Medical expert of the article
New publications
Alcohol and tobacco amblyopia
Last reviewed: 07.07.2025

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Alcohol-tobacco amblyopia usually develops in alcoholics and tobacco smokers who have a deficiency of protein and B vitamins. Most patients violate the diet, getting calories mainly from alcohol.
Alcohol-tobacco amblyopia is manifested by gradual, progressive, bilateral, usually symmetrical deterioration of vision and dyschromatopsia.
[ 1 ], [ 2 ], [ 3 ], [ 4 ], [ 5 ], [ 6 ], [ 7 ], [ 8 ], [ 9 ], [ 10 ]
Symptoms of alcohol-tobacco amblyopia
The optic disc is normal at the onset of the disease in most cases. Some patients have mild temporal pallor, streaky hemorrhages on or around the disc, and slight disc edema.
Visual field defects: bilateral symmetrical centrocecal scotomas. The edges of the defects are difficult to determine with a white object, easier with a red one, since its area is larger.
What's bothering you?
What do need to examine?
How to examine?
Who to contact?
Treatment of alcohol-tobacco amblyopia
Weekly injections of 1000 units of hydroxycobalamin for 10 weeks and multivitamins. Patients should eat a balanced diet and abstain from alcohol and smoking.
The prognosis is good at the onset of the disease and if the patient is treated, but vision may recover slowly. In advanced and refractory cases, persistent vision loss is associated with the development of optic nerve atrophy.