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Thyroglobulin in the blood

 
, medical expert
Last reviewed: 05.07.2025
 
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Reference values (norm) for thyroglobulin concentration in blood serum are 3-42 ng/ml (mcg/l).

Thyroglobulin is a precursor of thyroid hormones T3 and T4, used as a marker of neoplasms in the thyroid gland, and in patients with a removed thyroid gland or treated with radioactive iodine, to assess the effectiveness of the treatment. Relapses of benign and malignant tumors of the thyroid gland are accompanied by an increase in the concentration of thyroglobulin in the blood in most patients. The concentration of thyroglobulin is increased in patients with subacute thyroiditis, as well as in patients with relapses of chronic nonspecific thyroiditis.

Diseases and conditions in which the concentration of thyroglobulin in the blood serum changes

Thyroglobulin is elevated

Thyroglobulin is reduced

Thyroid tumors

Subacute thyroiditis

Thyroid adenoma

Hyperthyroidism

Thyroid cancer metastases

Endemic goiter

Iodine deficiency

Graves' disease

Condition after treatment with radioactive iodine

Thyroid hormone overdose

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