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The causes of increase and decrease in T-lymphocytes-suppressors (CD8)
Alexey Portnov, medical expert
Last reviewed: 19.10.2021
Last reviewed: 19.10.2021
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Diseases and conditions that lead to a change in the number of CD8-lymphocytes in the blood
Increase in the
- Autoimmune diseases
- Systemic lupus erythematosus
- Sjogren's syndrome, Felty
- Rheumatoid arthritis
- Systemic sclerosis, collagenoses
- Dermatomyositis, polymyositis
- Cirrhosis of the liver, hepatitis
- Waldenström's disease
- Acquired hemolytic anemia, thrombocytopenia
- Mixed connective tissue diseases
- Activation of antigraft implantation immunity
- Primary immunodeficiency states
Decrease in the indicator
- Acquired secondary immunodeficiency states:
- bacterial, viral, protozoal infections with protracted and chronic course of tuberculosis, leprosy, HIV infection, malignant neoplasms
- Heavy burns, injuries, stress
- Aging
- Treatment with cytostatics and immunosuppressants
- Ionizing radiation (in acute period)
- Enhancement of suppressor activity of cellular immunity