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Thalassemia HbS-B: Causes, Symptoms, Diagnosis, Treatment
Last reviewed: 18.10.2021
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Thalassemia HbS-B is hemoglobinopathy, in which the symptoms are similar to sickle-cell anemia, but less pronounced.
Because of the high incidence of thalassemia HbS and beta-thalassemia in certain population groups, the congenital presence of both anomalies is quite frequent. Clinically, the disease manifests itself as symptoms of mild anemia and signs of sickle-cell anemia, which are usually more rare and less intense. In blood smears, in most cases, mild to moderate severity of microcytic anemia with some sickle-shaped erythrocytes occurs. To establish the diagnosis, you need a quantitative determination of hemoglobin, the level of HbA 2 > 3%. Electrophoresis determines the increase in HbS and the decrease or absence of HbA, there may be an increase in HbF. Treatment, if necessary, is similar to that of sickle cell anemia.