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Chondrosarcoma
Last reviewed: 20.11.2021
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Chondrosarcoma is a malignant tumor of cartilaginous tissue. For this neoplasm is characterized by the presence of a cartilaginous tissue without signs of formation of a malignant osteoid.
ICD-10 code
- C40. Malignant neoplasm of bones and articular cartilage of extremities.
- C41. Malignant neoplasm of bones and articular cartilages of other and unspecified sites.
Chondrosarcoma occurs mainly in individuals older than 40 years. In children and adolescents, these diseases are rare.
What causes chondrosarcoma?
Chondrosarcoma can develop against the backdrop of osteochondrosis, less often the enchondrosis, as well as non-lignified osteochondral exostoses with hereditary exostosis disease.
How is chondrosarcoma manifested?
The clinical picture does not have distinctive features in comparison with other malignant tumors of bones. Chondrosarcoma requires careful differential diagnosis with osteogenic sarcoma with a cartilage component by histological examination of the tumor. In contrast to osteogenic sarcoma, it occurs later hematogenous metastasis. At the same time, the prognosis of the disease with pulmonary metastases of this tumor is very serious.
How is chondrosarcoma treated?
The principles of diagnosis and treatment plan for chondrosarcoma are constructed in a similar way to those for osteogenic sarcoma. The rejection of low-grade chemotherapy in children and adolescents is a mistake.