Hepatic Peliolium: Causes, Symptoms, Diagnosis, Treatment
Last reviewed: 23.04.2024
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Hepatic periosis is the most commonly asymptomatic disease in which multiple, blood-filled cystic cavities are randomly produced in the liver.
With hepatic pelosis, cysts measuring from a few millimeters to 3 cm in diameter are usually devoid of endothelial lining and are surrounded by hepatocytes. Some cysts have endothelial lining and develop from enlarged sinusoids of the liver. This may be due to damage to the cell lining of the sinusoids. The development of hepatic encephalopathy is associated with hormones (anabolic steroids, oral contraceptives, glucocorticoids), tamoxifen, vinyl chloride, vitamin A and azathioprine (imunane), especially in patients after kidney transplantation.
Hepatic periosis is usually asymptomatic, but is sometimes complicated by ruptured cysts with bleeding (sometimes fatal) or by the development of an obvious liver pathology characterized by jaundice, hepatomegaly and liver failure. Asymptomatic cases can only be detected by accident, based on small changes in functional liver tests or ultrasound.
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