Serological tests

Antibodies to cytomegalovirus class IgM and IgG in blood

IgM antibodies to cytomegalovirus appear within 1-2 weeks after the onset of the disease and indicate a fresh infection or reactivation of a latent and persistent infection. IgG antibodies to cytomegalovirus appear 2-4 weeks after infection and persist for up to 10 years in those who have recovered.

Infectious mononucleosis: antibodies to Epstein-Barr virus in blood

Epstein-Barr virus is a herpes virus that has tropism for B-lymphocytes and persists in host cells for a long time as a latent infection. It is widespread throughout the world.

Chickenpox: IgM antibodies to varicella zoster virus in blood

When using the RSC, antibodies to the varicella-zoster virus in the blood serum are detected on the 7th-10th day after the appearance of the rash, their quantity reaches a peak by the 2nd-3rd week. A 4-fold increase in the antibody titer (sensitivity 50%) indicates an acute infection.

Herpes test

The ELISA method is used to determine IgM and IgG antibodies to herpes simplex virus-1 and 2. Optimal testing includes determination of antibodies of different classes separately to herpes simplex virus-1 and 2.

Hepatitis G test: IgG antibodies to HGV in blood

Viral hepatitis G is an infectious disease with a parenteral mechanism of infection (mainly through blood transfusions). The viral hepatitis G virus (HGV) belongs to the Flaviviridae family.

Hepatitis E test: IgG and IgM antibodies to HEV in blood

For specific diagnostics of viral hepatitis E, the ELISA method is used, based on the detection of IgM antibodies (anti-HEV IgM), which appear in the blood 3-4 weeks after infection (10-12 days from the onset of clinical manifestations of the disease). Detection of anti-HEV IgM in the blood serves as laboratory confirmation of the diagnosis.

Hepatitis D test: IgM antibodies to HDV in blood

Viral hepatitis D is a viral infection that, due to the biological characteristics of the virus (HDV), occurs exclusively in the form of co- or superinfection against the background of viral hepatitis B, characterized by a severe course, often with an unfavorable outcome.

Hepatitis C test: serum HCV antibodies

The HCV genome is represented by a single-stranded positively charged RNA, which codes for 3 structural (nucleocapsid protein core and nucleoproteins of the envelope E1-E2) and 5 structural (NS1, NS2, NS3, NS4, NS5) proteins. ATs are synthesized for each of these proteins, which are found in the blood of patients with viral hepatitis C.

Hepatitis B test: HBSAg in blood

Detection of hepatitis B surface antigen (HBsAg) in serum confirms acute or chronic HBV infection.

Hepatitis A test: serum IgM antibodies to HAV

Reliable confirmation of the diagnosis of viral hepatitis A is carried out by serological methods - detection of an increase in the level of specific antibodies (anti-HAV) belonging to IgM (anti-HAV IgM).

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