Benign skin lymphoplasia: causes, symptoms, diagnosis, treatment
Last reviewed: 23.04.2024
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Benign skin lymphoplasia (synonyms: benign Bifurstedt lymphadenosis, lymphocytes, lymphoid skin hyperplasia, etc.).
Causes and pathogenesis of benign skin lymphoplasia. Provoking factors are insect bites, inhalation, trauma, shingles, etc. Perhaps the development of benign lymphoplasia develops in patients with scabies, which is called post-bacterial lymphoplasia of the skin. It is believed that the onset of the disease is associated with reactive hyperplasia of embryonic lymphoid tissue.
In the pathogenesis of the disease, an important role is played by the immune system, since infiltration with macrochains and lymphoid cells is noted in the lesion focus.
Symptoms of benign skin lymphoplasia. Lymphoplasia benign can develop at any age, both in men and in women.
Symptoms of the disease is characterized by the appearance of nodules, plaques or infiltrative-tumor elements, located mainly on the skin of the face, mammary glands, genitals, axillary pits. Nodules are hemispherical, rounded. Or oval outlines with clear boundaries, a dense elastic consistency, smooth or scaly covered surface of a cyanotic-pink color. The number of nodules varies from single to multiple, which is especially typical of post-scabious lymphoplasia. Often there is a spontaneous regression of the rash, in place of which hyperpigmented spots may disappear, gradually disappearing. In the tumor form of the tumor have a different value - from beans to cherries and more, a dense elastic consistency. The color of the tumors is pink-red at first, then acquires a bluish-pink hue. Tumors, as a rule, are embedded in the skin and subcutaneous tissue, are closely welded to the skin, when palpated they are mobile in relation to the underlying tissues. Distinguish between solitary and disseminated variants of the location of nodes and nodules.
Infiltrative tumorous formations of red-brown color have a rounded shape with sharp boundaries and a testic consistency.
Sometimes itching is possible. One patient may have different clinical forms of benign skin lymphoplasia.
Histopathology. Histologically, a dense large-focal infiltrate is noted in the dermis, which is separated from the epidermis by a narrow strip of unaltered collagen. The infiltrate consists of lymphocytes, histiocytes, plasma cells, eosinophilic granulocytes. In structure, infiltrates resemble primary and secondary follicles of the lymph nodes. Sometimes there is a granulomatous structure.
Differential diagnosis. Benign skin lymphoplasia should be differentiated from eosinophilic face granuloma, limited lymphangioma, sarcoidosis, trichoepithelioma, lymphosarcoma, discoid lupus erythematosus.
Treatment of benign skin lymphoplasia. Assign non-steroidal anti-inflammatory drugs (indomethacin, volta-ren) and corticosteroids (obkalyvanie and under the occlusive dressing). A good effect is observed when using X-ray therapy and antibiotics.
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