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Malignant fibrous histiocytoma of bone
Last reviewed: 07.07.2025

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Malignant fibrous histiocytoma of bone is a high-grade tumor with an unknown incidence. The tumor's main constituents are histiocyte-like cells and spindle-shaped fibroblasts, which are present in varying proportions.
ICD-10 code
- C40. Malignant neoplasm of bone and articular cartilage of extremities.
- C41. Malignant neoplasm of bone and articular cartilage of other and unspecified sites.
Symptoms
The clinical picture of MFH is similar to that of osgeogenic sarcoma. Radiological differential diagnostics has a certain meaning in the presence of the lytic form of bone tumor, since such a picture cannot be present in malignant fibrous histiocytoma.