Analyzes for hormones

Adrenaline and norepinephrine in the blood

Adrenaline is the hormone of the adrenal medulla. From the adrenal medulla it enters the bloodstream and acts on the cells of distant organs. Its content in the blood depends on the tone of the sympathetic system. In hepatocytes, epinephrine stimulates the breakdown of glycogen and thereby increases the glucose level in the blood. In adipose tissue adrenaline activates lipase and the process of cleavage of TG.

Functional state of sympathoadrenal system

Like the posterior lobe of the pituitary gland, the adrenal medulla is a derivative of the nerve tissue. It can be considered as a specialized sympathetic ganglion.

Pyridinoline and deoxypyridinoline in the urine

The stability of the collagen matrix is provided by intermolecular irreversible bonds formed between some amino acids entering the polypeptide chain of collagen. Due to the presence of the pyridine ring, the cross bonds are called pyridinoline (Pid) and deoxypyridinoline (Dpid).

Cross-linked N-telopeptide in urine

The cross-linked N-telopeptide of type I bone collagen serves as a marker of osteoclast activity and is used in clinical practice to assess the level of bone resorption, as well as the effectiveness of osteoporosis treatment.

C-terminal telopeptide in blood

Collagen type I accounts for more than 90% of the organic matrix of bone. As a result of permanent remodeling of bone tissue collagen type I is destroyed, while its fragments enter the blood.

Osteocalcin in the blood

Osteocalcin is a vitamin K-dependent non-collagen protein of bone tissue (vitamin K is necessary for the synthesis of active calcium-binding protein centers) - is localized predominantly in the extracellular matrix of the bone and accounts for 25% of the non-collagen matrix.

Markers of bone formation and resorption

Bone tissue forms a dynamic "depot" of calcium, phosphorus, magnesium and other compounds necessary to maintain homeostasis in mineral metabolism. Bone consists of three components: cells, organic matrix and mineral substances. The share of cells accounts for only 3% of the volume of bone tissue.

Calcitriol in the blood

Vitamin D3 (cholecalciferol) is formed in the skin of 7-dehydrocholesterol under the influence of sunlight or enters the body with food. The synthesized and received vitamin D3 is transported by blood to the liver, where in mitochondria it is converted to 25-hydroxyvitamin [25 (OH) D3].

Blood parathyroid hormone

Parathyroid hormone - a polypeptide consisting of 84 amino acid residues, is formed and secreted by parathyroid glands in the form of high-molecular prohormone. Progormone after exiting the cells undergoes proteolysis with the formation of parathyroid hormone.

Natriuretic peptides in the blood

Sodium uretic peptides are important in regulating the volume of sodium and water. The first was the atrial natriuretic peptide (ANP), or the atrial natriuretic peptide type A.

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