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Treatment for typhoid fever

Alexey Kryvenko, Medical Reviewer, Editor
Last reviewed: 04.07.2025

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In case of diarrhea syndrome, the diet is based on the same principles as in case of other intestinal infections. In case of toxicosis with exsicosis, oral rehydration is performed, and in case of severe dehydration (II-III degree) - rehydration infusion therapy in combination with detoxification (1.5% reamberin solution, isotonic, electrolyte solution with antihypoxant activity) and syndrome-based treatment.

Of the etiotropic therapy agents, levomycetin or levomycetin sodium succinate are used. They have a pronounced bacteriostatic effect on typhoid-paratyphoid bacteria. Levomycetin is prescribed orally in a single dose of 0.01-0.02 g / kg for young children and 0.15-0.25 g / kg for children of preschool and school age 4 times a day. Levomycetin is used throughout the febrile period and for another 7-10 days after the normal body temperature is established. If levomycetin is ineffective, ampicillin, bactrim, lidaprim can be used. Ampicillin turned out to be the drug of choice, since when it is used in the treatment of typhoid fever, as a rule, there are no relapses of the disease. Probiotics (Acipol, etc.) are prescribed simultaneously with antibiotics.