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Treatment of toxoplasmosis
Last reviewed: 20.11.2021
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A complex treatment of toxoplasmosis with the inclusion of etiotropic, immunostimulating, pathogenetic and symptomatic agents is necessary.
As an etiotropic treatment, chloride is used in combination with sulfanilamide preparations (sulfadimezine, sulfapyridazine, bactrim, etc.). There are various treatment regimens. Etiotropic treatment is often performed in cycles of 5-10 days with intermissions between them 7-10 days in combination with probiotics (acipol, etc.). Usually spend 3 cycles, which is 1 course. Medicinal products are given in an age-appropriate dose of 4 doses. To prevent side effects of chloridine, multivitamins and folic acid are prescribed. With contraindications to the use of chloridine (disease of the hematopoietic organs, kidneys, etc.), treatment is carried out with delagil, trichopolum, aminoquinol.
In severe forms of acute toxoplasmosis, the appointment of glucocorticoids is calculated from the calculation of 1.5-2 mg / kg for prednisolone for 10-14 days. Especially shown are glucocorticoids with congenital toxoplasmosis with encephalitis, meningoencephalitis, liver, eye and other organs.
With chronic forms of toxoplasmosis etiotropic therapy is ineffective, it is advisable to conduct it only with parasitemia, i.e. In the initial stage of exacerbation of the disease. The main attention in these cases should be given to the strengthening of nonspecific factors of resistance and normalization of body functions. Necessarily appoint multivitamins (C, B1, B2, P, nicotinic acid, etc.). Use blood products (immunoglobulins, albumin), stimulators of hematopoiesis (pentoxil, aloe, etc.). Assign desensitizing [clemastine, chloropyramine (suprastin)], sedatives, choleretic and other medications.
Forecast
The majority of infected people develop a latent infection with full clinical well-being. After the transferred manifest forms of acquired toxoplasmosis, irreversible changes in the central nervous system, eyes, internal organs, leading to disability, can remain. In children of early age, generalized forms of the disease can end up lethal. With congenital toxoplasmosis, the prognosis is often unfavorable. The disease often ends in death or leads to severe irreversible consequences.