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Senile keratoma

 
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Last reviewed: 04.07.2025
 
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Senile keratosis is an age-related benign change in the skin in elderly people, which manifests itself in the form of pigmented rounded lesions up to several centimeters in diameter, which are covered with layers of horny epithelium. Senile keratosis lesions are most often located on the skin of the face, neck, hands and forearms. Sometimes malignant transformation of lesions into skin cancer is possible.

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Pathogenesis

Histological examination reveals hyperkeratosis with outgrowths extending into the depths, and pronounced acanthosis. The proliferating strands consist of cells of the spinous layer of the epidermis, but small cells with dark nuclei are also encountered.

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Symptoms senile keratoma

On exposed areas of the skin (face, neck, upper limbs) solitary or multiple lesions appear. First, erythematous spots appear, then limited hyperkeratosis develops in these areas. After the forced rejection of scales, pinpoint hemorrhages are formed. Scales invariably reappear and become dense.

Over time, protruding formations develop - dense plaques 1-1.5 cm in diameter, dark in color, round in shape, covered with tightly seated gray crusts. With prolonged trauma (scratches, insolation) or irrational treatment, they can become malignant in spinalioma or basalioma.

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Differential diagnosis

Senile keratoma should be differentiated from verruca vulgaris, Bowen's disease, seborrheic keratosis, keratopapilloma, actinic keratosis, cutaneous horn, keratoacanthoma, eccrine poroma, follicular keratoma.

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Treatment senile keratoma

Therapy of senile keratoses is a method of cancer prevention. Patients should be registered with a dispensary and undergo examination once every 6 months. Long-term intake of vitamin A in large doses gives good results. At an early stage, electrocoagulation, carbonic acid snow, liquid nitrogen, 25% podophyllin ointment, 5% fluorouracil ointment are recommended; if degeneration is suspected - surgical removal, as with epithelioma, with the capture of surrounding healthy skin; X-ray therapy.

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