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Spontaneous reaction of blast transformation of lymphocytes
The magnitude of spontaneous blast transformation of lymphocytes in adults is normal - up to 10%.
Spontaneous blast transformation of lymphocytes is the ability of lymphocytes to transform without stimulation. The study is performed to evaluate the functional activity of T lymphocytes.
Diseases and conditions in which spontaneous blast transformation of lymphocytes changes
Increase in the
- Hyperactivity of the immune system in allergic and autoimmune diseases
- Activation of antigraft implantation immunity
- The crisis of rejection of donor organs
- Acute period of primary infection
- Immune response to thymus-dependent antigens
Decrease in the indicator
- Oncological diseases
- Secondary immunodeficiency states
- Congenital defects of the immune system, HIV infection
- Severe viral infections
- Heavy burns, injuries
- Treatment with cytostatics and immunosuppressants
- Ionizing radiation
- Admission of glucocorticosteroids
Alexey Portnov, medical expert
Last reviewed: 31.05.2018
Last reviewed: 31.05.2018