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Gastroenterologist

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Erosion of the stomach and duodenum: causes

Alexey Portnov, medical expert
Last reviewed: 23.04.2024

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The main causes of erosions of the stomach and duodenum are:

infection of the mucous membrane with Helicobacteria;
psychoemotional stressful situations (G. Selye's adaptation disease with erosive-ulcerative lesions of the gastroduodenal system);
the use of rough, spicy, hot food and alcohol;
the intake of salicylates and other NSAIDs, as well as glycocorticoids, reserpine, digitalis, and certain antibiotics;
stasis in the portal vein with cirrhosis of the liver or thrombosis of the portal vein (erosion in the esophagus and stomach is formed, chronic erosion is more often observed with alcoholic, and acute - with viral cirrhosis of the liver);
hernia of the esophageal opening of the diaphragm (erosions develop in the area of the hernial sac and are very often complicated by bleeding);
chronic pancreatitis;
chronic hepatic insufficiency;
diabetic ketoacidosis (pronounced degree);
diseases of the cardiovascular system and respiratory organs, leading to hypoxemia of organs and tissues, including the mucosa of the gastroduodenal region;
influence on the mucous membrane of occupational hazards (salts of heavy metals, acids, alkalis, etc.);
duodenogastric reflux and casting of bile into the stomach (detergents influence bile on the gastric mucosa);
malignant or systemic process in the mucous membrane of the stomach (cancer, lymphoma, etc.).

trusted-source [1], [2], [3]