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Lymphocytic infiltration Jessner-Kanoff: causes, symptoms, diagnosis, treatment
Last reviewed: 23.04.2024
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Infiltration of the lymphocyte of Jessner-Kanof was first described in 1953 by M. Jessner, NB Kanof.
The causes and pathogenesis of dermatosis are not fully understood. Some dermatologists see it as a kind of benign skin lymphoplasia, others - as a variant of chronic erythematosis. Most researchers consider it an independent disease.
Symptoms. The disease is common in men aged 20-60 years. It appears in the form of flat plaques, which are quite large (from the palm of a child to the palm of an adult), clear boundaries, ring-shaped outlines and a cyanotic-pink coloration. The surface of the plaques in most patients is smooth, but sometimes a little peeling. Plaques, as a rule, are single, located on the face (the area of the zygomatic arches and cheeks), neck, but can be on the trunk and extremities. Dermatosis is characterized by a long, stubborn and undulating course, but at the same time prone to spontaneous resolution. Sometimes there are papular rashes.
Histopathology. Histological epidermis is intact, in the dermis there are perigendulary and perivascular clusters of lymphocytes, sometimes with an admixture of histiocytes, eosinophils, plasma cells and macrophages.
Differential diagnosis. The disease should be distinguished from drug toxicodermia, sarcoidosis, syphilis, lupus erythematosus.
Treatment of infiltration of lymphocytic Jessner-Kapof. Assign antimalarial (delagil, plakvenil) or non-steroidal anti-inflammatory (indomethacin, voltaren) drugs, corticosteroid ointments, chopping foci by a cenoman or diprospan.
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