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Phacogenic open-angle glaucoma: causes, symptoms, diagnosis, treatment

 
, medical expert
Last reviewed: 08.07.2025
 
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Phacogenic open-angle glaucoma includes three different diagnoses with similar clinical symptoms. Phacolytic glaucoma, glaucoma of the lens masses, and phacogenic uveitis (FGU) develop with an intraocular inflammatory process, an abnormal lens, and increased intraocular pressure, but hypotension usually develops later. Differentiation of these three pathologies requires careful examination and understanding of the mechanisms that determine the development of each disease.

Clinical manifestations of phacogenic open-angle glaucomas

Glaucoma of the lens masses

Phacolytic glaucoma

Phacogenic open-angle glaucoma

Mechanism

The lens substance blocks the TS

VMB of the lens blocks the TS

Immune tolerance disorder

Intraocular pressure

Increased

Increased

Decreased or increased

Gonioscopy

Open corner

Open corner

Open corner

Condition of the lens

Rupture of the lens capsule with release of lens masses

Mature or hypermature cataract

Rupture of the lens capsule; expulsion of large fragments of the lens

Treatment

Antiglaucoma treatment, glucocorticoids, surgical removal of lens masses

Antiglaucoma treatment, local glucocorticoids, cataract extraction

Antiglaucoma treatment, local glucocorticoids, removal of lens fragments

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