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Morgagni-Stewart-Morel syndrome: causes, symptoms, diagnosis, treatment
Last reviewed: 23.04.2024
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Morganyi-Steward-Morel syndrome is characterized by thickening of the inner plate of the frontal part (frontal hyperostosis), general obesity with a pronounced second chin and fatty apron, usually without stretch marks on the skin, often intracranial hypertension, menstrual cycle disorder, hirsutism, severe headaches mainly frontal and occipital localization, weakening of memory, depression, diabetes mellitus. Perhaps, although rare enough, the emergence of symptoms of diabetes insipidus. The syndrome is more typical for women and most often debuts. During the climacteric period. Nevertheless, it can also occur at a younger age (up to 30 years). The most common incomplete forms of the syndrome. In men it is extremely rare.
Causes of Morgagni-Steward-Morel Syndrome
Refers to hereditary diseases. It is inherited by autosomal dominant type.
The pathogenesis of Morganyi-Steward-Morel syndrome
Dysfunction of the hypothalamic-pituitary region with excessive production of STH and ACTH as a result of hyperfunction of eosinophilic and basophilic cells of the adenohypophysis. Hyperfunction is induced by the releasing factors of the hypothalamus.
Treatment of Morgagni-Steward-Morel Syndrome
Should be aimed at stopping the main manifestations of the disease - obesity, hypertension, depression.
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