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Health

Analyzes for hormones

Functional state of hormonal regulation of the reproductive system

The reproductive system consists of certain structures of the hypothalamus and pituitary gland, gonads, target organs (uterine tubes, uterus, etc.). Elements of the reproductive system are interconnected by information signals, allowing it to function as a single whole.

Estimation of the hormonal status of the thyroid gland

Estimation of hormonal status of the thyroid gland allows revealing its three functional statuses: hyperfunction, hypofunction and euthyroid status. The definition of a thyroid-stimulating hormone in conjunction with cT4 is one of the leading "strategic" markers in assessing the hormonal status of the thyroid gland.

Thyroxin-binding globulin in the blood

Thyroxin-binding globulin binds the bulk of T3 (80%) (the remaining 20% are transported by albumin and prealbumin - 10% each) and T4 (75%). 10% of T4 binds albumin, 15% of prealbumin.

Thyroglobulin in the blood

Thyroglobulin, the precursor of thyroid hormones T3 and T4, is used as a marker of tumors in the thyroid gland, and in patients with a distant thyroid gland or treated with radioactive iodine, to evaluate the effectiveness of the treatment.

Free thyroxine in the blood

On сT4 (thyroxine) accounts for 0.03% of its total amount in the blood. With the normal functioning of the thyroid gland, the mechanisms that regulate its function work in such a way that the content of cT4 (thyroxine) does not depend on the concentration of TSH.

Free triiodothyronine in the blood

On cT3 it is 0.3% of its total amount in the blood. The fraction cT3 provides the entire spectrum of metabolic activity. ST3 is a product of the metabolic transformation of T4 outside the thyroid gland.

Total thyroxin in the blood

T4 (thyroxine) - the main hormone of the thyroid gland. Its concentration in the blood exceeds that of T3 by 60 times. The elimination half-life is 5-7 days.

Total triiodothyronine in blood

T3 (triiodothyronine) is formed and synthesized by the thyroid gland, but the bulk of T3 is formed outside the thyroid gland when deaoding T4. Approximately 99.5% of T3 circulating in the blood is bound to proteins. The half-life of blood is 24-36 hours. The activity of T3 is 3-5 times higher than that of T4.

The causes of increase and decrease in thyroid-stimulating hormone

With hypothyroidism, the thyroid-stimulating hormone concentration rises. The diagnosis is confirmed by low concentrations of free thyroxine (cT4), T4, T3 in the blood. In cases of subclinical mild hypothyroidism, when the level of cT4 and T4 in the blood is within the normal range, the detection of an elevated thyroid-stimulating hormone becomes crucial.

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