Anti-Angin Formula

"Anti-Angin Formula" is a medicine used to treat throat diseases such as tonsillitis and pharyngitis. Its composition includes the following active ingredients:

1. Chlorhexidine digluconate is an antiseptic that has bactericidal and bacteriostatic action. It destroys microbes, including bacteria and fungi, that can cause throat infections.
2. Tetracaine hydrochloride is a local anesthetic that can help relieve throat pain and discomfort associated with inflammation.
3. Ascorbic acid (vitamin C) - has antioxidant properties and helps strengthen the immune system, which can help fight infections and speed up the healing process.

"Anti-Angin Formula" is often used to treat symptoms of throat diseases such as pain, itching, irritation, redness and swelling.

Indications Anti-Angin Formula

1. Sore throat (acute tonsillitis): The drug can be used for the symptomatic treatment of sore throat, including sore throat, itching, irritation and discomfort.
2. Pharyngitis: It can also be used for inflammation of the back of the throat (pharyngitis) associated with infection.
3. Stomatitis: The drug may be effective in the treatment of stomatitis - inflammation of the oral mucosa.
4. Gingivitis: In some cases, Anti-Angin Formula can be used for the symptomatic treatment of gingivitis - inflammation of the gums.
5. Toothache: Also used for temporary relief of pain associated with gum or dental disease.

Release form

The drug "Anti-Angin Formula" is available in several forms:

1. Spray: The product can be a spray for the mouth and throat. The spray allows the active ingredients to be evenly distributed over the mucous membrane of the throat for rapid relief of symptoms.
2. Tablets or Pastilles: Anti-Angin Formula may also be available in the form of tablets or pastilles to dissolve in the mouth. This form of release provides local action of the active ingredients on the mucous membrane of the throat.

The choice between these forms of release may depend on the patient's preferences, age, individual characteristics and type of disease.

Pharmacodynamics

1. Chlorhexidine digluconate: This is a powerful antiseptic that is bactericidal and bacteriostatic. It is effective against a wide range of microorganisms, including bacteria and fungi that can cause infections in the mouth and throat.
2. Tetracaine hydrochloride: This is a local anesthetic that helps reduce pain and discomfort in the throat associated with inflammation. It blocks the conduction of nerve impulses in the area of application, resulting in temporary pain relief.
3. Ascorbic acid (vitamin C): Is an antioxidant and plays an important role in the functioning of the immune system. Its presence in the preparation can help strengthen the immune system and promote faster recovery from infections in the mouth and throat.

The overall effect of Anti-Angin Formula is to alleviate the symptoms of throat diseases such as pain, itching, irritation and discomfort, as well as to combat possible infection due to the antiseptic action of chlorhexidine.

Pharmacokinetics

For spray:

• Absorption: Active ingredients are absorbed through the mucous membranes of the mouth and throat.
• Distribution: They can spread along the mucous membrane and provide local action in the area of inflammation.
• Metabolism and excretion: Substances can be metabolized in tissues and excreted from the body via the kidneys or liver.

For tablets or lozenges:

• Absorption: Active ingredients are absorbed through the oral mucosa when dissolved.
• Distribution: They can also be distributed throughout the mucous membranes of the mouth and throat.
• Metabolism and excretion: Metabolism and excretion processes may occur depending on the characteristics of each active component.

Dosing and administration

1. Spray:

   • Shake the bottle before use.
   • Point the spray towards your mouth.
   • Press the sprayer to dispense one dose of medication.
   • Spray onto the back of the throat and tonsils.
   • Repeat the procedure if necessary, according to the instructions on the package or your doctor's recommendations.
   • It is generally recommended to apply the spray 2-3 times a day.

2. Tablets or lozenges:

   • Take one tablet or lozenge by dissolving it in your mouth as needed.
   • It is generally recommended to dissolve the tablet or lozenge every 2-3 hours throughout the day.
   • Follow the directions on the package or your doctor's recommendations for the length of treatment.

Use Anti-Angin Formula during pregnancy

1. Chlorhexidine diacetate:

   • Chlorhexidine is a potent antiseptic used to disinfect skin and mucous membranes. Studies have shown that topical chlorhexidine is safe to use during pregnancy. Vaginal chlorhexidine during labor may reduce bacterial load and prevent transmission of infections from mother to child. However, there are no data on systemic toxicity or effects on the fetus at standard doses (Goldenberg et al., 2006).

2. Tetracaine hydrochloride:

   • Tetracaine is a local anesthetic and its effects on pregnant women and the fetus have not been well studied. It is known that local anesthetics can cross the placenta and could theoretically affect the fetus. However, topical use in small doses is generally considered safe. It is necessary to consult a physician before using tetracaine products during pregnancy (Chapman et al., 2012).

3. Ascorbic acid:

   • Ascorbic acid (vitamin C) is widely used as a supplement and is considered safe for pregnant women when taken in recommended doses. Ascorbic acid is involved in collagen synthesis, immune system function, and as an antioxidant. It does not pose a risk to the fetus and is widely used in various dosage forms (Shiri et al., 2017).

Contraindications

1. Individual intolerance: People with known allergies or sensitivity to any of the components of the drug should avoid using it.
2. Kidney problems: Patients with severe kidney problems may need to exercise caution when using Anti-Angin Formula, especially if the drug contains active ingredients that may be metabolized or excreted through the kidneys.
3. Problems with liver function: Active components can be metabolized in the liver, so in the presence of severe liver diseases, the use of Anti-Angin Formula may be undesirable.
4. Children's age: Some forms of release may have age restrictions. For example, a spray may not be recommended for children under a certain age.
5. Pregnancy and breastfeeding: Before using "Anti-Angin Formula" during pregnancy or breastfeeding, you should consult a doctor.
6. Serious Diseases or Conditions: Patients with serious diseases or conditions such as cardiovascular disease, epilepsy or hypertension may also require special caution when using Anti-Angin Formula.

Side effects Anti-Angin Formula

1. Allergic reactions: Various allergic reactions such as skin rash, itching, hives or anaphylactic shock are possible.
2. Mucous membrane reactions: Irritation of the mucous membranes of the mouth and throat, dryness, redness or burning may occur.
3. Unpleasant taste: Some patients may experience an unpleasant taste after using the drug.
4. Dyspeptic symptoms: In rare cases, dyspeptic disorders such as nausea or vomiting may occur.
5. Throat discomfort: Temporary numbness or tingling in the throat area may occur.
6. Dry mouth: With prolonged use of "Anti-Angin Formula" dry mouth may occur.
7. Changes in sensitivity: Some patients may experience temporary changes in sensitivity in the area where the drug is applied.

Overdose

Symptoms of overdose may include increased side effects such as allergic reactions, irritation of the mucous membranes, nausea, vomiting, headache, etc.

Interactions with other drugs

1. Other antiseptics for the mouth and throat: Using "Anti-Angin Formula" simultaneously with other antiseptics may lead to an increased effect or an increased risk of side effects.
2. Local anesthetics: Using Anti-Angin Formula with other local anesthetics may enhance their effect, which may lead to discomfort or decreased sensitivity in the throat area.
3. Systemic antibiotics: The use of Anti-Angin Formula in combination with systemic antibiotics may reduce the effectiveness of antibiotics or increase side effects.
4. Medicines that affect blood clotting: Interaction with aspirin or other medicines that affect blood clotting may increase the risk of bleeding with long-term use.
5. Drugs affecting the gastrointestinal tract: Using Anti-Angin Formula in combination with drugs affecting the gastrointestinal tract (eg, antihistamines or drugs for the treatment of peptic ulcers) may increase the risk of irritation of the mucous membrane or worsening of symptoms.