Diseases of the liver and biliary tract

Chronic hepatitis C: treatment

Chronic hepatitis C treatment involves a complex. The therapy of this disease includes etiological, pathogenetic and symptomatic treatment.

Chronic hepatitis C: diagnosis

Diagnosis of chronic hepatitis C is based on laboratory tests, instrumental methods and differential diagnosis.

Chronic hepatitis C: symptoms

Chronic hepatitis C symptoms are lethargic. These signs last for many years. Acute attack usually remains unrecognized and proceeds without clinical symptoms, according to which it would be possible to predict chronicization. Nevertheless, 80% of patients develop chronic hepatitis and 20% have liver cirrhosis.

Chronic hepatitis C: causes

The cause of chronic hepatitis C is the hepatitis C virus, which was identified in 1989. Houghton et al. The hepatitis C virus often leads to the development of chronic hepatitis, which can progress to cirrhosis and hepatocellular carcinoma. The transition of acute viral hepatitis C into chronic is observed in 50-80%.

Chronic hepatitis C

Chronic hepatitis C in most cases is a consequence of acute hepatitis. In comparison with other hepatitis viruses, the hepatitis C virus has rather strong chronogenic properties.

Chronic hepatitis B: treatment

Treatment of chronic viral hepatitis B is aimed at suppressing the contagiousness, destroying the virus, preventing the development of liver cirrhosis and, possibly, hepatocellular carcinoma. No method of treatment does not relieve the patient of the virus, nevertheless successful antiviral therapy allows to reduce the severity of the process and the necrosis of hepatocytes caused by it.

Chronic hepatitis B: diagnosis

To suspect the presence of hepatitis B virus in hepatocytes can be due to the presence of matte-vitreous hepatocytes in the study of drugs stained with hematoxylin and eosin or by the Van Gyzon method.

Chronic hepatitis B: symptoms

Chronic hepatitis B can be diagnosed in donors at the time of blood donation or routine blood screening based on the detection of HBsAg and a moderate increase in serum transaminase activity.

Chronic hepatitis B: stages of HBV infection

In the life of the hepatitis B virus, two periods are distinguished: the period of virus replication, accompanied by the activity of the inflammatory process in the liver, and the period of virus integration, in which the activity of inflammation subsides occurs the phase of remission of the disease (inactive phase). The marker of the replication phase is HBeAg.

Chronic hepatitis B

Chronic hepatitis is not always preceded by an identifiable acute form of hepatitis B. However, sometimes immediately after an acute episode, chronicization occurs. In other cases, despite a sudden onset, similar to an acute disease, chronic hepatitis already occurs.

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