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Duodenal dyskinesia - Treatment
Last reviewed: 06.07.2025
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Treatment of disorders of the motor-evacuation function of the duodenum should be comprehensive and strictly individual, with the aim of eliminating the exacerbation of the underlying disease and restoring its function. The diet largely depends on the nature of the underlying and concomitant diseases. In cases where motor disorders are accompanied by a violation of the drainage function of the intestine, frequent fractional meals are necessary (5-6 times a day, in small portions). Food should be easily digestible, rich in vitamins, and contain little fiber. In case of severe symptoms of duodenal obstruction, repeated vomiting, parenteral nutrition is effective. One of the effective means of treating duodenostasis is duodenal lavage: using a duodenal probe, 300-350 ml of mineral water is successively poured into the intestine in small portions once every 3-4 days.
In hypermotor dyskinesias, it is justified to prescribe peripheral antispasmodics, anticholinergics that suppress the motor activity of the duodenum. In particular, intravenous administration of gastrocepin has an inhibitory effect on intestinal peristalsis. Prostin E2 also has a similar effect on the motor function of the intestine. Intravenous administration of dalargin, a synthetic analogue of enkephalins, has a peculiar, initially short-term stimulating and then long-term suppressive effect on the motor function of the duodenum. In hypomotor dyskinesias, proserin, metoclopramide and its analogues (reglan, cerucal) are indicated, which stimulate motor activity, increase the rate of evacuation of contents through the duodenum. Another drug from the orthopramide group, eglonil (sulpiride), has a slightly different - normalizing - effect, which can be taken for any form of duodenal dyskinesia. Eglonil also has neuroleptic properties, so it is effective in neurotic disorders that often accompany duodenostasis. Surgical intervention is recommended only if all conservative therapy methods have failed.
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