Alisa's syndrome in Wonderland

At first glance, the fabulous term "Alice's syndrome in Wonderland" does not mean such a harmless disease, which, fortunately, is extremely rare. The disease is a neurological disorder, in which there is a distortion of reality. The world is perceived by the patient as if in a fairy tale: the surrounding objects take unnaturally large or small dimensions, distances and boundaries are distorted. The visual image becomes like a "crooked mirror".

What causes this syndrome? Can it be cured?

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Epidemiology

Alisa's syndrome in the wonderland is diagnosed mainly in childhood - in the period of 5-13 years. However, the development of the disease is also possible in adult patients - after 20-25 years.

The disease is not recognized as chronic. In most cases, the syndrome is transient, manifesting itself temporarily and sporadically. Nevertheless, there are several cases where the signs of the disease have not left patients for many years.

Alisa's syndrome in Wonderland is considered a very rare disorder. For example, according to American statistics, at the moment they are sick no more than three hundred Americans.

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Causes of the alice's syndrome in Wonderland

Scientists have identified a number of reasons that can lead to the appearance of Alice's syndrome in Wonderland:

• frequent migraine attacks, with prolonged and debilitating pain in the head;
• schizophrenia - a violation of the psyche, accompanied by mental disorders, hallucinations, distortion of perception of the surrounding space;
• infectious mononucleosis, which affects various parts of the brain;
• epileptic seizures accompanied by hallucinogenic conditions;
• malignant neoplasms in the brain.

When diagnosing Alice's syndrome, it is also necessary to take into account such risk factors as the use of psychotropic and hallucinogenic drugs, substance abuse, drug addiction, smoking of anasha, cannabis, marijuana, and frequent and deep stressful situations, excessive susceptibility and susceptibility of the person, lability of the nervous system.

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Pathogenesis

The essence of Alice's syndrome in the land of miracles has not been fully clarified to the present day. It is commonly believed that the disease is preceded by various exogenous factors that can be divided into two groups:

• organic influences on the work of the brain - the consequences of injuries, poisoning, infectious diseases, radiation, etc .;
• psychoemotional effects - conflicts (both with others and with oneself), stresses, adverse influence of the society.

Sometimes it is possible to influence several factors at once. In this case, the main one is the one that determines the onset of the disease and its dynamic development.

Currently, the mechanism of the development of the pathological process is under consideration, since Alisa's syndrome in Wonderland is considered a rare pathology.

Symptoms of the alice's syndrome in Wonderland

Alisa's syndrome in Wonderland occurs in the form of seizures, which can last for less than one minute, and several days (according to some descriptions - even about a month).

The first signs of an attack of Alisa's syndrome:

• Surrounding objects suddenly increase or decrease significantly in size;
• the distance between objects decreases or increases;
• the proportions of objects vary.

Practically in all cases, the patient perceives the visible picture in real terms, that is, identifying it with real time. At the same time, a person may lose orientation in space, be greatly frightened (up to the development of a phobia).

Externally, the attack is accompanied by such symptoms:

• tachycardia;
• frequent, agitated breathing;
• signs of an increasing panic attack.

In some patients, the first sign of an attack of Alisa's syndrome is headache (migraine-like headache).

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Stages

The attack of Alice's syndrome in the wonderland can proceed in different ways: it means the duration and clinical manifestations of the attack. In connection with such differences, it is customary to distinguish three fundamental stages:

• the initial stage of an attack - can begin with a headache or general anxiety, with a gradual or rapid increase in symptoms;
• the main stage of the attack is the most active phase of manifestation of clinical symptoms;
• The final stage is the phase, when the manifestations of an attack weaken.

During the final stage, patients can note the appearance of sudden fatigue, apathy, indifference and drowsiness.

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Forms

There are two clinical types of Alice's syndrome in Wonderland:

• Macroscopia (giant hallucinations) - in this condition, the patient feels that the surrounding objects suddenly and greatly increased in size.
• Micropsia (dwarf hallucinations) - the patient perceives the surrounding objects in opposition to the macropsia, that is, too small.

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Complications and consequences

The consequences of Alice's syndrome in Wonderland can be different, but they can all be divided into two types - these are psychological and social consequences.

The psychological consequences are that the patient unconsciously expects and is afraid of a repeat of the attack. In this regard, he closes in himself, avoids communication, tries not to leave the house and not to visit the crowded places.

The repeated attacks of Alice's syndrome in Wonderland can lead to the development of prolonged depression, a weakening of concentration, and even a sense of despair. Complicated and prolonged seizures can lead to loss of ability to work, to personal and social problems. Often the patient becomes the object of ridicule and misunderstanding from others, and even close people.

Against the background of a constant sluggish depression and a depressed state, various somatic diseases can develop. The cardiovascular, nervous and digestive system suffers more.

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Diagnostics of the alice's syndrome in Wonderland

The diagnosis of "Alice's syndrome in Wonderland" is based on information obtained from the patient himself. For example, the doctor will find out from the patient the following questions:

• When did the first attack of the syndrome?
• How long did it last?
• What exactly did the patient feel during the attack?
• With what does the patient connect the beginning of the attack?
• Were there similar seizures? If so, how often?

Since Alice's syndrome in Wonderland is quite a specific condition, laboratory and instrumental diagnostics are often not used, due to their low information content.

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Differential diagnosis

Nevertheless, for differential diagnosis, the use of CT, electroencephalography, spinal puncture with fluid analysis is possible.

In addition, the doctor conducts a neurological examination, which is especially informative at the time of the attack of Alisa's syndrome. Symptoms such as tachycardia, increased blood pressure, frequent respiratory movements, general anxiety can be detected. If necessary, counseling psychoneurologist, narcologist, therapist is appointed.

Differential diagnosis can be conducted with such diseases and conditions:

• panic attacks;
• narcotic, alcoholic or other psychotropic intoxication;
• febrile state with delusional syndrome.

Treatment of the alice's syndrome in Wonderland

Treatment for Alisa in the Wonderland is administered individually. If the doctor can determine the cause of the disease, then the therapeutic manipulations are directed to eliminate this cause, as well as to alleviate the painful symptoms. So, with epilepsy prescribe anticonvulsants and relaxants, with migraines - analgesics and soothing agents, etc.

To prolong the period between attacks, the patient is recommended to take a course with a psychotherapist or a psychologist. Such activities reduce the severity of fears, derive from depressive conditions.

A special place in the rehabilitation of patients with Alice's syndrome in Wonderland is the support of the family and relatives. It is undesirable to leave a sick person (especially a child) alone with himself.

A good therapeutic effect can have hypnosis sessions and cognitive-behavioral therapy.

Medications

Medications are prescribed to reduce the severity of symptoms during the seizures in Alice's syndrome in Wonderland. The doctor can apply the following drugs:

• soothing agents - Persen, Tenoten, valerian extract;
• antidepressants - Amitriptyline, Prozac;
• benzodiazepines - Clobazam, Chlordiazepoxide;
• nootropic drugs - Glycine, Pyrithinol, Pyracetam.

	Dosing and Administration	Side effects	Special instructions
Persen	Take inside 2-3 tablets up to 3 times a day. The maximum daily dosage is 12 tablets.	Possible allergies, constipation, the phenomenon of bronchospasm.	Persen is not recommended to take long, more than 2 months.

	Dosing and Administration	Side effects	Special instructions
Prozac	The drug is taken from 20 to 60 mg / day, regardless of food intake.	Dyspepsia, nervousness, ataxia, decreased libido, frequent urination, allergies are possible.	If the patient is diagnosed with epilepsy, then Prozac is prescribed with extreme caution.

	Dosing and Administration	Side effects	Special instructions
Clobazam	Take 5 to 15 mg per day, with a possible gradual increase in dosage to 50 mg per day.	May cause drowsiness, allergies, ataxia.	Clobazam can cause drug dependence, so taking the drug for more than 4 consecutive weeks is not recommended.

	Dosing and Administration	Side effects	Special instructions
Pyracetam	Take from 30 to 160 mg per kg of weight per day. Dosage is divided into 2-4 reception. The course of therapy can be 1.5-2 months.	Dyspepsia, irritability, drowsiness, and increased libido are possible.	During treatment it is necessary to observe the functional parameters of the urinary system.

	Dosing and Administration	Side effects	Special instructions
Glycine	Take under the tongue of 1 tablet up to 3 times a day, for 2 or 4 weeks.	It is rare to develop allergies.	Glycine does not accumulate in the body, it is well tolerated, it does not cause dependence. You can treat with glycine 4-6 times a year.

Prevention

Specific measures for the prevention of Alice's syndrome in Wonderland do not exist, because the disease is considered rare and has so far been little studied. However, general advice on preventing such conditions, doctors can provide.

1. Stress-resistance, the ability to withstand stress - if you develop such qualities in yourself, then diseases such as Alice's syndrome in Wonderland, and other neuroses and phobias, will bypass.
2. Full rest, walks, active games and sports have a general positive effect on health, both physical and mental.
3. Yoga classes, meditation are considered to be excellent ways to relax, strengthen the nervous system, relieve tension. The only condition is to practice meditation and practice yoga regularly.
4. A healthy lifestyle is an integral part of the prevention of Alice's syndrome, because alcohol, drugs and psychotropic drugs can easily provoke the development of the disease.
5. Proper nutrition should include the exclusion of products that can provoke migraine attacks. Such products include coffee, strong tea, spirits, chocolate, cocoa.

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Forecast

Alisa's syndrome in Wonderland is still a little studied disease. And there is no specific treatment scheme for this pathology. With a competent approach and correctly selected medicines, it is possible to reduce the duration and the number of seizures. This allows you to expand the communication of the patient, to facilitate his social adaptation and even restore work capacity.

Qualitatively conducted psychotherapy can relieve the patient of phobias that have arisen, which will allow him to return to the normal lifestyle of a healthy person.

Despite the ongoing treatment, it is almost impossible to completely eliminate Alice's syndrome in a wonderland.

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