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Densitometry

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Last reviewed: 07.06.2024
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Densitometry is an examination method used to assess bone density and bone quality. The main purpose of this study is to determine the condition of the bones and detect the presence of osteoporosis or other bone diseases. Densitometry can be performed in different parts of the body, but the most common areas to be examined are the spine, hips, and forearm.

The essence of the densitometry procedure is to measure the amount of minerals, mainly calcium, in the bones. This measurement makes it possible to determine bone density and compare it with the norms for a certain age and sex group. The results of densitometry are usually expressed as a T-count and Z-count:

  1. T-count: Compares a patient's bone density to that of young adults, expressed in standard deviations (SD). Normal T-count values are usually above -1.0 SD. Values below this indicate decreased bone density and a risk of osteoporosis.
  2. Z-score: Compares a patient's bone density to the bone density of people of their age group and gender.

Densitometry is a safe and non-invasive procedure. It is usually performed in clinics or health care facilities and can take only a few minutes. This test method is an important tool for diagnosing osteoporosis and assessing the risk of bone fractures, especially in postmenopausal women and older patients.

A doctor who specializes in performing and interpreting densitometry is usually called a "densitometrist" or "densitometrologist". He or she has specialized medical training and experience in assessing bone density using densitometry.

Duties of the densitometry physician include:

  1. Performing Densitometry: The densitometrist performs the densitometry procedure itself, which may involve scanning the patient using X-rays (DXA) or ultrasound waves (USW) depending on the type of equipment.
  2. Interpretation of results: After the study is complete, the doctor analyzes the data and interprets the results. This includes calculating the T-count and Z-count, as well as determining whether there is osteoporosis, osteopenia, or normal bone mass.
  3. Diagnosis and Recommendations: Based on the results of densitometry, your doctor may make a diagnosis of osteoporosis or osteopenia and provide recommendations for further treatment and bone health management. This may include prescribing medications, physical activity and diet.
  4. Monitoring: A densitometrist may also perform monitoring of patients with osteoporosis or osteopenia to track changes in bone density and the effectiveness of treatment.
  5. Education and counseling: The physician may educate patients about the importance of bone health, talk about risk factors, and provide counseling on osteoporosis and fracture prevention.

For consultation or densitometry, you may see a densitometrist, rheumatologist, endocrinologist, or other specialist who specializes in osteoporosis and bone disease.

Indications for the procedure

Densitometry is a method of assessing bone density and can be used for the following indications:

  1. Diagnosis of osteoporosis: Densitometry is one of the main methods for diagnosing osteoporosis. This method assesses the density of the bones and determines how much they are at risk of fracture.
  2. Monitoring osteoporosis treatment: Patients with osteoporosis receiving treatment may undergo densitometry regularly to assess the effectiveness of treatment and changes in bone density.
  3. Fracture risk assessment: Densitometry can be used to assess a patient's overall fracture risk, especially in postmenopausal women and those with risk factors for osteoporosis.
  4. Investigation of bone diseases: Densitometry can be performed to diagnose various bone diseases such as osteopenia, osteomalacia, etc.
  5. Assessing bone health after fractures: Densitometry can be used to assess the health of bones after fractures and determine how much they have recovered.
  6. Bone monitoring in chronic diseases: Patients with chronic diseases such as multiple sclerosis or rheumatoid arthritis may experience loss of bone mass. Densitometry can be used to monitor this process.
  7. Bone assessment in people taking certain medications: Some medications can affect bone mass. Densitometry can be used to assess bone in patients taking such medications.

Preparation

Preparation for densitometry is usually quite simple and does not require specific measures, but it is important to follow some guidelines:

  1. Clothing: Come to the study wearing comfortable clothing that does not contain metal parts. It is best to wear lightweight clothing without metal buttons, zippers, or clasps.
  2. Jewelry and metal objects: Remove all jewelry and objects containing metal (such as bracelets, necklaces, pins, and even coins) before the study, as they may affect the results.
  3. Food and Drink: Normally, densitometry can be performed without any restrictions on food and drink. However, if you are given any specific instructions from your doctor or laboratory, follow them.
  4. Makeup products: If you use makeup products on areas that will be scanned (such as the face), make sure they do not contain metallic particles.
  5. Medications: If you are taking any medications, be sure to tell the doctor or technician performing the study. Some medications may affect the densitometry results and the doctor will need to take this into account.
  6. Pregnancy: If you are pregnant or suspect you may be pregnant, tell your doctor before the test. In some cases, densitometry may not be appropriate during pregnancy.
  7. Compliance with instructions: It is important to follow the instructions of the physician or laboratory performing the densitometry and fulfill their preparation recommendations.

The device for carrying out the procedure

Specialized machines called densitometers are used to perform densitometry.

The most common types of densitometers are:

  1. DXA (Dual-beam X-ray absorptiometry): This method uses two X-ray beams of different energies that pass through bone. Based on the difference in absorption between bone and soft tissue, an image is constructed and bone density measurements are taken.
  2. QCT (Quantum Calibrated Computed Tomography): This method also uses computed tomography, but with calibration based on material density data. It allows the estimation of bone density and the volume of minerals in the bones.
  3. pQCT (Peripheral Computed Tomography): This method is designed to measure bone density in peripheral bones, such as the bones of the forearm or hip.
  4. HR-pQCT (High Resolution Peripheral Computed Tomography): This method provides higher resolution and allows for a more detailed study of bone microstructure.

Densitometry is usually performed in specialized medical centers or clinics using appropriate equipment.

Ultrasound densitometry (USD)

It is a method of assessing bone density that uses ultrasound waves instead of X-rays, as in the case of classical densitometry (DXA). Ultrasound is a safe and non-invasive examination method that can be used to assess bone density in different parts of the body, usually in the bones of the forearm (anterior radius) or metacarpal bones.

Here are some of the characteristics of ultrasonic densitometry:

  1. Safety: Ultrasound densitometry does not use ionizing radiation, making it safe for all patients, including pregnant women.
  2. Speed and simplicity: This test method is usually quick and requires little patient preparation. It can be performed in a clinic or health care facility.
  3. Applicability: USD is most often used to assess bone density at peripheral skeletal sites, such as the forearm, where ultrasound transduction is more effective. It can be useful for diagnosing osteoporosis or assessing fracture risk in these areas.
  4. Less accurate than DXA: USG may be less accurate than classical densitometry (DXA), especially in assessing bone density in central skeletal regions such as the spine and hips. Therefore, DXA remains a more accurate method for diagnosing osteoporosis and assessing overall bone health.

USD can be useful for initial screening and monitoring of bone density, especially when DXA is not possible or when specific peripheral bones need to be evaluated. However, to accurately diagnose and monitor osteoporosis, it is important to consider all clinical and laboratory findings in conjunction with ultrasound or other testing methods.

Technique of the densitometry

Densitometry is a method of measuring bone density that is often used to diagnose osteoporosis and assess the risk of bone fractures. Here is a general technique for performing densitometry:

  1. Preparing for the procedure:

    • Densitometry is usually performed on a special machine called a densitometer. The patient does not need any special training.
    • However, it is important to make sure that the patient is not wearing metal clothing, jewelry, or other metal accessories that may interfere with the scan.
  2. Execution of the procedure:

    • The patient usually lies down on the table for densitometry.
    • The patient may be asked to remain still during the procedure.
    • During a scan, the densitometer sends X-rays through the bone tissue and measures how much radiation passes through the bone. These measurements are used to calculate bone density.
  3. Completion of the procedure:

    • The densitometry procedure is usually completed quickly. The patient can return to normal activities immediately after the procedure and no recovery period is required.
  4. Results:

    • The data obtained is analyzed by a specialist who assesses bone density and performs the appropriate calculations.
    • Densitometry results are presented as a T-score and Z-score, which are compared to normal bone density for a specific age group.

Densitometry is a safe and non-invasive procedure, and it can assess bone health and the risk of osteoporosis.

Lumbar spine and femoral neck densitometry is one of the most common types of densitometry and is used to assess bone density in these key areas of the body. This type of study can be useful in diagnosing osteoporosis and assessing the risk of bone fractures.

In a spine and femoral neck densitometry procedure, the patient usually lies on a table and a special device scans the specified areas using X-rays (DXA) or ultrasound waves (USG). The bone density values in these areas are then measured and the results are presented as a T-count (comparison to young adults) and Z-count (comparison to patients of your age and gender).

The primary goals of spine and femoral neck densitometry include:

  1. Diagnosing osteoporosis: The study can help doctors detect the presence of osteoporosis or osteopenia (a precautionary condition) in the early stages, when there are no fractures yet.
  2. Fracture risk assessment: Bone density in the spine and femoral neck is strongly correlated with fracture risk in these areas, especially in older patients. Low bone density may indicate a higher risk of fracture.
  3. Treatment Monitoring: If a patient already has a diagnosis of osteoporosis or osteopenia and is receiving treatment, spine and femoral neck densitometry can be used to monitor the effectiveness of treatment and assess changes in bone density.
  4. Comparison of results over time: Repeated spine and femoral neck densitometry studies can help physicians track changes in bone density over time and assess the risks or effectiveness of preventive measures.

Pediatric densitometry

Densitometry can be performed on children, but it is usually only recommended in certain cases and for medical reasons. The main reasons for densitometry in children include:

  1. Bone Mass Assessment: Densitometry may be performed to assess bone mass in children at risk for osteoporosis or osteopenia, for example, if there is a family history of these diseases.
  2. Diagnosis of bone disorders: Children can have a variety of bone disorders such as osteogenesis irregularis type I, osteogenesis irregularis type II, rickets, hypophosphatasia, and others. Densitometry can help doctors in diagnosing and monitoring these conditions.
  3. Assessment of treatment efficacy: For children receiving treatment for bone disease, densitometry can be used to assess treatment efficacy and monitor changes in bone mass.

The densitometry procedure for children is similar to that for adults and can be performed using dual-energy X-ray absorptiometry (DXA) or ultrasound densitometry (USD). It may be more difficult in young children as they may have difficulty remaining still during the procedure.

Before densitometry is performed on your child, it is important to discuss it with your pediatrician or pediatric endocrinology specialist. They can evaluate the medical conditions and decide if densitometry is necessary and safe for your child.

Contraindications to the procedure

Densitometry is a relatively safe procedure and there are no contraindications in most patients. However, in rare cases, there may be some limitations or conditions in which densitometry may require caution or further consultation with a physician. Here are some of the possible contraindications or limitations:

  1. Pregnancy: Densitometry using X-rays is generally not recommended for pregnant women, especially in the first trimester when there is an increased risk of fetal exposure to radiation. If densitometry is necessary, your doctor may consider alternative methods that do not involve X-rays.
  2. Presence of metal implants: The presence of large metal implants, such as artificial joints or plates, in the area to be examined may distort the results of densitometry.
  3. Infectious Disease or Open Wounds: If a patient has an infectious disease or open wounds in the area to be examined, densitometry may require caution to prevent the spread of infection.
  4. Severely obese: In severely obese patients, densitometry results may be less accurate because fatty tissue can distort the measurements.
  5. Need for X-ray contrast agents: In rare cases where densitometry with contrast agents is performed, caution may be required in patients with allergies to contrast agents or renal dysfunction.

Normal performance

Normal densitometry values may vary slightly depending on the specific method and equipment used to perform the study, as well as the patient's age, gender, and ethnicity. However, general values for assessing bone density are usually expressed as T- and Z-scores:

  1. T-score: This score compares a patient's bone density to that of a young healthy person of the same sex. The T-score is usually expressed as standard deviations from the mean for young adults. A normal T-score is usually above -1.0. Values less than -1.0 may indicate a risk of osteoporosis.
  2. Z-score: This score compares a patient's bone density to that of people of the same age, sex, and ethnicity. The Z-score takes into account the natural variation in bone density with age.

It should be noted that T-score is commonly used to diagnose osteoporosis. Here is the interpretation of the T-score:

  • Above -1.0: Normal bone density.
  • -1.0 to -2.5: Osteopenia (low bone density, which can be a precursor to osteoporosis).
  • Below -2.5: Osteoporosis.

T-score values below -2.5 indicate a more serious risk of osteoporosis and may require treatment.

Deciphering densitometry results

Specialized medical education and experience is usually required to properly decipher the results of densitometry (DXA or USG). Densitometry results are presented in a variety of values and graphs, which may include the following indicators:

  1. T-count(T-score): This is a basic score that compares your bone density to that of young adults (average peak bone mass). The T-count is expressed as standard deviations (SD) from the mean. Normal T-count values are usually above -1.0 SD. If the T-count is less than -1.0, it may indicate osteopenia (decreased bone density) or osteoporosis.
  2. Z-score: This score compares your bone density to the bone density of people of your age and sex. It can help detect abnormalities in bone mass development in children and young adults.
  3. Fracture area: This score assesses total bone area and may indicate fracture risk.
  4. T-count or Z-count graph: A graph can visualize changes in bone density in different areas of the body, such as the spine, hips, and forearm. The graph can show where specific areas with reduced bone mass are located.

Deciphering your densitometry results requires comparing your scores to the norms for your gender and age group. Assessing your fracture risk and osteoporosis diagnosis may also involve analyzing other factors such as age, gender, presence of risk factors (e.g., family history, smoking, alcohol consumption), and clinical data.

Complications after the procedure

Densitometry is a common and safe procedure to measure bone density. However, as with any medical procedure, rare complications can occur. Here are some of the possible complications:

  1. Radiation Exposure Risk: Densitometry relies on the use of X-rays, and although the radiation dose used in this procedure is very low, some people may be more sensitive to radiation. In most cases, the radiation dose is not high enough to cause any significant effects.
  2. Allergic reactions: If you are injected with a contrast agent during densitometry (e.g., for a spine scan), it is possible to have allergic reactions to the contrast agent. This is, however, a rare occurrence.
  3. Danger to pregnant women: Densitometry using X-rays is not recommended for pregnant women, especially in the first trimester, because of potential risks to the fetus.
  4. Injury: Patients who have limited mobility or difficulty moving may be at risk of injury when moving on the densitometry table or attempting to change posture during the procedure. Therefore, it is important to notify medical staff of any mobility limitations or medical conditions prior to the procedure.
  5. Other complications: Although extremely rare, other complications related to the equipment and the densitometry procedure may also occur.

Care after the procedure

No special care or restrictions are usually required after a densitometry procedure. It is a minimally invasive and safe study. However, there are a few general recommendations:

  1. Return to normal activities: After the densitometry is completed, you can return to your normal activities without any restrictions. The procedure leaves no physical residue behind.
  2. Nutrition and hydration: Continue to consume food and water according to your normal needs. Densitometry does not require special dietary restrictions.
  3. Removing marker residue: If you have been given markers or markings on the skin to accurately localize the scan, you can remove them after the procedure. Use common marker removers such as cotton pads with medical alcohol.
  4. Monitor yourskin: If you have any skin reaction to contact with the sensors or densitometer table surface (e.g., redness or irritation), you may apply moisturizer or cooling gel to relieve discomfort. However, such reactions are extremely rare.
  5. Consult yourdoctor: If you experience any unusual symptoms or sensations after the procedure, consult your doctor. Although densitometry is generally safe, it is always important to monitor the

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