Berylliosis of the skin
Last reviewed: 23.04.2024
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Berylliosis is a systemic occupational disease with primary respiratory damage, which is based on the formation of typical immune granulomas from the introduction of metals. Beryllium granulomas in the skin develop as a result of ingress of beryllium through damaged skin, less often - hematogenous. Clinically, the lesions have the appearance of small or large-scale, cyanotic or yellowish-red formations, similar to those in sarcoidosis. There may be ulceration. Skin tests with beryllium are usually sharply positive.
Pathomorphologists of berylliosis
Skin granulomas in systemic berylliosis are not distinguishable from granulomas in sarcoidosis, since they are almost not subjected to necrosis. Particles of beryllium, as a rule, are not visible in histological sections, but they are detected by spectrography.
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