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Chondrosarcoma
Last reviewed: 05.07.2025
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Chondrosarcoma is a malignant tumor of cartilaginous tissue. This neoplasm is characterized by the presence of cartilaginous tissue without signs of malignant osteoid formation.
ICD-10 code
- C40. Malignant neoplasm of bone and articular cartilage of extremities.
- C41. Malignant neoplasm of bone and articular cartilage of other and unspecified sites.
Chondrosarcoma occurs mainly in people over 40 years of age. In children and adolescents, these diseases are rare.
What causes chondrosarcoma?
Chondrosarcoma can develop against the background of osteochondromas, less often enchondromas, as well as non-malignant osteochondral exostoses in hereditary exostosis disease.
How does chondrosarcoma manifest itself?
The clinical picture does not have any distinctive features compared to other malignant bone tumors. Chondrosarcoma requires careful differential diagnostics with osteogenic sarcoma with a cartilaginous component using histological examination of the tumor. Unlike osteogenic sarcoma, it has later hematogenous metastasis. At the same time, the prognosis of the disease with pulmonary metastases of this tumor is very serious.
How is chondrosarcoma treated?
The principles of diagnosis and treatment plan for chondrosarcoma are similar to those for osteogenic sarcoma. Refusal of chemotherapy for low-differentiated sarcoma in children and adolescents is a mistake.