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Squamous cell cancer of the conjunctiva: causes, symptoms, diagnosis, treatment

 
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Last reviewed: 04.07.2025
 
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Squamous cell carcinoma of the conjunctiva is a rare, slow-growing, low-grade tumor that may arise independently or from preexisting CIN. It is most common in patients with xeroderma pigmentosum and AIDS.

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Symptoms of squamous cell carcinoma of the conjunctiva

Squamous cell carcinoma of the conjunctiva usually presents in old age, as does CRI. The fleshy, pink, papillomatous or gelatinous mass is often associated with a feeding vessel, which may occasionally be covered with keratin plaques. The tumor is most often located perilimbally and rarely in the fornix or palpebral conjunctiva. Limbal tumors may involve the adjacent cornea, but extension into the sclera is rare.

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Treatment of squamous cell carcinoma of the conjunctiva

  • Surgical excision and additional cryotherapy.
  • Local chemotherapy with mitomycin C or 5-fluorouracil may be indicated both in relapses and in primary treatment at the initial stage.
  • Enucleation in cases of intraocular spread.
  • Evisceration in advanced cases involving the orbit.

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