The most severe type of headache that can affect people of both sexes and almost all ages is cluster headache. The pain syndrome that occurs suddenly, against the background of general well-being, is characterized by pain of such intensity that people are ready to say goodbye to life, just to get rid of the painful sensations. Until now, the true causes that give rise to this type of pathology have not been identified, but there are a number of assumptions that allow, if not to rid a person of pain forever, then at least to reduce the degree of its manifestation.