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Highly differentiated adenocarcinoma

 
, medical expert
Last reviewed: 23.04.2024
 
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By the degree of formation of a specialized phenotype in cell division during morphogenesis, such tumors are carried on several types, one of which is a highly differentiated adenocarcinoma, marked by a high degree of differentiation and insignificant cell polymorphism.

That is, in this case the structure of the cell changes insignificantly, only the growth of the size of the cell nucleus is observed. The area of localization of this pathology is quite extensive.

Adenocarcinoma is a cancerous growth that is formed from the epithelium of glandular tissues due to the failure of their reproductive program.

trusted-source[1], [2], [3], [4], [5], [6], [7], [8],

Causes of highly differentiated adenocarcinoma

Scientists and physicians have long been trying to find the causes of highly differentiated adenocarcinoma with insignificant progress. From the moment when it will be possible, it can be safely said that a medicine capable to relieve a person of this problem will be found in speed, and while the medicine has learned to diagnose the disease, assuming the reasons for its occurrence.

  • Genetic heredity.
  • Frequent neuroses and stressful conditions.
  • Age. Older people are more likely.
  • Lack of balanced varied nutrition. Low in food plant foods. In food prevails fats, carbohydrates in the form of flour and sweet dishes. Cancer, in some cases, can provoke an unsuccessful diet.
  • Diabetes.
  • Professional activities related to work with harmful substances.
  • Medical preparations.
  • Highly differentiated adenocarcinoma of the rectum can be triggered by the occupation of anal sex.
  • High degree of obesity.
  • Viral infection of human papilloma.
  • Cause of cancer of the uterus is called a hormonal failure caused by an increased amount of estrogen in the blood (female sex hormone).
  • Various kinds of diseases of vital organs: ovaries, rectum and colon, prostate.

But this list can not be called final. It is difficult to voice and all the risk factors that are capable of provoking cancer tumors of one or another organ.

trusted-source[9], [10], [11], [12],

Symptoms of highly differentiated adenocarcinoma

It is necessary to clarify that initially malignant tumors of such differentiation do not manifest themselves in any way and the patient for a time does not even guess about its existence. Only in time the symptoms of a highly differentiated adenocarcinoma begin to appear. In this case, the symptomatology may vary slightly depending on the location of the tumor.

  • Appearance of aching pain in the area of neoplasm.
  • Rapid weight loss, loss of appetite.
  • In case of bowel cancer, there are:
    • Blood, mucous or purulent discharge in fecal masses.
    • Frequent alternation of diarrhea and constipation.
    • Inflammation of the intestine.
  • Symptomatic of uterine lesions can be:
    • Unpleasant smell.
    • Atypical discharge from the vagina during the intermenstrual period.
    • Drawing pain symptomatology, observed in the lower abdomen.
    • Abundant discharge during menstruation.
    • Pain caused by intercourse.

Highly differentiated adenocarcinoma of the large intestine

Cancer of the large intestine - this term, often, means several different forms of manifestation of a cancerous tumor, its histology and localization. This includes epithelial cancer neoplasms of the direct, colon blind and, in fact, the large intestine.

To date, this pathology ranks second in the world, especially in highly developed industrial countries, in terms of the incidence of diseases. In particular, the statistics given by the highly differentiated adenocarcinoma of the large intestine are quite deplorable: about 16,000 patients who have been diagnosed with colon cancer die annually only in England and Wales. The United States voices an even more horrifying figure: new cases of the disease from 14 to 150 thousand people, while the annual death rate from this disease exceeds the figure of 50 thousand people.

The first symptoms that should alert a person and encourage him to seek medical advice should be atypical discharges, observed together with the calves - these are blood veins (and even bleeding), mucous or purulent discharge.

By the color of the blood, the specialist is able to accurately assume even the localization of the cancer: the scarlet blood is inherent in the neoplasms of the rectum and the anal canal, for the colorectal cancer of the left part the darker blood color is more characteristic. Most often, blood, mucus and feces are mixed, ascertaining the greater reliability of the trait. For a right-sided lesion of the colon, hidden bleeding is inherent. The manifestation of it may be weakness, pale skin and obvious signs of anemia.

More often problems with defecation are characteristic for severe late forms of the disease and are more characteristic of malignant tumors of the rectum and left side of the colon. There are cases when cancer of the large intestine manifests itself immediately with acute intestinal obstruction. This situation requires immediate surgical resolution.

Highly differentiated cecal adenocarcinoma

This is one of the most common cancer pathologies of the intestine. The maximum number of diseases falls on patients aged 50 to 60 years, but young people are not insured from it.

The impetus to the development of cancer can be:

  • Inoculated or adenomatous polyps.
  • Proctosigmoiditis - inflammatory processes occurring in the lower part of the sigmoid (colon) and rectum.
  • Proctitis of a chronic nature.

It is almost impossible to predict or predict this pathology. The main task of doctors and the patient is not to miss symptoms and take adequate measures in time.

Highly differentiated sigmoid colon adenocarcinoma

The scourge of modern society has become malignant neoplasms, affecting the mucous membrane of the large intestine and rectum. In elderly people, this pathology ranks second in the intensity of the disease. The sigmoid colon is one of the areas of the intestine.

This is the degeneration of mucosal cells into cancerous formations, the localization of which "selects" the sigmoid region of the intestine. Pathology does not reveal any symptoms in the early stages of development, it can be diagnosed only through regular screening. For the most part, people of advanced age who are over 50 are at risk.

Highly differentiated rectum adenocarcinoma

The share of malignant epithelial tumors of the rectum accounts for about 4-6% of the cases of this "plague of the 20th century". The peak number of diseases is observed in highly developed countries, such as: the USA, Canada, the countries of Western Europe, Russia. A much smaller percentage marked the countries of Africa and Asia.

As a rule, the highly differentiated adenocarcinoma of the rectum begins to manifest itself with this symptomatology:

  • The patient does not leave the desire to go to the toilet, he almost all the time feels a false urge to empty the intestines.
  • There is weakness.
  • Less often comes the feeling of hunger.
  • Decreased ability to work.
  • There is a significant loss of body weight.
  • An earthy complexion.
  • Explicit anemia.
  • There is swelling and rumbling in the abdomen.
  • Strengthening of peristalsis.
  • Constipation.
  • With the growth of the tumor, there are anal bleedings, which eventually increase, periodically exiting the blood clots, but diffuse bleeding does not happen.
  • At a later stage of the disease, hepatomegaly (a pathological increase in liver size) and ascites (accumulation of free fluid in the peritoneal cavity (peritoneal dropsy)) is observed.

Symptoms of malignant neoplasms are largely determined by the size of the tumor, the level of invasion, the site of localization. As you grow, the symptoms become more pronounced and diverse.

Physicians distinguish three stages of highly differentiated rectal adenocarcinoma:

  • I stage: neoplasm up to 2 cm in size, the site of localization - the mucous and submucous layer of the rectum. Metastasis is not observed.
  • II stage: neoplasm of up to 5 cm, covers less than half of the gut lumen, localization - does not extend to nearby tissues.
    • Stage IIa - without metastasis.
    • stage IIb - regional metastasis is observed.
  • III stage: the size of the cancerous area is more than 5 cm, the area of overlap of the lumen of the rectum is more than 50%, a more profound growth of metastases is observed.

Highly differentiated gastric adenocarcinoma

Malignant neoplasm of glandular epithelium of the stomach, that is, the development of oncology in the glandular layer of the stomach is one of the most common oncological diseases in the world today. Cancer of the stomach occupies the fourth place among other cancers. Develop a malignant tumor of the stomach can in any of its departments, but most often it is found in the antrum and pyloric sections, that is, "at the outlet" of the stomach.

An impetus to the progression of such a disease as a highly differentiated adenocarcinoma of the stomach can be the Helicobacter pylori virus, chronic gastric ulcer diseases, subtotal gastrectomy, atrophic gastritis and multiple other diseases of the gastrointestinal tract.

With this pathology, a mutation of the genetic apparatus of the affected cell is observed. Diagnosing this disease is rather difficult because of the fact that for the time being the aberrant cell is practically not different from normal. If the doctor - the oncologist ascertained stomach cancer, in 90% of cases - this is a serious stage of the disease, when it is difficult to help the patient. The likelihood of a lethal outcome is very high.

In addition to the above, the risk of getting a high-grade gastric adenocarcinoma increases if the patient has a history of:

  • Adenomatous polyps.
  • Problems with the integrity of the epithelium of the gastric mucosa.
  • Disease Menetries.
  • With improper nutrition: the abuse of smoked, salted food, canned food, products with preservatives, modified food.
  • Genetic heredity.
  • Overweight.
  • Accommodation or work in the zone of high radiation.

In addition to "traditional symptoms," a malignant neoplasm in the stomach provokes:

  • Change in taste preferences.
  • Feeling of heaviness in the stomach after eating.
  • Jaundice is non-infectious.
  • Change in calorific value.
  • There is a loss of body weight, with the stomach increasing in volume.
  • The appearance of pain and discomfort in the stomach.

Chronic pancreatitis, smoking can provoke a highly differentiated pancreatic adenocarcinoma.

The malignant neoplasm of the stomach has many varieties, depending on the form of the tumor itself, the way it develops. Important is the histological characteristics of the tumor, as the level of differentiation of cells. If we are talking about highly differentiated adenocarcinoma, the pathological cells do not have a strong difference from the cells of the tissue that formed the tumor. Such a neoplasm develops relatively non-aggressively and has the most favorable prognosis against a background of tumors with a lower level of cell differentiation. But nevertheless, its other characteristics are also important for the adequate treatment of a highly differentiated gastric adenocarcinoma.

One of the most common and used in the world is the Bormann classification, which distinguishes four main types of malignant neoplasm of glandular epithelium of the stomach:

  • Polypoid

This type of cancer has quite clear boundaries, there are no ulcers. It occurs quite rarely - in about 6% of cases of a malignant neoplasm of the stomach.

  • Non-infiltrating (saucer-like)

Such a cancer resembles a kind of ulcer, has more extended borders. If it occurs, a thorough histological examination is required to clarify the diagnosis.

  • Infiltrative

Such a cancer has the property to germinate into the deeper layers of the walls of the stomach, has no clear boundaries, also resembles a stomach ulcer. This type of cancer is prone to active metastasis.

  • Diffuse infiltrative (solid)

In this case, the cancer grows into the deep layers of the stomach, the motor activity of the stomach is significantly reduced. If the cancer has developed extensively, then the stomach itself practically loses its functionality and greatly narrows. In the lesion site, ulcers, erosion and hemorrhage can occur. In such a subset of cancer, oncological and infectious processes are often associated.

Among the listed types of cancer, the latter two most unfavorable predictions. They most affect the stomach and are difficult to diagnose in the early stages. Similarly, the last two types of malignant neoplasm of the glandular epithelium of the stomach have a higher propensity to metastasize, which significantly complicates the treatment of the patient and worsens the prognosis.

Highly differentiated adenocarcinoma of the prostate

Prostate cancer - this disease affects mainly elderly men, and is characterized by a mutation of cells of glandular epithelium of alveolar-tubular structures. The primary location of the pathology is the peripheral area of the prostate gland. One of the modifications of such malignant neoplasms is a highly differentiated adenocarcinoma of the prostate gland.

Malignant neoplasm of glandular epithelium of the prostate gland is a malignant tumor formed from glandular tissues of the prostate gland.

To date, adenocarcinoma of the prostate gland occupies the first place among malignant formations in men. The highly differentiated adenocarcinoma has the least aggressiveness, but nevertheless, the danger of this disease is very high.

Most often this disease occurs in elderly men, but over the years, an increasingly young man is faced with this problem. And on average, prostate cancer reduces the life expectancy of patients by 10 years.

Symptomatic of this lesion, as in the case with other types of cancer, begins to appear only in the late stages of the disease, when obstruction begins to seize and ureters. Therefore at earlier stages this pathology can be diagnosed only when examined by a doctor. You can presume the diagnosis by taking a digital rectal examination of the proctologist. Further, the PSA value is monitored and a biopsy is performed.

The causes of this malfunction in the body are:

  • Age of the man.
  • Equilibrium balance of nutrients.
  • The XMRV virus.
  • Poisoning the body of a man with cadmium, or prolonged exposure to a given substance.

The main symptomatology:

  • Manifestation of painful sensations in the region of the hip joints. There is a feeling that the spine and ribs are hurting.
  • Increases the feeling of weakness, apathy.
  • An increase in the frequency and duration of urination is fixed, the procedure becomes painful.
  • There may be incontinence.

All this symptomatology is inherent in prostate adenoma, which confuses an inexperienced doctor in setting the right diagnosis. If adequate treatment is carried out, when the pathology has not yet developed, the prognosis of patients diagnosed with prostate cancer is favorable in most cases.

Highly differentiated adenocarcinoma of the prostate gland is a malignant neoplasm, which reduces the life of the representatives of the stronger sex for at least 5-10 years. Difficulty diagnosing in the early stages significantly increases lethality, second only to lung cancer.

The danger of the disease also lies in the fact that it, like many other oncological processes, does not have precisely expressed symptoms. With the development of this disease, symptoms such as frequent urge to urinate may be observed. At the same time there is a feeling of incomplete emptying of the bladder, the jet is intermittent, there may be difficulties and painful sensations when urinating.

Similar symptoms can occur with a number of diseases of the prostate and the organs of urination, so when they appear, it is necessary in any case to see a doctor to exclude prostate cancer.

A highly differentiated adenocracinoma does not practically metastasize. But this process also has its own peculiarities in the case of adenocorticoma of the prostate gland. The prostate gland itself has a capsule. When the tumor grows into adjacent tissues, the capsule limits growth. Thus, metastases most often penetrate into the bottom of the bladder and seminal vesicles.

In addition, the tumor can spread through the lymphatic and blood channels. But in the case of a highly differentiated adenocarcinoma, this probability is very small and is about 10%.

Highly differentiated adenocarcinoma of the lung

A highly differentiated adenocarcinoma is a type of tumor that can develop from the glandular tissue in any organ where it is present, in this case it is lung tissue. By its structure, its cells differ little from the cells of the organ in which it was formed.

Quite often the highly differentiated adenocarcinoma of the lung is manifested by the production of mucous secretions. In this case, the structure of mucus is represented by large cells with a large nucleus located in the basal region. Together, cancer cells and mucous masses are observed in the tissue lumens (there are tumors in which mucous formations are absent).

Risk factors include:

  • Long-term smoking.
  • Second hand smoke. A person does not smoke himself, but for a long time he is in close contact with smokers. At the same time the risk of cancerous growths in a non-smoker increases by 30%.
  • Professional activity, production costs of which are inhalation of carcinogens.
  • Lack of fruit and vegetables.
  • Living or working in an area with increased radiation.
  • Older, chronic lung diseases:
    • Tuberculosis.
    • Bronchitis.
    • Pneumonia.
    • Pneumonia.

The highly differentiated adenocarcinoma of the lung progresses slowly, but already in the early stages of the disease it is intensively carried by the blood vessels, metastasis is observed later. With the natural course of the disease, without passing the treatment course, the final one is a fatal outcome.

Lung cancer has a number of distinctive features. In particular, this type of cancer occurs in men more often than in women, can actively metastasize, with it is characterized by active mucus secretion. Especially dangerous are metastases. In this case, they can spread not just into neighboring organs, but enter the brain, liver, bones, adrenals. The malignant neoplasm of the glandular epithelium of the lung is also growing quite rapidly (the size of the tumor can double in half a year). All possible lung cancers are conventionally divided into small-cell and non-small-celled. Adenocarcinoma is the most common type of cancer among non-small cell lung cancers.

Highly differentiated adenocarcinomas are divided into acinar and papillary forms. In the first, glandular structures with large cells predominate, and secondly, papillary structures. Both varieties are prone to mucus, in the cells of the tumor are large vacuoles with mucus. The cancer develops on the peripheral parts of the lung, and it is quite rare to find tumors of this kind on the large bronchi.

Also, to highly differentiated adenocarcinomas, bronchialoalveolar cancer is perirolically classified, which is dangerous because it develops asymptomatically and is found most often by chance.

In the rest, the main symptom is abundant sputum. The tumor is detected by microscopic examination of mucus, as well as by X-ray examination.

Highly differentiated mammary adenocarcinoma

The topic of breast cancer today is on everyone's lips. The urgency of this problem throughout the world is not in doubt. To date, every thirteenth woman at the age of 20 is facing this problem.

One type of breast cancer is a highly differentiated adenocarcinoma. This development of the tumor from the glandular part of the cells of the breast. Such a tumor by the structure and functions of cells does not differ significantly from the tissue that formed it, and even is capable of retaining producing functions.

This pathology is a cancerous growth consisting of mutated cells of glandular epithelium, which have a corresponding localization. In the event that the cellular structure does not differ greatly from the norm, the structure of the neoplasm visually resembles the natural outline of the gland and does not manifest itself pathologically before transitioning to later, neglected forms, a highly differentiated adenocarcinoma of the mammary gland is noted. This pathology almost completely supports the functioning of the substituted glands.

In addition to genetic predisposition, hormonal failure and weighed heredity, the risk of developing a highly differentiated adenocarcinoma can be encouraged:

  • Frequent injuries of the chest.
  • Mastopathy of fibrous or cystic nature.
  • Women who first gave birth after 30 years.
  • Sexual maturation and girls began much earlier than normal.
  • Infertility.
  • The period of menopause.
  • A tumor of a benign character can be regenerated into a cancerous growth.
  • In the treatment of other diseases, significant doses of hormonal drugs were taken.
  • Congenital anomalies in the structure of the breast of a woman.
  • Smoking and alcoholism.
  • Incorrect food.

Symptoms of highly differentiated mammary adenocarcinoma:

  • At palpation elastic seals of a spherical outline are defined.
  • The hollow nipple.
  • The shape of the mammary gland underwent changes.
  • Growth in the size of the axillary, subclavian and supraclavicular lymph nodes.
  • There are discharge from the nipple.
  • Change the color of the skin in the chest.
  • The mammary glands of the right and left breast are located at different levels.
  • Appear edema.
  • In later terms, pain symptoms appear.

The highly differentiated adenocarcinoma itself can differ in a number of characters. Depending on the location of the tumor, the lobar and lobular cancers are isolated. To choose the tactics of treatment, it is very important to correctly determine the form of cancer. Breast cancer can be papillary (the rarest and most dangerous form of the disease), inflammatory (it resembles mastitis in its manifestations), medullary (a large tumor, but does not grow into neighboring tissues), and also give rise to Paget's cancer (a disorder caused by a halo and a nipple tumor ) and protocol infiltrative (the most common form of the disease).

In addition, there are several stages of the development of the disease - from zero to the fourth. Stage 0 describes a tumor that does not go beyond its origins, stage 1 tumor of small size, but invasively and affects adjacent tissues, stage 2 affects axillary lymph nodes next to the tumor, stage 3 is divided into two subgroups, in case of 3A tumor is more two centimeters, while the lymph nodes are soldered, at stage 3B, the tumor is already germinating into the adjacent tissues and the skin of the breast, at 4 stages the tumor grows beyond the chest and can affect other organs such as the liver, bones, lungs and the brain.

Early diagnosis and adequate treatment can significantly improve the quality of life for a woman and prolong life itself.

Diagnosis of highly differentiated adenocarcinoma

Any diagnosis of a cancerous nature is a series of standard techniques. Naturally, some differences still exist.

Diagnosis of highly differentiated adenocarcinoma includes:

  • Analysis of patient complaints.
  • Study of his anamnesis.
  • Inspection specialist.
  • Clinical studies: an extensive blood test, urine and fecal matter analysis for the presence of hidden blood, other studies necessary to recreate a complete clinical picture.
  • Hysteroscopy with biopsy. Conducting a histological examination of curettage materials (cytological smear) (with uterine cancer) or tissues of the diseased organ.
  • Ultrasound examination of the "dubious" region.
  • Finger examination of the rectum (if there is a suspicion of a cancerous lesion in this area).
  • Colonoscopy. A doctor-endoscopist has the opportunity to view the condition of the mucosa of the inner layer of the large intestine. A special probe helps him to score.
  • Irrigoscopy (if the colonoscopy did not give a full answer to all questions) - X-ray examination of the large intestine with retrograde intake of radiopaque means.
  • Endorectal ultrasound.
  • If necessary, radiography is prescribed.

trusted-source[13], [14], [15],

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Treatment of highly differentiated adenocarcinoma

Cancer tumors of different localization, provides its own peculiarities of process cupping. But in any case, a comprehensive treatment of highly differentiated adenocarcinoma is carried out. Practice is the application of several methods simultaneously. The intensity of treatment is adjusted depending on the site of the lesion, the stage of development of the tumor and the presence or absence of metastases.

To establish a pathology and to conduct the necessary treatment is necessary in a short time, since in the case of a cancerous tumor, even a slight delay can cost the patient a life.

It is almost impossible to avoid surgical intervention, but modern methods allow, for example, in the case of highly differentiated rectal adenocarcinoma, to perform surgical treatment without opening the patient. But the result of therapy will be favorable only if healthy tissues that are close to the pathology are protected from damage. To solve this problem, along with surgical intervention, radiotherapy is used. Apply and radioactive cesium. Its effect makes it possible to reduce the volume of neoplasm.

To "destroy" the mutated cells, oncologists actively scrub the chemotherapy. It is often used drugs such as Cisplatin (Platinol), Carboplatin (Paraplatin), Docetaxel (strongly attributed to the diagnosis of lung tumors), Adriamycin, Bleomycin, Vinblastine, Fluorocil and Epirubicin (for malignant gastric and intestinal pathology).

Cisplatin (Platinol). The drug is used as a dropper or injection, in a vein. The dosage is set individually at a rate of 30 mg per m 2 (the patient's body surface area). The medication is administered once every seven days:

  • with a single application, every three to five weeks, the amount is calculated as 60-150 mg per m 2.
  • with a daily application, a dosage of 20 mg / m 2 is used. Entering is carried out for five days. A repeat course in four weeks;
  • an estimated amount of 50 mg per m 2 of the body area of the patient is introduced every first and eighth day of a four-week block.

In combination with radiation exposure, the drug is injected into the vein daily, at a dose of up to 100 mg.

Depending on the location of the tumor, the oncologist can prescribe the drug intraperitoneally and intrapleusively. The amount of delivered medicinal product is established by the doctor individually within the limits of 40-100 mg. If the drug is delivered directly to the neoplasm - Cisplatin is not subjected to strong breeding.

The most common side effects are:

  • Weakening of hair bulbs and their loss.
  • Neuropathy of peripheral nerves.
  • Education in the mouth of sores.
  • Failure in the work of the digestive organs.
  • Nausea, resulting in vomiting.
  • Depressive state.
  • Apathy.
  • Loss of appetite.
  • Decreased vitality.
  • Defect of taste.
  • Anemia.
  • Reducing the number of platelets in the blood.
  • Blocking of immunity.
  • There is a deviation from the natural color, the structure of the skin and nails.

Docetaxel. The medicine is attributed capillary, intravenously. Enter slowly, for an hour. A single dose is 75-100 mg / m2. A dropper is put once every three weeks.

All drugs used in chemotherapy are quite aggressive and their use does not go in vain for the organism, which, in response to aggression, is manifested by side effects. To partially or completely remove them, the oncologist has to prescribe additional medications to the patient, which are designed to ease these consequences.

Fluorocyl. The drug is often used in treatment schedules. It is injected into the vein. A doctor - an oncologist appoints him at a critical value of leukocytes. Fluorocil is a supportive agent. The daily dose of the drug is 1 g per 1 m2 of body area. Duration of reception - from 100 to 120 hours.

There is another reception protocol: 600 mg / m2. A dropper is placed every first and eighth day of the month. If the drug is taken with calcium, the dosage is reduced to 500 mg per m2. For three to five days, the drug is given daily. Then take a break in four weeks.

The course of treatment and rehabilitation time often stretches for half a year, or even more.

More information of the treatment

Prevention of highly differentiated adenocarcinoma

Specific preventive measures that allow to guarantee yourself and your loved ones from malignant neoplasms of different localization do not exist.

Prevention of highly differentiated adenocarcinoma, recommended by oncologists, is, first of all, taking steps to reduce the risk of developing the disease.

  • Control your weight. Excessive weight and leanness increase the risk of pathology.
  • Proper nutrition.
  • Active lifestyle.
  • Moderate physical activity.
  • Scheduled inspections of specialists.
  • Adequate treatment of chronic diseases.
  • Strike out of your life smoking, drugs and alcohol.
  • Walking in the air.
  • Learn to avoid stressful situations.
  • Harmonious combination of load and rest.
  • Minimize contact with harmful substances.

Prognosis of highly differentiated adenocarcinoma

In medicine, there is a term - five-year survival. The probability that the patient will be able to cross this Rubicon is affected by several factors: the size of the tumor, the depth of its penetration into the affected organ and the presence of metastases.

The larger the tumor size and the deeper it penetrated into the body tissues, the higher the prognosis of the highly differentiated adenocarcinoma is less optimistic. Does not give optimism and the presence of metastasis. But the typical affiliation of a cancerous tumor to a highly differentiated adenocarcinoma is encouraging, since it lends itself to more effective treatment (unlike a moderate or a low-grade one).

Especially favorable is the prognosis of highly differentiated adenocarcinoma in diagnosing pathology at an early stage of the lesion. Therefore, timely diagnosis and mobile adequate treatment are important. For example, a "five-year survival" in uterine cancer yields such percentages:

  • the course of treatment for the diagnosis of stage I - 86-98%,
  • treatment at the establishment of the II stage - 70-71%,
  • "Five-year survival" in the case of diagnosis of stage III - 32.1%,
  • at the IV stage - 5,3%.

Prognosis for highly differentiated colon adenocarcinoma

Due to the fact that highly differentiated cancer is amenable to effective treatment, the prognosis is more favorable than in case of moderate or low-grade cancer. But the result of treatment largely depends on the stage of the tumor process. If it was diagnosed early in life, the survival prognosis is 90%. But the more the process progresses, the more favorable the forecast is.

If the lymphatic system is already involved in the process, the percentage drops to 50. No more than 20% of the survival is caused by a tumor located on the right side of the colon.

Statistics show that the average time of occurrence of relapses is from one to one and a half years.

Highly differentiated adenocarcinoma is an insidious and dangerous disease and on how much you are attentive to your body, how much you will learn to "read" its signals about help, your life depends to a large extent. Therefore, at the slightest discomfort it is necessary to address for consultation to the doctor. It is better to be safe than to miss the disease.

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