^

Health

A
A
A

Berylliosis of the skin

 
, medical expert
Last reviewed: 07.07.2025
 
Fact-checked
х

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.

We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.

If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.

Berylliosis is a systemic occupational disease with predominant damage to the respiratory system, which is based on the formation of typical immune granulomas from the introduction of metals. Beryllium granulomas in the skin develop as a result of beryllium entering through damaged skin, less often - hematogenously. Clinically, the lesions look like small or large-nodular, bluish or yellowish-red formations, similar to those in sarcoidosis. Ulceration may occur. Skin tests with beryllium are usually sharply positive.

trusted-source[ 1 ], [ 2 ], [ 3 ], [ 4 ], [ 5 ], [ 6 ]

Pathologists of berylliosis

Skin granulomas in systemic berylliosis are indistinguishable from granulomas in sarcoidosis, since they are almost not subject to necrosis. Beryllium particles are usually not visible in histological sections, but they are detected by spectrography.

What do need to examine?

How to examine?

You are reporting a typo in the following text:
Simply click the "Send typo report" button to complete the report. You can also include a comment.