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Medullary sponge kidney.
Last reviewed: 04.07.2025

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Causes of a medullary spongy kidney.
Medullary spongy kidney is considered a congenital disease. The anomaly is formed at relatively early stages of ontogenesis, since histological examination reveals areas of embryonic renal tissue.
The significance of hereditary factors in the development of medullary sponge kidney has not been established. Cases of combination of medullary sponge kidney with developmental anomalies of other organs, including hereditary syndromes (Ehlers-Danlos, Marfan) as well as congenital heart defects and Caroli disease have been described.
Symptoms of a medullary spongy kidney.
There are no symptoms of medullary sponge kidney. Common complications of medullary sponge kidney are nephrolithiasis and urinary tract infections.
Diagnostics of a medullary spongy kidney.
Laboratory diagnostics of medullary sponge kidney
Most patients with medullary sponge kidney have microhematuria; episodes of macrohematuria are possible.
Instrumental diagnostics of medullary sponge kidney
The method of choice for diagnosing medullary spongy kidney is intravenous pyelography. When contrasted, the dilated sections of the collecting ducts acquire a characteristic "bunch of grapes" or "bouquet of flowers" appearance.
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Treatment of a medullary spongy kidney.
Treatment of medullary sponge kidney has not been developed. In case of irreversible deterioration of kidney function, methods of renal replacement therapy are used.
Forecast
The prognosis of patients with medullary sponge kidney depends on the frequency of episodes of macrohematuria, urinary tract infections, and the severity of nephrolithiasis. With adequate prevention and treatment of nephrolithiasis and urinary tract infections, medullary sponge kidney is a relatively benign condition.