Treatment of human papillomavirus with drugs: ointments, pills, injections, suppositories

The human papilloma virus, like any other infectious agent, requires complex therapy. Treatment depends on the type of HPV, its oncogenicity and a number of other factors. The main direction in treatment is the removal of growths in combination with a course of antiviral therapy.

A doctor is responsible for drawing up a treatment plan for HPV. The doctor takes into account the results of the diagnostics and such factors as:

• Virus concentration.
• Risk of malignancy.
• Severity of external symptoms.
• The degree of damage to the epithelium.

The presence of concomitant pathologies is also taken into account, since papillomatosis very often occurs together with other diseases. If after a comprehensive examination only HPV is detected, then the treatment consists of:

• Taking antiviral drugs.
• Strengthening the immune system's defenses with immunomodulators.
• Vitaminization of the body.
• Removal of skin defects.
• Folk remedies.

If a woman is diagnosed with cervical dysplasia against the background of a viral infection, the course of treatment includes taking cytostatics or other medications to suppress the growth of existing and the appearance of new atypical cells. If HPV is diagnosed during pregnancy, treatment is carried out in the last trimester, when all the organs of the fetus are formed and medications will not cause congenital pathologies.

Can HPV be cured?

Many people, faced with such a disease as the human papilloma virus, make erroneous conclusions about the outcome of this problem. Some believe that the virus can be completely eliminated, while others, on the contrary, are sure that the infection always leads to cancer and death.

When infected with HPV, the concept of "curing the virus" is not used. Today, there are simply no drugs that would completely kill and remove infectious strains from the body. But there are medications that suppress the activity of pathogenic microorganisms and help the body recover from diseases caused by the virus.

It is also necessary to take into account the fact that HPV is not always dangerous for the body. Only genotypes with a high oncogenic risk pose a serious threat of developing cancer. In any case, timely medical attention and comprehensive diagnostics will help prevent possible complications of Human papillomavirus and suppress its activity.

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Medicines

Drug therapy is a mandatory component of papillomavirus treatment. The medication is selected by the attending physician, individually for each patient. When choosing a medication, the strain of the virus, its quantitative indicators, the presence of concomitant diseases and the degree of oncogenicity of HPV are taken into account. In almost all cases, therapy is aimed at eliminating the symptoms of the infection, and not removing it from the body.

There are many medications of different forms and effectiveness that can be used for HPV. But most often, patients use the following drugs:

• Ferrovir

A biologically active agent with an immunomodulatory and anti-inflammatory effect. The drug is an extract from salmon and sturgeon milk. The active substance activates immune responses that protect the body from fungi, viruses and bacteria. It has a broad antiviral spectrum. Each bottle of the drug contains 75 mg of sodium deoxyribonucleate and 0.24 mg of iron chloride hexahydrate.

• Indications for use: complex treatment of viral and infectious diseases. Suitable for the treatment of HIV, hepatitis C, herpes infections, HPV, tick-borne encephalitis.
• Method of administration: the medicine is used for intramuscular injection. The dosage and course of treatment are determined by the attending physician, for each patient individually.
• Side effects: short-term increase in body temperature and blood flow to the skin, pain at the injection site. Overdose has similar but more pronounced symptoms.
• Contraindications: hypersensitivity to the components of the drug, pediatric practice, pregnancy and lactation.

Ferrovir is available in vials containing 5 ml of solution for intramuscular injections each.

• Wobenzym

A combination of active enzymes of animal and plant origin. Has anti-inflammatory, immunomodulatory, anti-edematous and fibrinolytic effects. 1 capsule contains 250 mg of proteolytic enzymes from pineapple and papaya, as well as 100 mg of pancreatitis, 60 mg of papiin, 45 mg of bromelain and other substances.

• Indications for use: rheumatoid arthritis, thrombophlebitis, inflammation of the genitourinary tract, chronic gynecological infections, inflammation of the upper and lower respiratory tract. Prevention of viral and infectious lesions of the body.
• Directions for use: 5-10 tablets 3 times a day 30 minutes before meals. The course of treatment is determined by the attending physician.
• Side effects: skin rashes, bowel disturbances.
• Contraindications: hemophilia and thrombocytopenia, pregnancy and lactation, early childhood patients.

Wobenzym is available as enteric-coated tablets in packs of 40, 200 and 800 pieces.

• Superchistotel

A medicinal product for local treatment of papillomatous rashes. The mechanism of action of the drug is a chemical burn of the affected tissues by the active components of the drug. Allows you to remove skin growths in a few days. It is used to remove warts, papillomas, calluses and as a means for skin care with excessive keratinization.

Superchistotel contains the following components: potassium hydroxide, sodium hydroxide and distilled water. The drug is prohibited for use on the skin in the facial area. Side effects are manifested in the form of skin allergic rashes.

• Podophyllin

A medicinal product with cytotoxic activity. Suppresses proliferative processes in the body, stops the growth of papillomas, condylomas and other skin defects. The preparation contains a complex of natural compounds from the rhizomes of Podophyllum peltate.

It is used for papillomatosis of the larynx and bladder in children and adults. Before taking the medicine, surgical removal of skin deformities is performed. The affected areas are treated with a solution of this drug once every two days.

When the medicine is introduced into the bladder, severe pain in the lower abdomen, burning in the bladder area and urination disorders are possible. During the treatment of laryngeal papillomatosis, attacks of nausea and vomiting, various gastrointestinal disorders often occur.

• Salicylic acid

Antiseptic, keratolytic and irritant. Used for external treatment of skin defects. Very often included in ointments, pastes and powders for epidermis care.

To treat papillomas or warts, salicylic acid in the form of an ointment or paste should be applied to the affected tissues. The treatment lasts until the neoplasms disappear completely. In some cases, allergic reactions occur at the sites of application, and a slight burning sensation is also possible.

• Genferon

Suppositories with active components: Alpha-2 interferon recombinant human, anesthesin and taurine. The drug stimulates local and systemic immunity, has an antiviral and antibacterial effect. Stops inflammatory processes, destroys viruses, fungi and other pathogenic microorganisms.

• Indications for use: human papillomavirus, genital herpes, urogenital chlamydia, chronic vaginal candidiasis, mycoplasmosis, trichomoniasis. Used for diseases of the cervix, urethritis, balanitis and prostatitis.
• Method of application: women are prescribed 1 vaginal suppository 2 times a day for 7-10 days. Men are treated rectally, 1 suppository 2 times a day, the duration of therapy is 10 days.
• Side effects: temporary allergic reactions. In rare cases, there is an increase in body temperature, headaches, loss of appetite.
• Contraindications: intolerance to the components of the drug, allergic or autoimmune diseases in the acute phase. During pregnancy, the drug can be used no earlier than 12 weeks and only on doctor's prescription.

Genferon is available in the form of suppositories of 250 thousand IU, 500 thousand IU and 1 million IU. One package may contain 5 or 10 suppositories.

If the medicine for Human papillomavirus is chosen correctly, the therapeutic effect will be fast and strong. In addition, timely drug therapy significantly reduces the risk of relapses of the disease.

Tablets for human papillomavirus

The most common form of drugs used to treat various diseases is tablets. For the human papilloma virus, antiviral and immunostimulant drugs for oral use are prescribed.

The following tablets are used for the treatment of HPV:

• Alpizarin

Antiviral agent with active components tetrahydroxyglucopyranosylxanthene and mangiferin. Stops the reproduction of virus cells, increases the productivity of all immune system structures. Has an immunostimulating effect by increasing the production of gamma interferon.

• Indications for use: herpetic and papillomatous lesions of the body, cytomegalovirus infection, viral pathologies in dentistry, chickenpox, Kaposi's eczema herpetiformis, lichen planus and other viral dermatoses.
• Directions for use: Take 1-2 tablets 3-4 times a day. Duration of treatment is 10 days or more.
• Side effects: nausea, vomiting, headaches, bowel disturbances, skin allergic reactions, angioedema.
• Contraindications: hypersensitivity to the components of the drug, first trimester of pregnancy, patients under 36 months, impaired absorption of simple sugars, lactation.

The medicine is available in tablet form with 10, 20, 30 tablets per package. Alpizarin is also available in the form of an ointment.

• Lycopid

An immunomodulatory agent with the active component glucosaminylmuramyl dipeptide. Its mechanism of action is based on interaction with specific centers in the endoplasm of T-lymphocytes and phagocytes. Stimulates the phagocytic activity of neutrophils and macrophages. Enhances bactericidal and cytotoxic activity.

• Indications for use: complex treatment of diseases with secondary immunodeficiencies. Prescribed for acute and chronic purulent-inflammatory lesions of soft tissues and skin, after surgical interventions. Used for papillomatous infections, herpes, viral forms of hepatitis B and C, pulmonary tuberculosis, psoriasis, infectious lesions of the upper and lower respiratory tract.
• Method of administration: for HPV, 2 mg is prescribed 1-2 times a day; in severe cases of infection, the dosage is increased to 10 mg 1-2 times a day. The course of treatment is 6 days.
• Side effects: hyperthermia, headaches, nausea.
• Contraindications: intolerance to the components of the drug, diseases with hyperthermia, fever, pregnancy and lactation, patients under 3 years of age.

Likopid is available in the form of tablets, 10 pieces per blister, 2 blisters per package.

• Arbidol

An antiviral agent that suppresses the activity of influenza viruses A and B and other infectious agents. The drug is taken 2 tablets 3-4 times a day for 3 days. In rare cases, side effects may develop, which manifest as allergic rashes on the skin.

The drug is contraindicated for patients with liver, kidney and cardiovascular diseases. It is also not used in case of intolerance to the active components.

• Rimantadine

An antiviral agent with the active component rimantadine hydrochloride (adamantane derivative). Its mechanism of action is based on the ability to inhibit the early stage of virus reproduction from penetration into cells to RNA transcription. It is most effective at the initial stages of infectious processes.

• Indications for use: prevention of influenza A virus, tick-borne encephalitis of viral etiology, cytomegalovirus, HPV. Tablets are taken orally, dosage and course of treatment are determined by the attending physician.
• Side effects: decreased concentration and memory impairment, headaches, insomnia, various gastrointestinal disorders, allergic skin reactions.
• Contraindications: intolerance to the components of the drug, impaired absorption of glucose-galactose, lactase deficiency, severe renal and hepatic impairment, thyrotoxicosis. Not used to treat children under 7 years of age, as well as during pregnancy and lactation.

Rimantadine is available as tablets of 10 tablets in a blister, 2 blisters per pack.

The duration of use of tablets depends on the degree of damage, but is usually 4-5 weeks. Despite the fact that most of the described tablets can be purchased without a prescription, you should consult a doctor before using them. This is due to the fact that different drugs behave differently with different strains of HPV.

Particular caution should be exercised when using immunostimulants, as they can disrupt the body's balance at the cellular level.

Injections against human papillomavirus

If topical agents and tablets do not give the desired result in the treatment of papillomatosis, then patients are prescribed injections. This method of treatment allows you to act on the virus from within the body.

• Allokin-alpha

An antiviral drug with pronounced activity against Human papillomavirus, influenza viruses, hepatitis B and C, herpes types 1 and 2. Contains the active substance - alloferon. The active component induces the synthesis of endogenous interferons and activates the immune system. It also promotes recognition and lysis of damaged cells by cytotoxic lymphocytes.

• Indications for use: chronic papillomavirus infection associated with oncogenic strains. The drug can be used as monotherapy in the absence of symptoms of cervical and anogenital lesions. In combination with other antiviral agents, it can be used for recurrent herpes of the second and first type, hepatitis C, B.
• Method of application: the drug is used to prepare a solution for subcutaneous administration. The contents of one ampoule should be dissolved in 1 ml of isotonic sodium chloride solution. For oncogenic HPV, injections are given every 48 hours. In other cases, the dosage and course of treatment are determined by the doctor.
• Side effects: increased weakness, dizziness, skin allergic reactions, pain at the injection site. In case of overdose, more pronounced side effects occur.
• Contraindications: hypersensitivity to the components of the drug, severe autoimmune diseases, pediatric practice. Not used during pregnancy and lactation.

Allokin-alpha is available in the form of lyophilized powder for the preparation of a solution for subcutaneous administration. The drug is available in ampoules of 1 mg each. The package may contain 1, 2, 3, 5 or 10 ampoules.

• Panavir

Antiviral and immunomodulatory agent. 1 ampoule of the drug contains 200 mcg of Solanum tuberosum shoot extract and excipients. The drug increases the non-specific immune response and increases the production of gamma and alpha interferon by blood leukocytes. It has anti-inflammatory and analgesic properties, accelerates regeneration processes at the cellular level.

• Indications for use: diseases caused by Human papillomavirus, herpes type 1 and 2, cytomegalovirus, influenza virus, adenovirus and rhinovirus. Secondary immunodeficiency states against the background of infectious processes in the body. Gastric ulcer and duodenal ulcer, symptomatic ulcers of the gastroduodenal zone, tick-borne encephalitis, prostatitis, arthritis.
• Method of application: the solution is intended for intravenous administration slowly by jet. For HPV, 5 ml of the solution is used every 48 hours, after 3 injections, switch to a dosage of 5 ml every 72 hours. The course of treatment consists of 5 injections.
• Side effects: skin allergic reactions, pain at the injection site.
• Contraindications: individual intolerance to the components of the drug, patients under 12 years of age, pregnancy and lactation.

Panavir is available as a solution for parenteral use in 5 ml vials and ampoules.

Injections for papillomas are considered to be one of the most effective medications that inhibit the replication of the virus and suppress its activation.

Suppositories for human papillomavirus

Very often HPV manifests itself as papillomas and condylomas on the genitals. To treat this problem, it is recommended to use suppositories. Suppositories stimulate the local and general immune system, stop and prevent the growth of skin defects.

• Laferobion

The drug contains an active component - recombinant human interferon (corresponds to interferon a-2b). It has pronounced antiviral, antitumor and immunomodulatory activity, is non-toxic.

• Indications for use: complex treatment of herpes virus, hepatitis B, mixed infections, Human papillomavirus. Also used in the treatment of oncological diseases: skin melanoma, tumors of various localizations, myeloma disease, Kaposi's sarcoma. Therapy of multiple sclerosis.
• Directions for use: 1 suppository 2 times a day, duration of treatment is determined by the attending physician. If necessary, the dosage is adjusted.
• Side effects: muscle and joint pain, local allergic reactions, headache, increased heart rate, nausea, vomiting.
• Contraindications: intolerance to the active component and other components of the drug, pregnancy and lactation, severe liver and kidney diseases.
• Overdose: impaired consciousness, gastrointestinal disorders, headaches. These symptoms are reversible, and drug withdrawal is indicated to eliminate them.

Laferobion suppositories are available in a package of three suppositories. The medication is also available in the form of lyophilized powder for the preparation of injections for intramuscular administration.

• Kipferon

Antiviral, immunomodulatory and anti-inflammatory agent with antichlamydial and antibacterial activity. Rectal and vaginal suppositories contain plasma protein with immunoglobulins G, A and M, as well as human recombinant alpha-2 interferon.

• Indications for use: inflammatory diseases of viral and bacterial origin, acute respiratory diseases, oral and intestinal infections. Chlamydial infections, vulvovaginitis, cervicitis, vaginal microflora disorders, cervical erosion.
• Directions for use: 1-2 suppositories twice daily. Average duration of treatment is 5-14 days.
• Contraindications: hypersensitivity to the components of the drug. The possibility of using the drug during pregnancy is determined by the attending physician.

Kipferon is available in the form of suppositories for intravaginal and rectal use, 5 pieces per package.

• Viferon

A complex preparation with human recombinant interferon alpha-2, ascorbic acid and alpha-tocopherol acetate. It has antiviral, immunomodulatory and antiproliferative effects. It promotes the release of the virus from affected cells and its inactivation by immune agents.

• Indications for use: infectious and inflammatory diseases, acute respiratory viral pathologies, meningitis, sepsis, pneumonia. Chlamydia, herpes, mycoplasmosis, candidiasis, herpes. Papillomavirus infection, hepatitis B, C and D in children and adults, genital herpes.
• Directions for use: 1 suppository 2 times a day, with a 12-hour interval. Duration of therapy is 5-10 days.
• Side effects: skin allergic reactions, urticaria, itching. They pass on their own within 72 hours after discontinuing the drug.
• Contraindications: hypersensitivity to the components of the drug. Use during pregnancy is possible from the 14th week of gestation.

Viferon is available in the form of suppositories for rectal use, 10 pieces per package, and also in the form of an ointment.

• Papillocan

A homeopathic medicine with anti-inflammatory, antipruritic, resolving, analgesic and regenerative effects. It is used to reverse papillomatous lesions of the skin and mucous membranes of the external genitalia and anus. Regulates blood circulation, restores normal tissue trophism. Promotes the appearance of new condylomas and warts.

The suppositories contain thuja and sea buckthorn oil, tea tree oil, homeopathic essence extract (elderberry, cocoa butter, mistletoe). The drug is used after hygiene procedures, 1 suppository for 30 days. It is produced in the form of suppositories for vaginal use. The package contains 10 suppositories.

• Betadine

Antimicrobial and antiseptic agent with an active component - a complex compound of iodine with polyvinylpyrrolidone. It has a pronounced bactericidal effect, also exhibits antiviral, antifungal and antiprotozoal activity. Affects gram-negative and gram-positive pathogens.

• Indications for use: vaginitis caused by mixed or non-specific infection, candidiasis, complex therapy of trichomoniasis.
• Directions for use: insert suppositories deep into the vagina at a dosage of 1-2 pcs. per day for 7-14 days.
• Side effects: local allergic reactions, itching, redness, contact dermatitis. In case of overdose, these reactions become more pronounced.
• Contraindications: hypersensitivity to the components of the drug, pregnancy and lactation, renal and hepatic insufficiency, hyperthyroidism, thyroid adenoma, disorders of the cardiovascular system.

It is available in the form of rectal and vaginal suppositories, 14 pieces per package, and as a 10% solution for external use.

• Polyoxidonium

Immunomodulating and detoxifying agent. Activates killer cells and phagocytic function of blood. Increases formation of immunoglobulins, normalizes immune status in severe immunodeficiency states.

• Indications for use: chronic and recurrent infectious, bacterial and viral diseases. Allergic pathologies, local purulent-septic diseases and postoperative complications, HIV infections.
• Directions for use: 1 suppository 1-2 times a day. The duration of treatment is determined by the attending physician, individually for each patient.
• Side effects: local allergic reactions.
• Contraindications: hypersensitivity to the components of the drug, pregnancy and lactation.

Polyoxidonium is available in the form of suppositories, 10 pieces per package, as well as in ampoules and vials for preparing a solution for injections.

It is almost impossible to cure HPV with suppositories alone. Therefore, suppositories are prescribed in combination with other antiviral drugs.

Ointments for human papillomavirus

Local treatment of HPV symptoms is carried out with ointments. Treatment of affected tissues requires patience. Recovery is long and can take from 1 week to several months.

• Aladara

A topical agent with the active component – imiquimod 5 g. It is included in the pharmacotherapeutic group of immunomodulators for local use, an inducer of interferon synthesis. It has a direct antiviral effect, which is due to the induction of interferon and other cytokines.

• Indications for use: external genital warts on the external genitalia in the perianal area in adults.
• Directions for use: apply the cream externally, in a thin layer, to the previously cleaned surface of the skin growths until completely absorbed. The product is used 3 times a week every other day, the course of treatment is 16 weeks.
• Side effects: itching, pain at the site of application of the cream, infectious complications, erythema, urticaria. Headaches, dizziness, sleep disorders, depressive states, increased irritability, abdominal pain and gastrointestinal disorders.
• Contraindications: patients under 18 years of age, hypersensitivity to the components of the medication. Use of the cream during pregnancy and lactation is possible only as prescribed by the attending physician.

During application, avoid contact of the preparation with healthy tissues, and 3-4 hours after treatment, the condylomas should be washed with warm soapy water.

• Oxolinic ointment

A medicine with the active substance oxolin. It has pronounced antiviral activity against herpetic lesions and the flu virus.

• Indications for use: viral diseases of the skin, eyes, viral rhinitis. Vesicular and herpes zoster, warts, psoriasis, molluscum contagiosum, Duhring's dermatitis herpetiformis.
• Directions for use: externally apply a thin layer to the affected areas 2-3 times a day for 14-60 days. The course of treatment is adjusted by the attending physician.
• Side effects: temporary burning and redness.
• Contraindications: intolerance to the components of the drug.

Oxolinic ointment 0.25% is available in 10 g packages, eye ointment 3% in 30 g tubes.

• Chinese ointment for papillomas San Fen Zhong

Contains acetic and salicylic acid, tea tree extract and mint. Has a cauterizing, bactericidal and antiviral effect. To remove papillomas and warts, the product should be applied to the skin growth, avoiding contact with healthy tissue. After 5 minutes, the ointment is washed off with warm water. The course of treatment consists of 5 procedures.

• Stefanin

A medicinal product with a natural herbal composition. Contains the following components: celandine, common aspen, ivy, field yakutka, spring celandine, burdock and other herbs. The ointment is used to remove any moles, papillomas and warts, even if they are malignant.

The product acts locally and does not penetrate into the systemic bloodstream. After application to a skin defect, it is absorbed into the deep layers of the epithelium, destroys them and pulls them to the surface. Because of this, the growths may increase in size at the beginning of treatment, but gradually they dry out and fall off.

To achieve a lasting therapeutic effect, the ointment should be applied to the skin for a week, then take a 2-3 day break and spend another week of treatment. The period of wart removal depends on their size, location and root depth. On average, treatment takes from 2 weeks to 2-3 months. The ointment is contraindicated for use during pregnancy and lactation, as well as for the simultaneous treatment of 10 papillomas or 5 medium-sized moles.

• Cryopharma

A medicine for removing plantar warts. The drug is a cryotherapy agent, kills viruses and removes skin growths by freezing them. In most cases, it is enough to apply the medicine once and after 10-14 days the affected tissues will begin to die. In especially advanced cases, the therapy is carried out in 2-3 sessions. One package of the drug is designed to treat 12 warts.

• Dermavit gel

An external agent for safe removal of papillomas and warts. It has a unique composition that eliminates skin defects without leaving scars or other marks. The medicine is applied to the affected tissues daily for 7-10 days until the treated surface darkens. In case of increased skin sensitivity, papillomas can be treated every other day.

Some patients report burning and itching in the treated area. The gel is contraindicated for use in treating skin growths on the face, armpits and genitals. You should also avoid getting the gel on healthy tissue and mucous membranes.

Ointments for papillomatosis should be used with extreme caution. Most preparations contain active components that, when they come into contact with healthy tissue, cause pathological changes.

Isoprinosine

Immunostimulating and antiviral agent. Contains the active substance - 500 mg inosine pranobex (inosiplex). Increases the total number of T-lymphocytes and increases their production. Blocks the replication of viral DNA by damaging the genetic apparatus of viral particles.

Stimulates macrophage activity, activates cytokine formation and lymphocyte proliferation. Helps reduce clinical signs of viral diseases, increases the body's resistance.

• Indications for use: diseases caused by Human papillomavirus, measles virus, herpes types 1 and 2, Epstein-Barr virus and mumps. Also used for viral bronchitis, acute or chronic hepatitis B and C, subacute sclerosing panencephalitis, infectious pathologies of the respiratory and urinary systems.
• Method of administration: orally 50 mg/kg of body weight, divided into 3-4 doses. Duration of treatment is 10-15 days with a repeat course after a week.
• Side effects: headaches and dizziness, increased weakness, dyspeptic phenomena, increased transaminase activity, changes in the level of uric acid in the urine and blood. In case of overdose, side effects are aggravated. Symptomatic therapy and drug withdrawal are indicated to eliminate them.
• Contraindications: renal failure, cardiac arrhythmia, intolerance to the active components of the drug, pregnancy and lactation, gout, urolithiasis.

Isoprinosine is available as tablets for oral use, each containing 500 mg of active ingredient.

Gardasil

A vaccine for the prevention of infection with papillomavirus types 6, 11, 16 and 18. Activates the body's immune system and promotes the formation of antiviral immunoglobulins. Provides long-term immunological protection against HPV and cross-protection against a number of highly oncogenic strains: 31, 33, 35, 45, 51, 52, 58, 59.

Each vial of the preparation contains the following substances: Human papillomavirus antigens (L1 protein) types 6 and 18, 20 mcg each, types 11 and 16, 40 mcg each. Auxiliary components of the vaccine are: aluminum hydroxyphosphate sulfate amorphous, sodium chloride, L-histidine, polysorbate-80, sodium borate, prepared sterile water.

• Indications for use: prevention of HPV infection and prevention of precancerous conditions. The drug is used to vaccinate patients aged 9 to 45 years.
• Directions for use: the vial with the preparation is checked for foreign inclusions, shaken thoroughly and drawn into a syringe. The medicine is administered intramuscularly using a needle inserted into the complex with the vaccine vial. The intramuscular injection is made into the delta of the shoulder or the anterolateral region of the thigh. After vaccination, the patient should be under medical supervision for 20-30 minutes. Vaccination consists of three stages. The standard scheme is 0-2-6 months and the accelerated scheme is 0-1-4 months.
• Side effects: painful sensations, itching, burning and hyperemia at the injection site. Headaches, inflammatory reactions in the pelvic organs, thromboembolism, fever and fainting, joint pain, myalgia. In case of overdose, the above reactions become more pronounced.
• Contraindications: intolerance to vaccine components, blood clotting disorders, pregnancy and lactation, pediatric patients, course of treatment with anticoagulants.

Gardasil is available in suspension vials. Each vial contains a single dose of the drug - 0.5 ml of solution.

Cycloferon

Immunomodulatory and antiviral agent. The drug is a high-molecular inducer of endogenous interferon formation. Its effectiveness is due to a wide range of biological activity:

• Anti-inflammatory
• Antiviral
• Immunomodulatory
• Antitumor
• Antiproliferative action.

The medicine is available in several forms, each form contains the active ingredient - acridoneacetic acid and excipients.

• Indications for use: herpes infections, acute respiratory diseases, acute intestinal infections, neuroinfections, secondary immunodeficiency, viral and chronic hepatitis B and C, HIV in clinical stage 2A-3B. Systemic diseases of connective tissue and rheumatic pathologies, neuroinfections, cytomegalovirus. The drug in the form of an ointment is used to treat herpes rashes, vaginosis, bacterial vaginitis, balanoposthitis, urethritis, candidiasis.
• The method of administration and dosage depend on the form of the medication, therefore they are determined by the attending physician for each patient individually.
• Side effects: allergic reactions. No cases of overdose have been recorded.
• Contraindications: hypersensitivity reactions to the components of the drug. Injections are not used in decompensated liver cirrhosis. Treatment during pregnancy and lactation is also prohibited.

Cycloferon is available in several forms: enteric-coated tablets, injection solution in 2 ml ampoules, liquid ointment - 5% cycloferon liniment in 5 ml tubes.

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Amiksin

Low-molecular synthetic interferon inducer. Each tablet contains 60 or 125 mg of the active substance - tilorone. Stimulates the synthesis of interferons of type a, b, g, as well as the growth of stem cells. Characterized by a mild immunomodulatory effect and a pronounced antiviral effect.

• Indications for use: herpes, viral hepatitis, cytomegalovirus infection, complex therapy of tuberculosis, influenza and acute respiratory viral infections, respiratory and urogenital chlamydia, viral and infectious-allergic encephalomyelitis.
• Method of administration: orally after meals. The dosage is determined by the attending physician for each patient individually. On average, the drug is taken 1-2 capsules once a day for 2 days, and then the dosage is reduced by half and taken for another 2 days.
• Side effects: digestive system disorders, dispersion, allergic reactions of the skin, temporary chills and fever. Overdose is manifested by an increase in the above reactions, treatment is symptomatic.
• Contraindications: hypersensitivity to the components of the drug, pregnancy and lactation, patients under 7 years of age.

Amixin is available in tablet form, the package contains 6, 10 tablets of the drug.

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Acyclovir

An antiviral drug with the active ingredient 9-(2-Hydroxy) ethoxymethylguanine. It is effective against herpes and papillomatous viruses.

• Indications for use: prevents the appearance of new skin growths and reduces the likelihood of their dissemination, accelerates the healing process in herpes in the acute zoster form. The immunostimulating effect of the drug helps to activate the body's defenses.
• Method of application: orally, locally or intravenously. Tablets are used for lesions of the skin and mucous membranes, injections for severe forms of the disease, and the ointment is applied to skin lesions. The course of treatment is determined by the attending physician for each patient individually.
• Side effects: when taken orally, nausea and vomiting, stool disorders, headaches, skin allergic reactions, increased fatigue are possible. Intravenous vision leads to an increase in the level of urea, bilirubin and creatinine in the blood serum, contributes to an increase in the activity of liver enzymes.
• Contraindications: hypersensitivity to the components of the drug, pregnancy and lactation.

The drug is available in several forms: tablets, vials with dry substance for injections, eye ointment and cream.

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Groprinosin

A medicinal product with the active component – inosine pranobex 500 mg. Suppresses the synthesis of RNA viruses, providing a pronounced antiviral effect. Promotes activation of cytokine synthesis and enhancement of the immunomodulatory effect. Affects the transformation of T-lymphocytes, stimulates mitosis and proliferation of B and T lymphocytes.

In the presence of viral agents in the body, it accelerates the production of immunoglobulins, reducing objective and subjective signs of infection. It has a complex effect on the immune system, reduces the viral load, increases the synthesis of endogenous interferon, increasing the body's resistance to viral infections.

• Indications for use: treatment of viral infections in patients with normal or reduced immune status. Prescribed for diseases caused by HPV, acute respiratory viral infections, viral bronchitis, herpetic lesions, Epstein-Barr virus, cytomegalovirus, hepatitis B. The drug is effective for infections of the genitourinary and respiratory systems caused by intracellular pathogens.
• Method of administration: tablets are taken orally after meals with plenty of liquid. The duration of treatment is individual for each patient and depends on the severity of the disease. On average, the medication is taken for 1-2 weeks with a repeat course after 7-10 days. If necessary, therapy can last from 1 to 6 months. For HPV, take 2 capsules 3 times a day, the course of treatment is 2-4 weeks.
• Side effects: transient increase in uric acid levels, loss of appetite, nausea, vomiting, pain in the epigastric region, bowel disorders, increased transaminase levels, skin rashes, sleep disorders, headaches. Overdose is manifested by increased side effects.
• Contraindications: intolerance to inosine and other components of the drug, pregnancy, lactation, urolithiasis, terminal stages of chronic renal failure.

Groprinosin is available in the form of tablets of 500 mg of active ingredient each, 20 and 50 capsules per package.

Surgical treatment

The human papilloma virus most often manifests itself in such growths: papillomas, warts, condylomas. They are localized not only on the skin, but also on the mucous membranes. They can be of different sizes, shapes and colors.

Very often, skin deformities are injured, causing pain and increasing the risk of infection. Surgical treatment is an effective method aimed at removing pathological growths.

There are the following methods of surgical treatment of papillomatosis:

1. Laser destruction – growths are removed using a laser beam. This method is characterized by the least trauma. The laser sutures the blood vessels that feed the papillomas. The step-by-step removal of the affected tissues does not affect the healthy layers. There are no scars after the procedure. Complete healing takes about 2-3 weeks.
2. Surgical operation – removal of neoplasms is performed under local anesthesia using a scalpel. A special patch and bandage are applied to the operated tissues. After such treatment, scars and marks remain. Another disadvantage of the method is the risk of bleeding during surgery and incomplete removal of infected cells.
3. Cryodestruction – the removal of growths is carried out using liquid nitrogen. The procedure involves freezing the growths, which then fall off on their own. The disadvantage of this method is that it is difficult to control the depth of the freezing effect. Too deep a nitrogen lesion causes serious scars, and insufficient effect requires a repeat procedure.
4. Radio wave surgery – papillomas are cut off using a radio wave knife. The procedure is performed under local anesthesia so that the patient does not experience pain. This method is highly accurate. There are no burns or other complications after it.
5. Electrocoagulation – the affected tissues are exposed to electric current, which destroys the cells affected by HPV. High-frequency current causes protein tissue to coagulate and cauterizes the resulting wound. This method has a low risk of bleeding and subsequent infection.

Removal of neoplasms is performed by a surgeon or cosmetologist. This treatment method is suitable for patients of all ages.

How to live with the human papillomavirus?

Modern methods of treating the papilloma virus allow to suppress its active course and spread. With the help of various surgical techniques, it is possible to get rid of skin manifestations of papillomatosis, which cause aesthetic discomfort and very often lead to psychological problems.

If the detected virus has medium or increased oncogenicity, the patient will undergo an extended course of treatment, which consists of taking antiviral, immunostimulating, anti-inflammatory and a number of other drugs. In case of malignant tumors, conservative therapy and surgery are carried out to remove the affected tissues in combination with exposure to oncogenic cells (radiation, chemotherapy).

Although it is impossible to completely get rid of the virus, a comprehensive treatment approach allows it to remain dormant for a long time. Thanks to this, the patient can lead a full, healthy lifestyle, without forgetting about maintaining the immune system.

Self-healing from human papillomavirus

When faced with a problem such as papillomatosis, some patients report self-healing from the virus. Such cases do occur, but they only relate to infection with strains with low oncogenicity.

In this case, the self-elimination of the infection indicates a strong immune system that has suppressed pathogens. It should also be taken into account that the virus can remain dormant in the body for a long time. HPV prevention in combination with strengthening the immune system will not allow it to become active.