Chlorhydropenic (chloroprivine, hypochloraemic) coma

Chlorohydropenic (chloroprivine, hypochloraemic) coma is a coma that develops as a result of severe water-electrolyte balance disturbances with significant and prolonged loss of water and salts, primarily chlorine and sodium.

Causes of hypochloraemic coma

1. Persistent vomiting of any origin (decompensated stenosis of the pyloric ulcer or cancer etiology, duodenal obstruction, Zollinger-Elisson syndrome-gastrin-producing pancreatic tumor in combination with the non-healing and often exacerbated ulcer of the gastro-duodenal region, brain tumors, uncontrollable vomiting of pregnant women, intestinal obstruction, poisoning, cholelithiasis, acute pancreatitis, kidney disease).
2. Indomitable diarrhea of any etiology (toxicinfection, enteritis, Crohn's disease, sprue, severe degree of gluten enteropathy, ulcerative colitis, cholera and other intestinal infections, irrational use of laxatives).
3. Excessive diuresis with excessive use of diuretics.
4. Repeated gastric lavage, frequent pleural punctures, abdominal paracentesis with the removal of a large amount of fluid.

Causes of hypochloraemic coma

Symptoms of hypochloraemic coma

In most patients, coma develops gradually, most often after a previous prolonged vomiting, diarrhea, and abundant diuresis (depending on the underlying disease). In prekomatoznom state of concern severe weakness, dizziness, severe thirst, dry mouth, palpitations, muscle twitching, often cramps in the calf muscles.

Symptoms of hypochloraemic coma

Diagnosis of hypochloraemic coma

1. A general blood test: an increase in the content of red blood cells and hemoglobin (blood thickening), a hematocrit up to 55% or more, leukocytosis, an increase in ESR.
2. The general analysis of urine: decrease in quantity and relative density of urine - there is a proteinuria, the cylinderuria is possible.

Diagnosis of hypochloraemic coma