Medical expert of the article
New publications
Treatment of toxoplasmosis
Last reviewed: 04.07.2025
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Comprehensive treatment of toxoplasmosis is necessary, including etiotropic, immunostimulating, pathogenetic and symptomatic agents.
Chloridin is used as an etiotropic treatment in combination with sulfonamide drugs (sulfadimezine, sulfapyridazine, bactrim, etc.). There are various treatment regimens. Etiotropic treatment is often carried out in cycles of 5-10 days with breaks between them of 7-10 days in combination with probiotics (atsipol, etc.). Usually 3 cycles are carried out, which is 1 course. Medicines are given in an age-appropriate dose in 4 doses. To prevent the side effects of chloridin, multivitamins and folic acid are prescribed. In case of contraindications to the use of chloridin (diseases of the hematopoietic organs, kidneys, etc.), treatment is carried out with delagyl, trichopolum, aminoquinol.
In severe forms of acute toxoplasmosis, glucocorticoids are indicated at a rate of 1.5-2 mg/kg of prednisolone for 10-14 days. Glucocorticoids are especially indicated in congenital toxoplasmosis with encephalitis, meningoencephalitis, damage to the liver, eyes and other organs.
In chronic forms of toxoplasmosis, etiotropic therapy is ineffective and should only be used in the case of parasitemia, i.e., in the initial stage of exacerbation of the disease. In these cases, the main focus should be on enhancing non-specific resistance factors and normalizing body functions. Multivitamins (C, B1, B2, P, nicotinic acid, etc.) are mandatory. Blood products (immunoglobulins, albumin), hematopoiesis stimulants (pentoxyl, aloe, etc.) are used. Desensitizing [clemastine, chloropyramine (suprastin)], sedatives, choleretic and other medications are prescribed.
Forecast
Most infected people develop a latent infection with complete clinical well-being. After suffering manifest forms of acquired toxoplasmosis, irreversible changes in the central nervous system, eyes, internal organs may remain, leading to disability. In young children, generalized forms of the disease can end fatally. In congenital toxoplasmosis, the prognosis is often unfavorable. The disease often ends in death or leads to severe irreversible consequences.