Wagner's disease: causes, symptoms, diagnosis, treatment
Last reviewed: 23.04.2024
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Wagner's disease also refers to vitreoretinal dystrophies with an autosomal dominant type of inheritance. The gene responsible for the development of Wagner's disease is localized on the long arm of the 5th chromosome.
Symptoms of Wagner's disease
The main clinical symptoms of Wagner's disease are the presence of myopia, often high degree, and preretinal membranes with an "optically empty" vitreous body in combination with retinoschisis, retinal dystrophy and pigment epithelium. Already at the age of 10-20 years, opacities of the lens are detected, which rapidly progress; Secondary glaucoma and retinal detachment are often observed.
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Diagnosis of Wagner's disease
The diagnosis is based on family history, the results of biomicroscopic and ophthalmoscopy, perimetry, electroretinography and fluorescent angiography. With perimetry, a concentric narrowing of the field of vision is detected, more rarely a ring-shaped cattle. ERG abnormally subnormal.
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