Diseases of children (pediatrics)

Craniosynostosis

Craniosynostosis - premature overgrowing of one or more seams of the skull, leading to the formation of a characteristic deformation. Craniostenosis is a nonspecific brain damage that occurs as a result of insufficient expansion of the cranial cavity during the most active growth of the brain.

Stealth

Steering is a severe deformation, the main feature of which is a persistent deviation of the hand toward the missing or underdeveloped forearm bone: in the absence of the radius, the manus vara, in the absence of the ulnar, is the elbow of the manus valga.

Perinatal encephalopathy

Perinatal encephalopathy is a pathology that develops in a fetus or a newborn due to insufficient supply of oxygen to the brain, is one of the most common lesions of the neonatal nervous system. Depending on how long the process of oxygen starvation was, the brain can develop local edema up to necrosis.

Analysis of anticonvulsants in children with symptomatic epilepsy

Epilepsy has been and remains an extremely important medical and socially significant problem of pediatric neurology. According to some authors, the average annual incidence of epilepsy in the economically developed countries of the world is 17.3 cases per 100 thousand people per year.

Diastolic function of the left ventricle in children with secondary cardiomyopathy

The structure of cardiac pathology has undergone significant changes in the last decades of the last century. In Ukraine there is a persistent tendency to increase the cardiovascular morbidity of non-rheumatic nature, including secondary cardiomyopathies (CMS). Their prevalence increased from 15.6% in 1994 to 27.79% in 2004.

The use of melatonin in cancer practice

Melatonin, a hormone of the pineal gland, has powerful antioxidant, immunomodulating and detoxifying effects. Studies of recent decades indicate that melatonin is inherent in numerous oncostatic properties.

Treatment of dry cough in a child

In order to properly cure cough, you need to know exactly what it provoked. If there is a dry cough in the child, the treatment should be carried out using various means and procedures that will help him to take a productive form, under the supervision of a doctor.

Diseases of Thea-Sachs and Sandhoff

Diseases of Thea-Sachs and Sandhoff are sphingolipidoses, which are caused by a deficiency of hexosaminidase, leading to severe neurologic manifestations and early death of the child.

Periodic syndrome associated with TNF receptors (TNF)

Family Irish fever (a periodic syndrome associated with receptors of tumor necrosis factor (TNF)) is a hereditary disease manifested by recurrent episodes of fever and migrating myalgia with painful erythema of the skin above it. The level of TNF receptor type I is low. Treatment is carried out by glucocorticosteroids and etanercept.

Disruption of the metabolism of pyruvate

The inability to metabolize pyruvate leads to lactic acidosis and various CNS disorders. Pyruvate is an important substrate for carbohydrate metabolism. Pyruvate dehydrogenase is a multienzyme complex responsible for the formation of acetylCoA from pyruvate for the Krebs cycle. Deficiency of this enzyme leads to an increase in the level of pyruvate and therefore an increase in the level of lactic acid.

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