The norm of the coagulogram is very important. The fact is that the analysis should correspond to some acceptable figures. Any deviation indicates the presence of problems in the human body. More details about this issue can be found below.
The normal coagulogram indices in the table include the optimal indicators. So, when analyzing as a result, a person gets several digits. Among them are APHT, Fibrinogen, Lupus coagulant, Platelets, Prothrombin, TV, D-Dimer and Antithrombin III.
If it is an extended analysis, then these indicators are attributed to the following: Prothrombin time, Protein S, Protein C and Willebrand Factor.
All these "elements" must have certain numbers. They indicate that everything is normal, or has a slight deviation. In normal form, the indicators should be as follows:
up to 6,5 g / l
should be absent
131-402 thousand / μL
33-726 ng / ml
For any deviation, the coagulogram norm is not similar to the data given. This phenomenon requires clarification of the cause and elimination of the problem itself.
Coagulogram parameters are normal in the case when there are no negative processes in the human body. Moreover, if the patient does not take indirect coagulants, then the change in the basic "elements" is simply impossible.
If there are any deviations, then the cause must be determined without fail. The fact is that the reduction of some indicators can lead to thrombosis, which is especially dangerous for a person. If it is a pregnant girl, then any deviation can trigger not only the formation of thrombi, but premature detachment of the placenta. Therefore, the norm of the coagulogram should always be seen, this will avoid serious complications.
Coagulogram norm INR
The norm of the coagulogram depends on many indicators. So, this "element" is the calculated data, due to which it is possible to know the ratio of prothrombin time of the patient to the average prothrombin time. This indicator is necessary for the treatment of indirect coagulants.
The fact is that these medications can worsen blood clotting and lead to serious problems. Patients who are on similar therapy should follow the INR indicator.
Normally, this "element" is less than 1.25. If the figure is underestimated or overestimated, it is necessary to search for the cause of this phenomenon. Basically, a sharp drop in the INR indicates a lack of effect that anticoagulants give, which requires some intervention. This process can lead to a significant risk of thrombus formation. The norm of the coagulogram of the INR indicator should not fluctuate, because otherwise it harms the body and most likely the negative process has already begun.
The rate of fibrinogen
The norm of a coagulogram fibrinogen in case of a violation can lead to increased bleeding. Under this indicator, a specific protein is hidden. It refers to the main component of the thrombus, which is able to form during clotting. Fibrinogen, by virtue of its qualities, is responsible for many functions regarding the clotting process.
This indicator fluctuates most during pregnancy, and there is nothing to worry about. But all the same, a woman should be under the supervision of a doctor. After all, in some cases this may indicate the presence of an inflammatory process or the risk of developing cardiovascular complications. All this can occur against the background of increased coagulability of blood, which is not the norm. In general, this indicator should not exceed 6.5 g / l.
With a significant decrease in it is possible the development of severe bleeding, which can carry an innate character. Observe the "element" is during pregnancy, and pay special attention to this moment. After all, the norm of the coagulogram of this indicator should be observed.
The norm of coagulogram PTI
The norm of the coagulogram of birds is the ratio of the clotting time of normal plasma to the time of clotting of the patient's plasma. This number should be expressed in percentages and not exceed 78-142%.
This indicator is able to increase, but only if there is a risk of developing blood clots. The specified number decreases with a tendency to bleeding. That's why he needs to pay special attention.
It should be noted that in pregnant women this indicator is able to vary slightly and this is the norm. However, this may be due to premature detachment of the placenta.
An increase in the index indicates the presence of increased coagulability of the blood. This is not very good, because it can lead to the development of cardiovascular diseases. In some cases, the indicator varies due to the prolonged intake of oral contraceptives. In any case, the true cause of this phenomenon should be determined. The norm of the coagulogram of prothrombin index should be observed.
The norm of the coagulogram rfmk depends on a lot. Basically, this indicator is necessary in order to determine the amount of soluble complexes in the blood.
These "elements" are markers of thrombinemia with intravascular coagulation. Determine this indicator can only be manual. Naturally, the procedure is not complicated and is carried out rather quickly. Ideally, there should not be any complexes in the human blood.
RFMK is not at all mandatory. Rather, it is done before a serious surgical intervention. This indicator is taken from the blood, which was submitted for analysis. The higher the concentration of complexes in it, the higher the risk of intravascular thrombosis. Therefore, RMMC plays a significant role.
Its decrease indicates the treatment with heparin. This is quite effective when it is necessary to prescribe heparin prophylaxis or heparin therapy. RFMC coagulogram norm should not go beyond 0-0.4.
The norm of the coagulogram D dimer
The norm of the coagulogram dimer plays a significant role. Thus, this indicator is a product of the breakdown of fibrin. It shows violations of the process of blood clotting. This element is especially important in the diagnosis of thrombosis, pregnancy and cancer.
Dimer has always been considered a specific degradation product, which is part of the thrombus. According to these data, it is possible to monitor the intensity of the processes of formation and destruction of fibrinous clots.
Many factors can affect this indicator. The definition of the dimer level is considered specific. Its level depends on the presence of pathological conditions that can be accompanied by enhanced fibrinolysis. These include various kinds of infections, wound healing, hemorrhagic complications, and the like. Normally, Dimer does not exceed 33-726 ng / ml. If there are any violations, then they must necessarily be rendered harmless. Because the norm of the coagulogram of this indicator should be fully observed.
Norm of coagulogram MI
The norm of coagulogram of PV is one more important indicator. Prothrombin time is an "element" that reflects the rate of blood clotting. It is used to diagnose diseases of the coagulating system of blood. In addition, it allows you to evaluate the effect of drugs that are aimed at impairing the ability of coagulation.
Normally this should not be more than 10-13 seconds. Any deviation indicates the presence of pathological processes in the body. Above the norm indicates that there is a low concentration of clotting factors, a lack of vitamin K, as well as liver disease or a violation of its functions.
It is likely that we are talking about the presence of the syndrome of disseminated intravascular coagulation. This condition can endanger life, because it does not allow blood to quickly clot, which can lead to a complete non-stop of bleeding. The increase in prothrombin time is not a good process. If surgical intervention is necessary, the coagulogram norm for this indicator should be observed.
Norm of coagulogram in pregnancy
The norm of a coagulogram during pregnancy should be observed without fail. The fact is that any deviations may indicate serious problems in the body, including early detachment of the placenta, which is extremely unacceptable.
In some cases, deciphering the received data is not so simple. It is advisable to leave it to the doctors. Despite the fact that the indicators can fluctuate significantly during pregnancy, they should not go beyond acceptable limits. So, they have the following form: APTTV - 17-20 s; Fibrinogen - up to 6,5 g / l; Lupus anticoagulant - should be absent; Platelets - 131-402 thousand / mkl; Prothrombin - 78-142%; Thrombin time is 18-25 s; D-dimer - 33-726 ng / ml; Antithrombin III - 70-115%.
If the received data differ from these figures, appropriate measures must be taken. After all, all this can negatively affect the development of the fetus. Childbirth suggests the loss of a small amount of blood. With poor coagulation, this is simply unacceptable. Therefore, the norm of the coagulogram should be observed.
Norm of coagulogram in children
The norm of the coagulogram in children practically does not differ from the adult indices. Thanks to this analysis, it becomes possible to determine the ability of the blood to rapidly coagulate. The procedure for children is not so often, mostly just before surgery.
In some cases, the analysis is done even with minor procedures. This will avoid all possible complications and make sure that the properties of platelets are working in full measure. Any abnormalities can lead to clogging of the vessels. Often a coagulogram is performed if there is a suspicion of blood pathologies.
Normally, the indicators should not go beyond the following: APTTV - 17-20 s; Fibrinogen - up to 6,5 g / l; Lupus anticoagulant - should be absent; Platelets - 131-402 thousand / mkl; Prothrombin - 78-142%; Thrombin time is 18-25 s; D-dimer - 33-726 ng / ml; Antithrombin III - 70-115%. Such data is considered standard. The norm of the coagulogram should fully meet the declared parameters.
Last update: 01.06.2018
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Medical expert editor
Portnov Alexey Alexandrovich
Education: Kiev National Medical University. A.A. Bogomolets, Specialty - "General Medicine"
When fibrin fibers are cleaved, fragments are formed-D-dimers. When determining the content of D-dimers with the help of specific antisera, one can judge to what extent fibrinolysis, but not fibrogenolysis, is expressed in the test blood. The increased content of D-dimer is one of the main markers of activation of the hemostasis system, since it reflects both the formation of fibrin in the blood under study, and its lysis.
The degradation products of fibrinogen / fibrin are formed in the body upon activation of the fibrinolysis system (interaction of plasmin with fibrinogen and fibrin), which develops in response to intravascular fibrin formation. The degradation products of fibrinogen / fibrin have antithromboplastin, antithrombin and antipolymerase action.
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