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Jessner-Kanof lymphocytic infiltration: causes, symptoms, diagnosis, treatment
Last reviewed: 07.07.2025
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Jessner-Kanof lymphocytic infiltration was first described in 1953 by M. Jessner, NB Kanof.
The causes and pathogenesis of dermatosis are not fully understood. Some dermatologists consider it a type of benign lymphoplasia of the skin, others - as a variant of chronic erythematosis. Most researchers consider it an independent disease.
Symptoms. The disease often occurs in men aged 20-60 years. It appears as flat plaques of fairly large size (from a child's palm to an adult's palm), clear boundaries, ring-shaped outlines and a bluish-pink color. The surface of the plaques in most patients is smooth, but sometimes slight peeling is possible. Plaques are usually single, located on the face (zygomatic arches and cheeks), neck, but can be on the trunk and limbs. The dermatosis is characterized by a long, persistent and wave-like course, but at the same time tends to spontaneous resolution. Papular rashes are sometimes noted.
Histopathology: The histological epidermis is intact, the dermis contains periglandular and perivascular lymphocyte clusters, sometimes with admixture of histiocytes, eosinophils, plasma cells and macrophages.
Differential diagnosis. The disease should be distinguished from drug-induced toxicoderma, sarcoidosis, syphilis, and lupus erythematosus.
Treatment of Jessner-Kapof lymphocytic infiltration. Prescribe antimalarial (delagyl, plaquenil) or nonsteroidal anti-inflammatory (indomethacin, voltaren) drugs, corticosteroid ointments, injections of foci with cynologist or diprospan.
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