Medical expert of the article

Rheumatologist, immunologist

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Causes of high and low NK-lymphocytes (CD16) in blood

Alexey Kryvenko, medical expert
Last reviewed: 06.07.2025

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Diseases and conditions that lead to changes in the number of CD16 lymphocytes in the blood

Increase in the indicator

Activation of anti-transplant immunity, crisis of rejection of donor organs in recipients
Bronchial asthma

Decrease in the indicator

Oncological diseases
Secondary immunodeficiency states, HIV infection
Severe viral infections
Severe burns, injuries, stress
Treatment with cytostatics and immunosuppressants
Ionizing radiation
Taking glucocorticosteroids