For the first time in 1951, E. J. Gardner, and 2 years later, E. J. Gardner and R. C. Richards described a peculiar disease characterized by multiple cutaneous and subcutaneous lesions occurring simultaneously with tumor lesions of the bones and tumors of soft tissues. Currently, this disease, combining polyposis of the gastrointestinal tract, multiple osteomas and osteofibromas, tumors of soft tissues, is called Gardner's syndrome.