factors, may promote cell growth and development.
• Adaptogenic properties: Royal jelly is sometimes considered an adaptogen, which can help the body cope with stress and fatigue.
• Supports reproductive health: Some studies suggest that royal jelly may have positive effects on the reproductive system, improving fertility in women.

Pharmacokinetics

Generally accepted information about royal jelly indicates that its active components, such as proteins, amino acids, vitamins and trace elements, can be easily absorbed by the body. They usually enter the bloodstream through the digestive tract and are then distributed to tissues and organs.

Dosing and administration

It is generally recommended to take 1-2 tablets (usually 500 mg) once or twice daily with meals.

Use Apilaka during pregnancy

1. Strengthening the immune system:

   • Royal jelly has immunomodulatory properties, making it useful for strengthening the immune system and increasing the body's resistance to infections (Bălan et al., 2020).

2. Anti-inflammatory action:

   • Research shows that royal jelly has significant anti-inflammatory effects, which may be useful in reducing inflammation in the body (Fratini et al., 2016).

3. Antioxidant action:

   • Royal jelly contains powerful antioxidants that help protect cells from oxidative stress and free radical damage (Viuda‐Martos et al., 2017).

4. Estrogenic effects:

   • Royal jelly exhibits weak estrogenic effects, which may be beneficial for postmenopausal women by helping to reduce symptoms associated with estrogen deficiency (Mishima et al., 2005).

5. Support of reproductive function:

   • Royal jelly can improve reproductive parameters and fertility in animals, suggesting its potential benefit for improving reproductive health in humans (Abdelnour et al., 2020).

6. Skin benefits:

   • Royal jelly has regenerative properties, making it useful for wound healing and improving skin condition (Lin et al., 2020).

Despite the positive effects of royal jelly, pregnant women should consult a physician before using royal jelly to assess the potential risks and benefits.

Contraindications

• Allergic reaction: People with allergies to bee products such as honey or bee venom may also experience an allergic reaction to royal jelly.
• Pregnancy and breastfeeding: To avoid any negative impact on the developing fetus or child, and due to insufficient data on the effects of royal jelly during pregnancy or lactation, it is not recommended to take it during this period without consulting a doctor.
• Health Concerns: People with serious health problems, such as certain types of cancer, thyroid disease, or other chronic illnesses, may need to avoid taking royal jelly due to its effects on the body.
• Individual intolerance: Some people may experience unpleasant symptoms such as diarrhea, nausea or allergic reactions due to individual intolerance to royal jelly.

Side effects Apilaka

• Allergic reactions: Include itching, skin rash, skin redness or swelling, especially in those who are allergic to bee products.
• Gastrointestinal problems: Some people may experience diarrhea, nausea, or vomiting.
• Headaches: Some people may experience headaches after taking royal jelly.
• Possible effects on hormonal levels: Although not a common side effect, some people may experience changes in hormonal levels with long-term use of royal jelly.
• Other rare symptoms: May include fatigue, irritability, or insomnia.

Overdose

• Gastrointestinal disorders: Such as diarrhea, nausea or vomiting.
• Allergic reactions: Increased allergic symptoms such as itching, skin rash or swelling.
• Headaches: Headaches or migraines may occur.
• General malaise: Symptoms such as fatigue, irritability, or insomnia may occur.

Interactions with other drugs

• Anticoagulants (medicines that reduce blood clotting): Royal jelly may increase the risk of bleeding when taken with anticoagulants. This is due to its effect on blood clotting.
• Blood sugar lowering drugs (hypoglycemic agents): Royal jelly may affect blood sugar levels, so caution should be exercised when taken with hypoglycemic drugs to avoid hypoglycemia or hyperglycemia.
• Blood pressure lowering drugs (antihypertensives): Royal jelly may affect blood pressure and should be used with caution in combination with antihypertensive drugs.
• Hormonal imbalance medications: Because royal jelly contains hormones, its use in combination with medications that affect hormonal balance may alter the effectiveness and safety of the treatment.

Storage conditions

Store in a dry place at temperatures below 25°C, away from direct sunlight and humidity.