Inhalation with Budesonide Nativ for children and adults: dosages, recipes

Many drugs with anti-inflammatory, expectorant and antihistamine properties are suitable for inhalation use. Of the corticosteroid drugs, Budesonide is most often used for inhalation: it is actively prescribed for the treatment of Crohn's disease, as well as for bronchial asthma or pulmonary obstruction. Budesonide is a strong inhalation agent, so it must be used very carefully, strictly following the instructions provided.

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Indications for the procedure

If Budesonide is prescribed for inhalation, it means that there are certain indications for this. Such indications may be:

• Bronchial asthma.

Inhalations of Budesonide help eliminate swelling of the mucous tissues lining the inner surface of the bronchi. Thanks to the drug, the formation of sputum secretions decreases: the bronchial lumen is cleared, so after the procedure, the patient can breathe easier. In the acute period of bronchial asthma or in severe cases of the disease, Budesonide is not used for inhalations, since its antispasmodic activity is insufficient during these periods. The drug is more suitable for eliminating mild and moderate asthmatic conditions.

• Chronic form of bronchitis.

Chronic inflammation of the bronchi is characterized by excessive accumulation of sputum mucus and tissue edema. In such a situation, inhalation budesonide quickly stops the development of the inflammatory process and improves air circulation in the bronchial lumen. The treatment regimen for chronic pathology should include, in addition to budesonide, antibiotics and expectorants.

• Bronchiectatic disease.

Bronchiectasis is the expansion of limited bronchial areas, and bronchiectatic disease is an inflammatory lesion of the bronchi, which is accompanied by the appearance of bronchiectasis and the formation of mucous and purulent secretions released with coughing. Inhalations with Budesonide will help to quickly improve well-being and stop the development of an inflammatory reaction.

In case of infectious lung lesions, in case of severe bilateral pneumonia, specialists advise using more powerful medications for inhalation in combination with antibiotic therapy.

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Preparation

Budesonide, which is used for inhalation, is classified as a synthetic glucocorticoid. This drug is used locally, since in therapeutic doses it has antiallergic, immunosuppressive, anti-inflammatory properties.

The drug successfully eliminates bronchial spasms and serves as an excellent preventative measure against exacerbations.

Currently, a number of medicinal forms of Budesonide are known:

• Budesonide-native in the form of a transparent yellowish inhalation solution, in addition to the active ingredient budesonide, also contains other substances such as succinic acid, macrogol, nipagin. This solution is not used for inhalation in children under sixteen years of age.
• Budesonide Easyhaler in the form of an inhalation powder consisting of budesonide and lactose monohydrate. The powder is used only in adult practice.
• Pulmicort budesonide in the form of a dosed suspension, contains 250-500 mcg of the active ingredient. Pulmicort is used to make a solution or as an aerosol (is produced directly in aerosol inhalers).
• Budenide Steri-Neb is also a white suspension, produced in specific small polyethylene ampoules, as well as in the form of a spray. The composition of the suspension is represented by citric acid, chloride and sodium citrate. One milliliter of the drug may contain 0.25-0.5 mg of budesonide.

Budesonide-based capsules and tablets (for example, Budenofalk) are not used for inhalation. Such drugs are intended exclusively for oral administration: they are prescribed for intestinal diseases.

No special preparation is required for the Budesonide inhalation procedure. It is enough to prepare a dry and clean nebulizer and the drug itself. It is better to inhale between meals, in a sitting position, taking a comfortable body position.

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Technique Budesonide inhalation

Budesonide is used only for inhalation using a compressor inhalation device - a nebulizer. The standard therapeutic dose of the drug for an adult patient is 1-2 mg / day. The dosage can be changed at the discretion of the attending physician. We must not forget that one milliliter of solution can contain a different amount of the active ingredient, so before using the drug, you must clarify this point in the description of the drug.

Before diluting Budesonide for inhalation, you need to consult a doctor. The fact is that in case of bronchial asthma or bronchiectasis, it is preferable to use an undiluted, concentrated drug, but in doses strictly determined by the doctor. If you have to dilute the product, then do it as follows: the required amount of the product is poured into a separate container in the inhaler using a syringe, and only then 1-2 ml of sodium chloride is added to it. The resulting Budesonide solution for inhalation should be used within twenty minutes after dilution.

One inhalation should be continued for about five or ten minutes, and at the end you need to rinse your mouth with plain water (to prevent the development of fungal stomatitis under the influence of Budesonide). It is also necessary to regularly clean and rinse the nebulizer.

Budesonide for inhalation is not always suitable for children: it is usually used starting from the age of sixteen. However, one of the drugs that contains budesonide can be used from the age of six months: we are talking about Pulmicort. The drug must be diluted with saline (depending on the doctor's prescription - 1-4 ml of the drug and 1-2 ml of saline). Children from six months of age are recommended to use about 1-2 ml of Pulmicort per day (0.25-0.5 mg, but not more than 2 mg budesonide per day). An amount of the drug not exceeding 1 mg can be used by inhalation at one time.

Contraindications to the procedure

Budesonide should not be used for inhalation if there is drug hypersensitivity of the body, as well as a tendency to allergy to this drug.

Other important contraindications are:

• open form of tuberculosis, chronic course with complications;
• mycotic infection of the respiratory system (in case of mycoses, the use of Budesonide for inhalation is permitted only in combination with the injection of antifungal drugs);
• the period of bearing and breastfeeding a child (possible negative impact on the central nervous system and cardiovascular system of the baby);
• any stage of liver cirrhosis (the risk of intoxication of the body increases significantly).

If the doctor discovers any of the contraindications to prescribing Budesonide for inhalation, the drug is replaced by another one that is more suitable in a specific situation.

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Consequences after the procedure

Any unpleasant consequences after inhalation of Budesonide are rare, but you need to know about them before starting the procedures. Doctors do not exclude the appearance of such transient symptoms:

• dryness of the oral mucosa;
• the appearance of wheezing, a slight change in voice;
• headache, sensation of noise;
• food intolerance, nausea (sometimes with vomiting);
• activation of fungal infection, fungal stomatitis;
• dysfunction of the adrenal cortex (with prolonged or too frequent inhalation of Budesonide);
• drop in blood sugar levels;
• changes in blood pressure readings.

If unpleasant symptoms occur during inhalation, it is better to inform the doctor about it. Perhaps such a reaction is associated with individual sensitivity to the drug Budesonide: in such a situation, it is better to cancel the drug or replace it with a drug with a similar effect, but a different active ingredient.

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Complications after the procedure

Budesonide for inhalation is not intended for rapid relief of an acute attack of bronchial asthma, in which inhalation of short-acting bronchodilators is usually used. If during treatment with such drugs there is no positive therapeutic effect, or in case of the need for more frequent and longer inhalations than is permissible, then urgent medical intervention is necessary: the use of Budesonide in such a situation is inappropriate.

If Budesonide is used for a long course of inhalations in children, it is necessary to conduct growth monitoring regularly. In case of growth retardation, growth retardation, the treatment regimen is reviewed and the child is transferred, if possible, to a smaller amount of the drug. The benefits of Budesonide inhalations should be related to the possible risks of the child's growth retardation. To avoid complications, it is necessary to systematically consult with a pediatric pulmonologist.

Pregnant and breastfeeding patients should avoid inhalations with Budesonide. However, in cases where this drug cannot be avoided, preference is given to its inhalation administration rather than oral administration (due to the lower systemic effect of the drug).

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Care after the procedure

After inhalation with Budesonide, the patient should rinse the mouth thoroughly with clean water (to prevent the development of a fungal infection) and also wash his hands.

Next, you should disassemble the nebulizer, rinse it with running water, then with detergent and again with water. To avoid the spread of infection in the device, it must be thoroughly dried.

Approximately once a week, the inhalation device should be disinfected: boiled (if the manufacturer allows it) or placed in a special sterilizer.

After inhalation, the clean and dried nebulizer is stored in a paper package or a dry towel, in a clean, dry place, in a disassembled state. The device is assembled only immediately before use.

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Reviews

There have been numerous positive reviews regarding the short-term use of Budesonide for inhalation in adult patients. Before starting treatment, you should read some warnings:

• Budesonide is not compatible with alcohol, so you should forget about alcoholic beverages during the course of inhalations.
• Be careful not to let the solution or powder come into contact with the mucous membrane of the eye.
• Budesonide inhalations for a child should be combined with regular monitoring of his growth activity.
• Do not forget to rinse your mouth with water after completing the inhalation procedure.
• If for various reasons the patient missed the Budesonide inhalation procedure, it should be carried out as soon as possible, and the remainder of the daily dose should be used until the end of the day at equal intervals.
• It is important to store budesonide correctly, otherwise it will lose its medicinal properties. The drug should not be exposed to sunlight or high temperatures, and it should not be frozen.
• Budesonide should not be discontinued abruptly. After the end of treatment, the patient should visit the attending physician for some time to monitor the period of drug withdrawal.

Doctors note that with long-term treatment with large doses of Budesonide, the development of systemic problems cannot be ruled out, which is associated with the hormonal activity of the drug. We are talking about hypercorticism, suppression of the hypothalamus-pituitary-adrenal system. In no case should inhalations of corticosteroids (in particular, Budesonide) be practiced without a doctor's prescription. Despite the existence of a standard dosage, in most cases it is determined individually for each patient, taking into account the severity of the pathology, age and other characteristics of the patient.

Analogues

Sometimes there are situations when it is not possible to buy Budesonide for inhalation in a pharmacy. Therefore, many patients have a question: is it possible to replace this drug with another, equivalent remedy?

Indeed, such inhalation drugs exist, and there are quite a lot of them. They are complete analogues of Budesonide, however, despite this, their replacement must be approved by the attending physician.

We present you with a list of similar drugs:

• Budekort
• Novopulmon
• Pulmax
• Tafen
• Pulmicort for inhalation

In some cases, for example, with individual hypersensitivity or in the presence of contraindications, the hormonal drug Budesonide for inhalation can be replaced by another non-hormonal agent with an anticholinergic effect. In such a situation, Berodual works great - it is a combination drug that combines two active ingredients with adrenergic and anticholinergic activity. Berodual is suitable for inhalation in chronic obstructions, allergic and endogenous bronchial asthma, tension asthma, and chronic obstructive bronchitis.

The drug Spiriva, which contains tiotropium bromide, has an anticholinergic property similar to Berodual. This drug can be used for inhalation to alleviate the condition of patients with chronic obstructive pulmonary disease. However, it should be noted that Spiriva is used only as a maintenance drug and is not suitable for eliminating acute asthma attacks and bronchospasm. The frequency of use of the drug is also limited - no more than once a day.

Taking into account the fact that in pediatric practice and during pregnancy the use of Budesonide for inhalation is limited, the doctor may prescribe the patient one of the drugs with anticholinergic activity.

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