The most common causative agents of pneumonia are gram-positive and gram-negative bacteria, intracellular pathogens, and, less frequently, fungi and viruses. In young people, pneumonia is often caused by a single pathogen (monoinfection), whereas in elderly patients and in people with concomitant diseases, pneumonia is often caused by bacterial or viral-bacterial associations (mixed infection), which creates serious difficulties in selecting adequate etiotropic treatment.